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维甲酸受体
    EXPRESSION OF RETINOIC ACID RECEPTOR αIN HUMAN BREAST CANCER CELL LINES
    维甲酸受体α在乳腺癌细胞中的表达
    Comparative study of two fusion retinoic acid receptor α in acute promyelocytic leukemia
    两种早幼粒细胞白血病融合维甲酸受体α的比较研究
    Binding activity of retinoids with recombinant human retinoic acid receptor RAR α
    几种新维甲类化合物与人重组维甲酸受体 RAR α 结合活性研究
    A new variant translocation of subtype S of promyelocytic leukemia/retinoic acid receptor alpha fusion gene
    一种新的早幼粒细胞白血病/维甲酸受体α融合基因S亚型变异易位
    Study on Relationship Between Retinoic Acid Receptor and Vitamin D Receptor in Skin
    皮肤中维甲酸受体和维生素D受体关系研究进展
    Mutation in Intron of Retinoic Acid Receptor Alpha in Patients with Psoriasis Vulgaris
    寻常性银屑病患者维甲酸受体α内含子碱基突变
    Mutation in exon 6 of retinoic acid receptor alpha in patients with psoriasis vulgaris
    寻常型银屑病患者维甲酸受体α基因第6外显子碱基突变
    Establishment of high-throughput drug screening model targeting retinoic acid receptor in cells
    维甲酸受体为靶点的高通量药物筛选细胞模型的建立
    atRA exerts its effects by binding the retinoic acid receptor (RAR) and retinoid X receptor (RXR).
    己证实atRA通过核内维甲酸受体(RAR)和维甲类X受体(RXR)的激活而起作用。
    Initially, atRA activates a heterodimer RAR/RXR, which further recognizes and binds to retinoic acid receptor response element (RARE) consensus sequence, thereby activating or repressing target gene transcription.
    AtRA可激活异二聚体RAR/RXR,后者通过识别和结合维甲酸受体反应元件(RARE),进而引起靶基因的转录激活或转录抑制。
    WT1 can regulate the expression of the CSF-1, IGF-IR, bcl-2, c-myc and retinoic acid receptor genes. So it regulates the hematopoiesis in this way.
    WT1能调控CSF-1基因、TGF(转化生长因子)基因、bcl-2、c-myc以及维甲酸受体基因的表达,从而调节造血细胞的功能。
    To study the regulation of bFGF,ATRA,VD3,DEX and BMP-2 on the differentiation of neural stem cells and the relation between the expression of retinoic acid receptor mRNA and the processes of differentiation.
    研究bFGF、BMP-2、ATRA、VD3、DEX对神经干细胞分化的诱导作用及该作用与维甲酸受体mRNA表达的关系。
    Molecular studies of chromosomal translocation (15; 17) in acute promyelo-cytic leukemia (APL) have shown that retinoic acid receptor A (RARA) gene on chromosome 17 is juxtaposed to the PML gene on chromosome 15. This results in a PML-RARA chimeric gene.
    对急性早幼粒细胞白血病(APL)中t(15;17)染色体易位的分子生物学研究显示,17号染色体上的维甲酸受体α(RARA)基因与15号染色体上的PML基因并置,并产生PML-RARA融合基因。
    In studying the mechanisms responsible for the response of APL cells to ATRA, we and others have been able to characterize the molecular biology of t (15; 17 ) which fuses the retinoic acid receptor aaaaaaaaaaaaaaa(RARA) gene with a chromosome 15q locus, PML.
    在研究APL细胞对ATRA的应答机理中,我们和其他作者阐明了t(15;17)的分子生物学,发现它使维甲酸受体α基因(RARA)与15号染色体上的一个位点PML发生融合。
    Nuclear retinoic acid receptor β (RAR β) was the key gene that mediated retinoids activity for squamous carcinoma cells.
    维甲酸受体β(Retinoicacidreceptorsβ,RARβ)是介导维甲酸对鳞癌细胞起作用的关键基因。
    Conclusion: The mitochondrion gene expression by ATRA might be regulated through the interaction of retinoic acid receptor (RAR) with RARE in mitochondrion genome
    结论:维甲酸受体与线粒体基因组维甲酸反应元件相互作用可能是其调控线粒体基因的表达。 维甲酸除调控核基因外,亦可对线粒体基因进行直接调控。
    s: AIM To study the pharmacological effects of tetra arsenic tetra sulfide on apoptosis of NB4 cells and the change of promyelocytic leukemia retinoic acid receptor α(PML RARα) fusion gene and its expression product during this process.
    目的 研究四硫化四砷对NB4细胞的促凋亡作用及这一过程中早幼粒细胞白血病 维甲酸受体α(PML RARα)融合基因及其表达产物的变化。
    Objective To investigate the effect of retinoic acid (RA) on retinoic acid receptor (RAR) and proliferating cell nuclear antigen (PCNA) in colorectal carcinoma.
    目的探讨维甲酸(RA)对结直肠癌组织维甲酸受体(RAR)和增殖细胞核抗原(PCNA)表达的影响。
    Objective:To investigate the regulatory effect of nuclear receptors including peroxisome proliferator activated receptorγ (PPARγ) and α(PPARα),retinoic acid receptor(RAR),retinoid X receptor (RXR),vitamin D receptor (VDR),thyroxin receptor (TR) and glucocorticoid receptor (GR) agonist on aromatase activity in human ovarian granulosa and breast cancer MCF 7 cells.
    目的 :探讨各种核受体包括过氧化酶体增生物激活受体 γ(PPARγ)和 α(PPARα)、维甲酸受体 (RAR)、维甲类 X受体 (RXR)、维生素 D受体 (VDR)、甲状腺素受体 (TR)和糖皮质激素受体 (GR)的激动剂对人卵巢颗粒细胞和乳腺癌 MCF- 7细胞芳香化酶活性的调节作用。
    Objective To study the expression of retinoic acid receptor β(RAR β)mRNA and p16, p53, Ki67 proteins in squamous cell carcinoma of the esophagus and its precursor lesions in a high risk population.
    目的 研究食管癌高发区人群的正常食管上皮、癌前病变及癌组织活检标本中 ,维甲酸受体 β(RAR β)mRNA、p16、p5 3和Ki6 7蛋白的异常表达及其与食管癌发生的关系。
 

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