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    STUDIES ON TOXICOKINETICS OF ~3H-SULFOLANE IN RAT AFTER ORAL ADMINISTRATION
    ~3H-环丁砜经口染毒后在大鼠体内的毒代动力学
    EFFECTS OF ORAL ADMINISTRATION OF VANADATEON KIDNEY IN DIABETIC RATS:A MORPHOMETRIC STUDY
    经口给予钒酸盐对糖尿病大鼠肾脏影响的形态计量研究
    A CLINCAL ANALYSIS OF 72 SENILE PATIENT WITH ACUTE ORAL ORGANIC PHOSPHORUS PESTCIDES INTOXICATION
    老年及老年前期经口有机磷农药中毒72例分析
    Experimental Pathological Observation on Subacute Oral Toxicity Induced by Nickel Sulfate
    硫酸镍经口亚急性毒性实验病理观察
    Drug delivery systems (DDS)Ⅲ Oral drug delivery systems
    药物传递系统(DDS)Ⅲ经口给药途经的DDS
    The results show that LD50 of compound sodium nitrophenolate feed on the male rats was 1 210 mg·kg-1,to female rats was 1 000 mg·kg-1 in acute oral toxicities test;
    结果表明:复硝酚钠对雄性大鼠经口LD50为1 210 mg. kg-1,对雌性大鼠经口LD50为1 000 mg.
    The acute toxicity, subchronic toxicity and mutagenicity of aphicidin were investigated. The results of the acute oral test indicated that the LD50 were 38.3 mg/kg to male and female rats, 38.3 mg/kg to male mice and 17.8 mg/kg to female mice, the results of the acute dermal test indicated that the LD50 were 1 470 mg/kg to male rats and 1 210 mg/kg to female rats.
    研究制蚜菌素的急性、亚慢性毒性及致突变性结果表明,急性经口LD50雌雄性大鼠均为38.3mg/kg,雄性小鼠为38.3mg/kg,雌性小鼠为17.8mg/kg,急性经皮LD50雄性大鼠为1470mg/kg,雌性大鼠为1210mg/kg;
    The results showed that LD_50 of the secondary metabolites of Rhizoctonia leguminicola by oral exposure was 226.46 mg/kg. The scope of truth was 158.49-323.59 mg/kg. It was 14-84 times for the cure dosage.
    结果表明,以该代谢产物中苦马豆素的量计算,小鼠经口急性毒性试验的LD50为226.46mg/kg,LD50的95%可信限为158.49~323.59mg/kg,是治疗肿瘤剂量的14~84倍,属于实际低毒级药物。
    Durations of restoring oral in-take and hospitalization in sequential group were obviously shorter than those in TPN-group (P <0.05).
    序贯化组恢复经口进食时间及住院时间显著短于TPN组(P<0.05)。
    [Methods] Three dose groups(100,333 and 1 000 mg/kg respectively) and a control group were formed to conduct 30 days' oral toxicity; the weight,routine blood,the weight of the immune organs and pathological changes were observed.
    方法以100、333、1 000 mg/kg 3个剂量组和1个阴性对照组对大鼠30 d经口染毒,观察体重、血常规、免疫器官重量和病理组织学改变。
    [Results] Both the acute oral toxicity LD(50)and the acute dermal toxicity LD(50)(4h) were more than 5000 mg/kg in rats; there was no irritation to the skin and eye of the rabbits;
    结果该受试物对雌、雄大鼠急性经口LD50>5000 mg/kg,对雌、雄大鼠急性经皮LD50(4 h)>5000 mg/kg,对家兔急性皮肤刺激反应均值积分为0,对家兔眼平均刺激指数为0;
    Results showed that the mice were ingested the tea sample by means of maximal tolerant dosage(40 ml/kg·BW)method, The median acute oral lethal dose(LD50)>40 ml/kg·BW and it equals to LD50>20 g/kg·BW of the dried tea sample. It can be classified as the class of nontoxic .
    研究结果表明:受试物茶样采用最大耐受剂量法(40ml/kg·BW)经口染毒受试小鼠,测得小鼠经口急性毒性试验LD50>40ml/kg·BW,换算为茶叶量为LD50>20g/kg·BW,可以判定为无毒;
    The toxicity test indicated that the acute oral LD50 for mice was 492.72 mg/kg,the 48 h-EC50 for Daphnia magna straus(Cladocera crustacea)was 143.61 mg/L,the 96h-LC50 for Brachydanio rerio was 84.17mg/L.
    THPS对斑马鱼的96h-LC50为84.17mg/L; THPS对健康昆明种小鼠的经口LD50为492.72mg/kg。
    LD50 was 21.5 mg/kg in female rats and male rats by oral, LD50 was 68.1 mg/kg in female mice and 38.3 mg/kg in male mice by oral, LD50 was >2 000 mg/kg in female rats and male rats by dermal.
    结果显示,大鼠经口LD50雌雄性均为21.5mg/kg,小鼠经口LD50雌性为68.1mg/kg,雄性为38.3mg/kg,大鼠经皮LD50雌雄性均大于2000mg/kg。
    Methods The Wistar rats were treated with oral exposure dose 0.1,2 and 40 mg/kg of lanthanum chloride(LaCl3) respectively,after 90 days the rats were sacrificed and the blood was collected for blood general index examination.
    方法分别用0.1、2和40 mg/kg体重剂量的三氯化镧(LaCl3)给大鼠经口灌胃,每天一次,90 d后处死;
    [Results]The toxicity of mouse acute oral toxicity test with peracetic acid(LD50=926 mg/kg) was low.
    [结果]过氧乙酸对小鼠急性经口LD50=926 mg/kg,属低毒;
    It had no irritation to the skin by mouse acute oral toxicity test with 2 000 mg/L of peracetic acid (LD50>5 000 mg/kg).
    其含2 000 mg/L过氧乙酸溶液对小鼠急性经口LD50>5 000 mg/kg及对皮肤刺激属无刺激性;
    After the tumor excision, the oral defect was reconstructed with myocutaneous platysma flap which had submandibular pedicle and contained external jugular vein.
    方法先形成蒂在颌缘下包含颈外静脉的颈阔肌肌皮瓣,待口腔肿瘤切除后,将肌皮瓣经口底隧道引入口腔修复缺损。
    Results:The oral LD(50) of hepatic peptide in both mice and rats was more than 20.0 g/kg·BW,so the hepatic peptide belonged to actual non-toxicity.
    结果:复肝肽对雌雄性小鼠和雌雄性大鼠经口LD50均大于20.0 g/kg体重,属无毒类。
    Determine the body total activity of Superoxide Dismutase(SOD), CuZn-SOD, Maleic Dialdehyde(MDA) via breeding drosophila with DEHP through oral cavity.
    通过对果蝇经口喂饲DEHP后测定体内总SOD、CuZn-SOD活力及MDA含量;
 

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