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抗原缺失
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  “抗原缺失”译为未确定词的双语例句
     The down-regulation of HLA-I antigen was distinguished in the tissue in which the HPV16,18, E6 were positive.
     在HPV16、18E6阳性表达组织中其HLAⅠ抗原缺失明显增加。
短句来源
     The declension rate of HLA-A, B, C antigens increased with the decreasing of tumor's differentiation in NSCLC ( P < 0. 05 ) , but there was no significant relation between the rate and TN stage of the patients.
     非小细胞肺癌中随着肿瘤分化程度下降,HLA-A,B,C抗原缺失率将增加(P<0.05),而与病人的TN分期无关;
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     The clinically important Kidd(JK) blood group antigens are carried by the UT-B in red cells, and Human Lacking of JK antigen are also called Jknull .
     UT-B蛋白在红细胞膜上又称为JK血型抗原,JK抗原缺失者通常称为Jknull表型。
短句来源
     Furthermore, the loss frequency of HLA--ABCantigen was much higher in early/small tumors(60%)than in advanced ones(15.79%).
     且HLA-ABC抗原缺失率在早期癌(60.0%)明显高于中晚期癌(15.79%);
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     RESULTS 148 cases (67%) were absent of HBeAg and 72 cases (32%) were HBeAg positive.
     [结果 ]乙型肝炎e抗原缺失者 148例 ,占 6 7% ,乙型肝炎e抗原阳性者 72例 ,占32 % .
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  相似匹配句对
     Lacking of 6 antigenic sites took place at LIU strain after 446 site.
     而Liu株抗原位点在446位后缺失
     The relation between HLA class 1 down-regulation and cervical cancer
     人类组织相容性抗原-Ⅰ缺失与宫颈癌的相关性研究
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     Uresase detection, HE, Fuchsin staianing and immunohistochemical analysis of H. pylori IgG antigen were conducted .
     pylori抗原(HPAg)。
短句来源
     Antigen B derived from sheep E.
     抗原 B与感染 E.
短句来源
     Discussion on the Shortage of the Informatization Strategy
     信息化战略的缺失
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In this article, O antigens of Salmonella typhi H901 L-forms were tested with monovalcnt and AFO polyvalent antisera. No O9 anti-gen specific for S. typhi was found with monovalent antiserum on S. typhi H 901 L-forms, and L-forms could react but weakly with AFO polyvalent antiserum. O12 might still be present. Animals were immunized with vegetative and L-forms of S. typhi and the immune sera obtained were examined with the agglutination test. The liters of anti-L-form serum were much lower than these of anti-vegetative...

In this article, O antigens of Salmonella typhi H901 L-forms were tested with monovalcnt and AFO polyvalent antisera. No O9 anti-gen specific for S. typhi was found with monovalent antiserum on S. typhi H 901 L-forms, and L-forms could react but weakly with AFO polyvalent antiserum. O12 might still be present. Animals were immunized with vegetative and L-forms of S. typhi and the immune sera obtained were examined with the agglutination test. The liters of anti-L-form serum were much lower than these of anti-vegetative forms when tested with O and H antigen (P<0.01,P<0.001). Cross absorption tests were made with two antigen-antibody pairs. Vegetative forms could absorb all antibodies from the anti-L-form serum, but not in the reverse way. It indicates that there are still some O antigens left.

本文用因子血清检查伤寒杆菌H901株细菌型及L型的抗原结构,结果细菌型除Vi抗原缺失外,O和H抗原均完整;L型O_9抗原检测不出,但与AFO多价血清呈弱阳性,可能另有少量其他O抗原,如O_(12)抗原存在,H抗原仍保留不变。以伤寒杆菌L型和细菌型分别免疫家兔,将所获得的免疫血清与其相应的H与O抗原进行试管凝集1试验,结果L型免疫血清的O抗体及H抗体的凝集效价较细菌型的低(P<0.01,P<0.001),表明L型的抗原性降低。用L型抗原与细菌型免疫血清以及用细菌型抗原与L型免疫血清进行交叉凝集试验,两者之间有一定交叉凝集。而交叉凝集吸收,则见细菌型抗原能吸收掉L型免疫血清中全部的抗体,L型抗原却只能吸收细菌型免疫血清中部分抗体。

62 cases of gastrointestinal tumor were studied byimmuno--histochemial technique with a panel ofmonoclonal antibodies, in order to explore the expres-sion of major histocompatibility (MHC) antigens(HLA--ABC&DQ)on tumor cells and its relation-ship to tumor's bo~ behavior and localinfiltrating mononuclear cell subsets, It showed that in7/26 cases of gastric cancer, 5/36 cases of colorectal can-cer and 5/15 cases of lymph node metastasis ofgastrointestinal cancer, most or all of the tumor cells intissue section...

62 cases of gastrointestinal tumor were studied byimmuno--histochemial technique with a panel ofmonoclonal antibodies, in order to explore the expres-sion of major histocompatibility (MHC) antigens(HLA--ABC&DQ)on tumor cells and its relation-ship to tumor's bo~ behavior and localinfiltrating mononuclear cell subsets, It showed that in7/26 cases of gastric cancer, 5/36 cases of colorectal can-cer and 5/15 cases of lymph node metastasis ofgastrointestinal cancer, most or all of the tumor cells intissue section didn't express HLA--ABC antigen. In9/26 cases of gastric cancer, 8/36 cases of colorectalcancer and 6/15 cases of lymgh node metasis, someorall of the tumor cells expressed HLA--DR antigen,but HLA--DQ antigen was expressed only on a fewtumor cells in two cases of the DR tumors.Furthermore, the loss frequency of HLA--ABCantigen was much higher in early/small tumors(60%)than in advanced ones(15.79%). Expression of HLAantigens of gastrointestinal tumor were correlated to theextent of local infiltrating mononuclear cell subsets to acertain extent hese results suggest that MHC antigensmay play an important immune regulation role inoncogenesis and progression of gastrointestialcarcinoma.

利用一组单克隆抗体对62例胃肠癌组织进行免疫组化研究。结果发现:HLA-ABC抗原缺失率在胃癌,结、直肠癌和局部淋巴结转移灶分别为26.92%、13.89%和33.33%;HLA-DR抗原表达率分别为34.62%、22.22%、和40.0%,而HLA-DQ抗原仅表达于2例HLA-DR胃癌的少数癌细胞。且HLA-ABC抗原缺失率在早期癌(60.0%)明显高于中晚期癌(15.79%);胃肠癌的HLA抗原表达与局部单个核细胞各亚群浸润的程度间也有一定的相关。这些发现提示HLA抗原可能在肿瘤发生发展过程中具有重要的免疫调节功能。

Two cases of multiple primary carcinoma are reoprted. The first patient had six carcinomas in various sites of the colon as weal as in the urinary tract in a period of twelve years. In the other patient, within three years three carcinomas developed in the colon and the uterus. Observations on the chromosomal behavior in the lymphocytes of peripheral blood and ABO(H) antigens of the tumors of these patients revealed that: there were aberrations both in number and structure of the chromosomes; there was defect...

Two cases of multiple primary carcinoma are reoprted. The first patient had six carcinomas in various sites of the colon as weal as in the urinary tract in a period of twelve years. In the other patient, within three years three carcinomas developed in the colon and the uterus. Observations on the chromosomal behavior in the lymphocytes of peripheral blood and ABO(H) antigens of the tumors of these patients revealed that: there were aberrations both in number and structure of the chromosomes; there was defect in immunological function;and deletion of ABO(H) antigens in these tumors. These abnormal findings suggest that successive development of tumors in the same patients might possibly be related to defect in the immunological surveillance and instability of genetic substance.

以细胞遗传学及免疫组织化学方法,系统观察2例多原发癌病人。1例于12年内在结肠不同部位及泌尿系统发生6次癌,另1例于3年内在结肠及子宫等发生3次癌,2例均死于癌复发及全身衰竭。其外周血淋巴细胞染色体及癌组织中ABO(H)血型抗原观察表明:染色体数目及结构畸变率较高(P<0.01);免疫功能低下,癌组织切片中ABO(H)血型抗原缺失;提示多原发癌的发生可能与免疫功能缺陷、遗传物质的不稳定性有关,作者对此进行了讨论。

 
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