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视黄酸受体
    The Expression of Retinoic Acid Receptor Genes in Lymph Nodes of Young Children and B Cell Development
    视黄酸受体基因在小儿淋巴结的表达与B细胞发育的研究
    ROLE OF RETINOIC ACID RECEPTOR IN ANTIBODY SYNTHESIS OF CORD BLOOD LYMPHOCYTES
    视黄酸受体在脐血淋巴细胞抗体生成中的作用
    Expression of Retinoic Acid Receptor Genes in Children's Thymus
    视黄酸受体基因在儿童胸腺中的表达
    Progress on Retinoic Acid Receptor Gamma Gene
    视黄酸受体γ基因的研究进展
    THE EXPRESSION OF RETINOIC ACID RECEPTOR GENES IN LYMPH NODES OF YOUNG CHILDREN AND THE DEVELOPMENT OF B CELLS
    视黄酸受体基因在小儿淋巴结的表达与B细胞的发育
    Cells separated from lymph nodes were divided into 5 groups: Retinoic acid (RA), Retinoic acid plus Ro 41-5253, retinoic acid receptor antagonist (RA+Ro), lipopolysaccharide (LPS), lipopolysaccha-ride plus Retinoic acid (LPS+RA) and control cultured in vitro.
    淋巴结分离细胞进行体外培养,分为RA组,RA+视黄酸受体α(RARα)拮抗剂(Ro41-5253)组(RA+Ro),脂多糖组(LPS),(LPS+RA)组和对照组。
    Retinoic acid receptor α (RARα) expression level was low in three gastric carcinoma cell lines, it was increased obviously in MGc80 3 and BGC 823 cells, but not in MKN45 cell after induction of ATRA.
    视黄酸受体RARα基因在3株细胞中呈低水平表达,经ATRA诱导后,在MGc803和BGC823细胞中表达水平提高,但在MKN45细胞中表达水平不变。
    Distinct ways between RARα (retinoic acid receptor α) and RARβ on inhibition of AP 1(activator protein 1) activity in gastric cancer cells and their relationship with ATRA (all trans retinoic acid) action were investigated.
    研究胃癌细胞中视黄酸受体RARα和RARβ抑制活化蛋白 1(activatorprotein 1,AP 1)活性的不同方式及其与全反式视黄酸 (ATRA)作用的相关性 .
    Methods Stellate cells were isolated from healthy rat livers and cultured. After stimulated with 1 ng/ml transforming growth factor beta 1, subcultured hepatic stellate cells were treated with or without 1 nmol/ml retinoic acid. MTT assay, immunocytochemistry for p16, p21, p27 and α-smooth muscle actin protein, in situ hybridization for retinoic acid receptor beta 2 and p16, p21 and p27 mRNA and quantitative image analysis (partially) were performed.
    方法 分离、培养正常大鼠肝星状细胞,传代细胞经1ng/ml转化生长因子β1刺激后再以1nmol/ml视黄酸处理,然后采用MTT法、免疫细胞化学法、原位杂交技术并结合图像定量分析观察细胞增殖、α-平滑肌肌动蛋白、视黄酸受体β2及p16、p21与p27等基因的表达情况。
    Results Retinoic acid markedly inhibited hepatic stellate cells proliferation (41.50%, P<0.05), decreased the protein level of α-smooth muscle actin (55.09%, P<0.05), and induced hepatic stellate cells to express retinoic acid receptor beta 2 mRNA.
    结果 视黄酸明显抑制星状细胞增殖(41.50%, P<0.05)、降低α-平滑肌肌动蛋白水平(55.09%, P<0.05),并诱导视黄酸受体β2基因的表达。
    The real time quantitative RT-PCR assay was used to detect the retinoic acid receptor α (RARα) mRNA expression on thymocyte.
    胸腺细胞抽提的 RNA采用实时定量 PCR法检测视黄酸受体 α( RARα) m RNA的表达。
    The real time quantitative RT-PCR assay was used to detect the retinoic acid receptor (RAR) mRNA expression in thymocytes.
    胸腺细胞抽提的RNA采用实时定量PCR法检测视黄酸受体α(RARα) mRNA的表达。
    This review introduced retinoic acid receptor families, the structure of retinoic acid receptor gamma gene and its isomorphic gene , expression and regulation of retinoic acid receptor gamma gene.
    对视黄酸受体家族、视黄酸受体γ基因和视黄酸受体γ同工型基因的结构以及视黄酸受体γ的表达与调控等方面进行了综述.
    The change of cell proliferative cycles and the expression of retinoic acid receptor beta (RARβ) were detected before and after ATRA treatment.
    ATRA作用前后检测细胞增殖周期和视黄酸受体β(RARβ)的变化。
    Objective Retinoic acid receptor(RARα) selective antagonist,Ro41-5253(Ro) was used in the counteract test,to confirm the role of RARα in enhancement of IgM synthesis in cord blood lymphocytes(CBLs) by retinoic acid(RA).
    目的通过采用视黄酸受体(RARα)选择性拮抗剂Ro41-5253(Ro)进行阻抑实验,以进一步明确视黄酸(RA)对脐血淋巴细胞IgM生成的促进作用是否通过RARα途径调节。
    The Relationship between Alteration of Retinoic Acid Receptor Transcriptional Activity and the Growth of Cancer Cells
    视黄酸受体转录水平的改变与癌细胞生长的关系
    Regulation of retinoic acid receptor on cytokine expressions in cord blood lymphocytes
    视黄酸受体在脐血淋巴细胞细胞因子表达中的调节作用
    Advances of the Relationship between Nonsyndromic Cleft Lip with or without Cleft Palate and the Retinoic Acid Receptor Alpha Gene
    非综合征性唇腭裂与视黄酸受体-α基因关系的研究
    Role of Retinoic Acid Receptor Antagonist on Immunoglobulin M Synthesis by Cord Blood Lymphocytes
    视黄酸受体拮抗剂对脐血淋巴细胞免疫球蛋白M生成的作用
    The real time quantitative RT-PCR assay was used to detect the retinoic acid receptor mRNA expression in thymus.
    结论:胸腺细胞与胸腺基质细胞均表达视黄酸受体α基因,视黄酸受体α途径的活化在促进CD4+细胞的发育中起重要作用。
 

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