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rb基因
    Deletion of Rb Gene in Human Stomach Cancer
    Rb基因在人胃癌中异常的初步观察
    DETECTION OF LOSS OF HETEROZYGOSITY OF RB GENE BY VNTR POLYMORPHISM ANALYSIS IN HUMAN LEUKEMIA
    以VNTR多态性分析检测人类白血病RB基因的杂合子性缺失
    STUDY ON THE EXPRESSION OF RB GENE DURING GAMETOGENESIS OF KUNMING MICE
    RB基因在小鼠生殖细胞发生过程中的表达研究
    Preliminary analysis of p53 gene and Rb gene mutation in ovarian cancer tissue.
    p~(53)基因与Rb基因在卵巢癌组织中突变的初步分析
    Significance of p16 and Rb gene protein expression in primary lung cancers
    p16和Rb基因蛋白在肺癌中的表达
    Polymorphism of Rb gene VNTR in the aged people
    老年人群Rb基因VNTR的多态性分布
    Rb gene XbaI polymorphism in relation to atherosclerosis in Shaanxi elder population
    陕西地区老年动脉粥样硬化群体Rb基因XbaI酶切位点多态性研究
    Effect of Exogenous Rb Gene on Expression of CD36 Gene in U937 Cells Treated with Oxidized Low Density Lipoprotein
    外源性Rb基因对U937细胞泡沫化过程中CD36表达的影响
    Advances in the Study of Rb Gene and Cell Senescence
    Rb基因与细胞衰老的研究进展
    Purpose To study the expression of p16 and Rb gene proteins in primary lung cancers.
    目的:研究p16和Rb基因蛋白的表达与肺癌临床病理学特征的关系。
    AIM To investigate distribution of polymorphism of Rb gene intron 20 VNTR in the aged and whether there is change between youth and the aged in polymorphism of Rb gene intron20 VNTR, To study whether polymorphism of Rb gene VNTR is associated with cellular aging.
    目的 探讨老年人群 Rb基因 2 0内含子的 VNTR多态性分布 ,并与青年群体比较是否发生改变 ,以此研究老年人的衰老机制 .
    Results (1) Two fragments of alleles (945 bp, 630 bp+315 bp) of Rb gene (intron17) were found in old population, with genotype frequency being A/A 0 20, A/B 0 45, B/B 0 35, showing no significant difference between the aged and the youth.
    结果 在老年组中 ,Rb基因 17内含子位点共检测出 2个等位基因片段 :945bp(A)及 6 30 +315bp(B) ,基因型频率 :A/A0 2 0 ,A/B 0 45 ,B/B 0 35 ,等位基因频率 :A 0 43,B 0 5 7;
    SPECTRUM AND CHARACTERIZATION OF RB GENE POINT MUTATONS IN PRIMARY TUMORS AND SAMATIC CELLS OF PATIENTS WITH RETIOBLAS-TOMA
    RB患者肿瘤及体细胞中Rb基因点突变谱及其特征和意义
    Rb gene is a cancer suppressor gene. Its product, Rb protein has close relation with the regulation of cell transformation, cell cycle and transcription.
    Rb基因是一种抗癌基因,其产物Rb蛋白与细胞转化、细胞周期调节及转录调控有密切关系。
    By Southern Blot hybridization, we have tested cancer tissues of nine stomach cancer patients and one cell line BGC-823 with Rb gene probe, finding that the Rb gene of all the tissues and the cell line are abnormal as compared with that of normal human blood tissues.
    我们用Southern印迹杂交法,以Rb基因为探针,检测了九例胃癌患者的癌组织和一个胃癌细胞株,发现它们与正常人血相比Rb基因全部呈现异常。
    Among the cancer tissues of the nine patients, five have partial deletion of Rb gene, three as well as the cell line have complete deletion of Rb gene.
    其中5例发生Rb基因部分缺失,3例及人胃腺癌细胞株BGC-823全部缺失。
    This provides evidence that the loss of heterozygosity of the RB gene is probably related to the leukemogenesis of ALL.
    RB基因功能失活在急淋的发病中可能也起一定的作用。
    PURPOSE:To investigate the frequency and character of Rb gene point mutations inprimary tumors and somatic cells of patients with retinoblastoma.
    目的:研究RB患者肿瘤及体细胞中Rb基因点突变的频率、特征及其在肿瘤遗传易感性的传递及肿瘤形成机制中所起的作用。
    Objective\ To study the effect of foreign retinoblastoma(Rb)gene mediated by recombina adenovirus vector on vascular smooth muscle cell(SMC)and the possibility by using Rb gene for gene therapy of atherosclerosis and artery restenosis.
    目的探讨腺病毒载体介导的Rb基因对血管平滑肌细胞的作用,及其应用于动脉粥样硬化及动脉再狭窄基因治疗的可能性。
    Methods\ Rb gene recombinant adenovirusvector was con structed to transfect into rabbits' aortic SMC in vitro.
    方法构建Rb基因的重组腺病毒载体,体外转染兔血管平滑肌细胞。
 

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