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移植瘤
    INHIBITORY EFFECTS OF ACTINOMYCIN 23-21 ON TRANSPLANTED TUMORS OF HUMAN NASOPHARYNGEAL CARCINOMATOUS CELLS AND GASTRIC CARCINOMATOUS CELLS IN NUDE MICE
    放线菌素23-21对裸小鼠人鼻咽癌细胞系移植瘤和人胃癌细胞系移植瘤的抑制作用
    Results The growth rate of transplanted tumors was 100 percent.
    结果BALB/c裸小鼠后肢皮下注射Tca-8113细胞悬液,移植瘤成功率达100%;
    The Comparison among the Survival Times after Different Ablation Therapy to the Transplanted Tumors on the Mice and the Expression of the p27、bcl-2 and Survivin Proteins of the Tumors
    不同消融方法处理小鼠移植瘤后小鼠生存时间及肿瘤组织p27、bcl-2和survivin表达的比较
    At ACT 23-21 50μg/kg, the inhibition rate for transplanted tumors of CNE-2Z and MGc-803 were 58.4% (P<0.05)and 68.7%(P<0.05 ) , respectively.
    放线菌素23—21 50μg/kg,对CNE-27移植瘤和MGc803移植瘤的抑制率分别为58.4%(P<0.05)和68.7%(P<0.05)。
    At Act 23--21 50μg/kg, the inhibition rate for transplanted tumors of CNE-2Z and MGc-803 were 58% (P<0. 05) and 68. 7% (P<0. 05), respectively.
    50μ/kg对CNE-2Z移植瘤和MGHC-803移植瘤的抑瘤率分别为58%和68.7%。
    The authors measured the dielectric constant of biological tissues during cryosurgery on the transplanted tumors in nude mice.
    作者们在冷冻治疗裸鼠移植瘤过程中测量了生物组织的介电常数。 低温生物介电谱揭示:组织的相变过程是连续的,从0℃~-80℃。
    Results The transplanted tumors disappeared in 1 mouse of CD3AK group, significant difference in the anti metastatic effect was found between the CD3AK group (2/7 mice with metastasis) and the control group (8/10 mice with metastasis).
    结果观察到CD3AK组1只裸鼠移植瘤消退,2/7只出现转移灶,与对照组8/10只裸鼠出现转移灶比较差异有显著性(P<0.05)。
    Lewis cell line and its mouse transplanted tumors radiated by 0 60 Co were observed under electron microscopy,DNA gel electrophoresis and flow cytometry.
    对60Co照射的Lewis细胞及其小鼠移植瘤进行电镜、DNA电泳和流式细胞术观察,研究照射Lewis细胞凋亡的时间、剂量效应关系,以及对小鼠移植瘤的影响。
    Results After using Coptis Chinensis compound for 30 days, the size of transplanted tumors were remarkably reduced, and the inhibition rate of tumor growth was 29.5%.
    结果 :复方黄连处理移植瘤裸鼠 30d后 ,移植瘤明显减小 ,其抑瘤率为 2 9.5 %。
    Results: 65 % (26 / 40) of the transplanted human lung tumor tissues were survival whereas in the control mice the transplanted tumors were totally rejected.
    结果 :移植肺肿瘤在模型动物体内存活 ,成功率可达65 %(26/40) ,而对照组小鼠体内移植瘤全部被排斥 ,不能存活。
    Conclusion ①RhTNF-α can suppress SACC transplanted tumors in nude mice by inducing apoptosis. Cells proliferation were arrested in G 1 phase.
    结论 ①rhTNF -α可抑制裸鼠SACC移植瘤生长 ,使细胞增殖在G1 期发生阻滞。
    The average volume of transplanted tumors and MVD in bFGF group were 180% and 146% above control respectively; those in bFGF-MAb group were 63.7% and 62.8% above control respectively.
    b FGF组移植瘤体积和 MVD分别是对照组的 1.80倍和 1.4 6倍 (P<0 .0 5 ) ,b FGF- MAb组移植瘤体积和 MVD分别是对照组的 6 3.7%和 6 2 .8% (P<0 .0 5 )。
    Methods Nude mouse model of transplanted tumor of colorectal carcinoma was established and treated by intraperitoneal injection of WPG. The activity of protein tyrosine kinases(PTK), protein kinase C(PKC)α, βⅠ, βⅡ, γ, ε, ζ and the density of positive nuclear factor-κB(NF-κB) cell in transplanted tumors were measured.
    方法 以结直肠癌裸鼠移植瘤为动物模型,用膜结合法、激光共聚焦显微镜和免疫组织化学法检测结直肠癌移植瘤和肿瘤对照组各20只BALB/c(nu/nu)裸鼠的蛋白酪氨酸激酶(PTK)和蛋白激酶C(PKC)α、βⅠ、βⅡ、γ、ε、ζ的活性以及核转录因子(NF)-κB的阳性细胞密度。
    Results After treatment with WPG, the activity of PTK、average fluorescent strength of PKCα and density of positive NF-κB cell in transplanted tumors were significanfiy lower than those in untreatment control group(P<0.01).
    结果 结直肠癌棵鼠移植瘤经完整肽聚糖处理后,其PTK活性和PKCα的平均荧光强度以及NF-κB的阳性细胞密度均显著低于肿瘤对照组(P<0.01);
    DNA content,DI value,5C and >5C of F1 and transplanted tumors were higher than those of S1 group with a great statistical significance(P<0.01).
    F1细胞及裸鼠移植瘤DNA含量、DI值、5C及 >5C比例均高于S1组 (P <0 .0 1)。
    DNA content, 5C and >5C of F 1were higher than those of S 1 (P<0.01). 3-4C in F 1 and transplanted tumors were lower than in S 1 groups (P<0.01).
    F1细胞及裸鼠移植瘤DNA含量、5C、>5C比S1组高(P<0.01),F1细胞及裸鼠移植瘤3-4C比例低于相应S1组(P<0.01)。
    G 2/M phase of F 1 and transplanted tumors were both higher than those of S 1 groups, G 0/G 1 phase of F 1 and transplanted tumors were lower than those of S 1 groups (P<0.01-0.05). S phase of F 1 cell was lower than of S 1 cell(P<0.01).
    F1细胞及其裸鼠移植瘤G2M比例均高于相应S1组,G0G1期低于S1组(P<0.05-0.01),F1细胞的S期比例低于S1细胞(P<0.01)。
    RESULTS:After treatment with Coptis chinensis for 30 days,the transplanted tumors were remarkably reduced in size. Meanwhile,expression of 335 genes was altered,of which 242 were down regulated and 93 were up regulated.
    结果:复方黄连处理30d后,移植瘤明显减小,同时有335条基因的表达发生改变,即242条基因表达下调和93条基因表达上调。
    The distribution of H22 cell cycle was demonstrated by flow cytometry (FCM), and the levels of pRB and E2F 1 in cultured H22 cells and transplanted tumors were tested by immunohistochemistry.
    流式细胞术(flowcytometry,FCM)检测细胞周期时相分布; 免疫组织化学方法检测体外培养H22细胞株和移植瘤组织pRB和E2F1的蛋白水平。
    Methods To observe the difference between sublines H5 and S1 of the cell line CNE-2Z in the radiosensitivity of their transplanted tumors in nude mice, the difference between H5 and S1 in their apoptosis-inducing capacity and that in apoptosis-related protein expression were detected by FCM, fluorescence microscope and Western-blot.
    方法 观察人鼻咽癌细胞系CNE 2Z亚克隆株H5和S1的裸鼠移植瘤放射敏感性的不同 ; 用流式细胞仪、荧光显微镜、Western blot检测H5和S1凋亡能力的不同及凋亡相关蛋白表达的差异 ;
 

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