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狼疮鼠
    RECENT EFFECT OF REALGAR ON THE RENAL FUNCTION OF LUPUS MICE
    雄黄对狼疮鼠肾功能的近期影响
    Relationship between abnormality of colony-forming units of granulocytes and macrophages and pathogenesis in BXSB lupus mice
    BXSB狼疮鼠骨髓粒-巨噬细胞集落形成单位异常与发病的关系
    Activation of JAK/STAT1 signal transduction pathway in different organs of MRL/lpr lupus mice
    JAK/STAT1信号转导途径在MRL/lpr狼疮鼠不同器官中的活化研究
    The Therapeutically Effects of Sodium Arsenite on Lupus Nephritis of BXSB Spontaneous Lupus Mice
    亚砷酸对BXSB狼疮鼠狼疮性肾炎的治疗作用
    Conclusions Allo-HSCT is an effective treatment method for lupus mice. It may be helpful in improving proteinuria and anti-dsDNA antibody and renal pathological changes of lupus mice. But the incidences of complication and mortality related to transplantation in Allo-HSCT group are higher than those in control group,so the value of Allo-HSCT in the treatment lupu mice has to be further studied.
    结论Allo-HSCT是一种有效的较彻底的治疗重型SLE的方法,其在降低BXSB狼疮鼠尿蛋白,使抗双链DNA抗体转阴及改善肾病理改变方面明显优于传统的治疗方法,但与移植相关的并发症、死亡率较高,有一定的
    Objective:To study the recent effect of realgar on the renal function of lupus mice.
    目的 :研究雄黄对狼疮鼠肾功能的影响。
    Result:Three methods had therapeutic action on lupus mice with renal impariment. There was no significant difference among them(P>0 05).
    结果 :3种治疗方法对狼疮鼠肾损害均有治疗作用 ,3组间疗效差异无统计学意义 (P >0 .0 5 ) ;
    Conclusion:Realgar has some therapeutic action on the renal impairments of lupus mice and hemutopoiesis inhibition and no liver toxicity is found in the early stage.
    结论 :雄黄对狼疮鼠肾损害有一定的治疗作用 ,早期未见造血抑制和肝毒性
    Objective:To investigate the therapeutically effects of sodium arsenite on lupus nephritis of BXSB spontaneous lupus mice.
    目的 :观察亚砷酸对BXSB自发狼疮鼠狼疮性肾炎的治疗作用。
    Objective To study the proliferation of colony-forming units of granulocytes and macrophages (CFU-GM) and relationship with pathogenesis in BXSB lupus mice.
    目的 :研究 BXSB自发性狼疮鼠骨髓粒 -巨噬细胞系的增殖情况与狼疮发病的关系。
    Methods The TCR Vβ6 gene in kidneys and brains from different individuals of aged diseased lupus mice were amplified by reverse transcriptase polymerase chain reaction (RT-PCR) respectively.
    方法用反转录聚合酶链反应(RT-PCR)分别扩增不同成年发病狼疮鼠个体的肾脏、大脑中的TCRVβ6基因,对扩增产物进行基因克隆和DNA测序分析;
 

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