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移植瘤的
    INHIBITORY EFFECTS OF ACTINOMYCIN 23-21 ON TRANSPLANTED TUMORS OF HUMAN NASOPHARYNGEAL CARCINOMATOUS CELLS AND GASTRIC CARCINOMATOUS CELLS IN NUDE MICE
    放线菌素23-21对裸小鼠人鼻咽癌细胞系移植瘤和人胃癌细胞系移植瘤的抑制作用
    THE PHOTODYNAMIC KILLING EFFECT OF PHOTOSENSITIZING AGENT DE-03 ON CANCER CELLS AND TRANSPLANTED TUMORS AND ITS PHOTOTOXIC REACTION
    光敏剂DE-03对癌细胞和移植瘤的光动力杀伤作用及光毒反应
    Objective: To study the curative effect of the pcDNA3/AFP/angio/tk targeted fusion gene system on subcutaneously transplanted tumors of human primary hepatic carcinoma.
    目的:研究pcDNA3/AFP/angio/tk靶向性融合基因系统对人原发性肝癌皮下移植瘤的治疗效果。
    The difference in the tumor killing effects of non Ag-CTL on A549 and HepG2 cells was not significant. In vivo experiments showed that Ag-CTL significantly inhibited the growth of transplanted tumors in nude mice compared with NS and non Ag-CTL (P<0.05). The difference between NS group and non Ag-CTL group was significant(P<0.05).
    体内实验表明,Ag-CTL可有效抑制裸鼠皮下移植瘤的生长,与生理盐水组(NS组)、non-Ag-CTL组相比在统计学意义上有显著差异(P<0.05),non-Ag-CTL组与NS组相比在统计学意义上有差异(P<0.05)。
    Results: (1) The local invasion and metastasis of of tumors were present in all the above 4 models for a long time. The local invasion rate and the pulmonary metastasis rate of subcutaneously transplanted tumors were 59.70% (40/67) and 37.10% (23/62), respectively.
    结果:(1)上述4种肿瘤模型的局部侵袭和转移均长期存在:皮下移植瘤的局部侵袭率为59.70%(40/67),肺内转移率为37.10%(23/62);
    The pulmonary metastasis rate of abdominally transplanted tumors was 59.02%(36/61).
    腹腔移植瘤的肺内转移率为59.02%(36/61);
    The intra-hepatic and pulmonary metastasis rate of the othotopically transplanted tumors were 18.18%(4/22) and 31.82% (7/22), respectively.
    肝原位移植瘤的肝内转移率为18.18%(4/22),肺内转移率为31.82%(7/22);
    (4)The DNA contents had a wide distribution (from 2c to 6c) in abdominally transplanted tumors and the pulmonary metastatic tumors;
    (4)腹腔移植瘤的瘤细胞群体与肺转移瘤的瘤细胞群体DNA含量分布范围明显增宽,2C~6C不等,峰值明显右移,前者的分布范围比后者更宽;
    Inhibitory effect of antineoplastic polypeptide from Buthus martensii venom on transplanted tumors and H_(22) cells:An experimental study
    蝎毒抗肿瘤多肽对小鼠肝癌细胞H_(22)及移植瘤的抑制作用
    An Experimental Study on the Inhibitory Effects of Qi-Boosting Toxin-Resolving Granule on HNE3 Cells and Transplanted Tumors with This Cell Line in Nude Mice
    益气解毒颗粒对HNE3细胞及其裸鼠移植瘤的抑制作用
    Antitumol effect of an organogermanium compound on transplanted tumors(S_(180),C_(57),EAC Solid tumor)in mice was described. When the com- pound was given to the mice with tumors at 100 to 200mg/kg daily,po or ip 10 days,the inhibition rate of the tumor weights was 77-91%.
    本文报道一种有机锗化合物对小鼠移植瘤的影响,以此药(200mg/ks、po、ip)给荷瘤动物连续灌胃10天时,S_(180)、EAC(实体瘤)和肺癌 C_(57)被抑制,其抑癌率为73~91%。
    At ACT 23-21 50μg/kg, the inhibition rate for transplanted tumors of CNE-2Z and MGc-803 were 58.4% (P<0.05)and 68.7%(P<0.05 ) , respectively.
    放线菌素23—21 50μg/kg,对CNE-27移植瘤和MGc803移植瘤的抑制率分别为58.4%(P<0.05)和68.7%(P<0.05)。
    At Act 23--21 50μg/kg, the inhibition rate for transplanted tumors of CNE-2Z and MGc-803 were 58% (P<0. 05) and 68. 7% (P<0. 05), respectively.
    50μ/kg对CNE-2Z移植瘤和MGHC-803移植瘤的抑瘤率分别为58%和68.7%。
    Lewis cell line and its mouse transplanted tumors radiated by 0 60 Co were observed under electron microscopy,DNA gel electrophoresis and flow cytometry.
    对60Co照射的Lewis细胞及其小鼠移植瘤进行电镜、DNA电泳和流式细胞术观察,研究照射Lewis细胞凋亡的时间、剂量效应关系,以及对小鼠移植瘤的影响。
    Methods Cell culture and nude mice experiment in vivo were used, F 1, S 1 and nude mice transplanted tumors were analyzed for DNA ploidy and cell cycle distribution by feulgen staining and image analysis.
    方法 采用细胞培养及裸鼠体内实验,用Feulgen染色法和图像分析方法观察F1、S1细胞及其裸鼠移植瘤的DNA倍体及细胞周期的分布情况。
    Results sFlk-1 exhibited no inhibiting effects on the growth of RB cells in vitro, while sFlk-1 combined with ExTek restrained the growth of the transplanted tumors obviously in vivo, and the anti-growth rate is 80.04%.
    结果sFlk1对体外培养的RB细胞的生长无明显抑制作用。 但在体内sFlk1和ExTek联合应用能够显著抑制RB移植瘤的生长,抑瘤率为80.04%。
    Histopathology examination of transplanted tumors showed primary lymphoma of the liver(non-Hodgkin's,B cell).
    移植瘤的病理组织学为肝非霍奇金B细胞性恶性淋巴瘤。
    And mice of 5 groups were injected with esophageal carcinoma EC9706 cells transfected with 20 μmol/L ASODNs for 72 h (ASODN-1,ASODN-2,ASODN-3,ASODN-4, and ASODN-3 ) and N-ODN as experimental groups, with liposomes without ASODN as control group, and PBS as negative control group, respectively. The growth of nude mice transplanted tumors were observed for five weeks.
    将20μmol/L不同基因位点的hTRASODN(ASODN1、ASODN2、ASODN3、ASODN4及ASODN5)和无关序列寡核苷酸(N ODN)分别转染食管癌EC9706细胞,72h后采用裸鼠背部皮下注射的方法进行裸鼠体内成瘤实验,连续5周观察裸鼠体内食管癌移植瘤的生长情况。
    Effects of human telomerase RNA antisense oligodeoxynucleotide on esophageal transplanted tumors in nude mice
    人端粒酶RNA反义寡核苷酸靶向治疗对裸鼠食管癌移植瘤的作用
    Eesults showed tha morphological and functional characteristics of the transplanted tumors to be basically identical to the parent tumor's cell.
    结果显示,移植瘤的形态和功能特性与瘤源基本一致。
 

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