|
|
|
|
 |
|
|
|
|  | | 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。 | |
9-O-methylfusarubin was isolated from a novel source, Fusarion oxysporum, and evaluated for its phytotoxic and chlorotic inducing properties in plants as well as its potential as an antineoplastic agent.
|
| 例句来源 | |
Pemetrexed disodium is an antifolate antineoplastic agent that exerts its action by disrupting folate-dependent metabolic processes essential for cell replication.
|
| 例句来源 | |
Adriamycin (doxorubicin) is a potent and broad-spectrum antineoplastic agent, the clinical utility of which is limited by the development of a cumulative and irreversible cardiomyopathy.
|
| 例句来源 | |
Doxorubicin (DOX, Adriamycin?) is a potent antineoplastic agent used to treat a number of cancers.
|
| 例句来源 | |
Cis-diammine dichloro platinum (II) (CDDP), is a highly potent antineoplastic agent that is used in the treatment of ovarian cancer.
|
| 例句来源 | | 更多 |
|
Background: Ecteinascidin-743 (ET743) is a novel antitumour agent originating from the Caribbean tunicate Ecteinascidia turbinata.
|
| 例句来源 | |
N-Methylformamide (NMF), currently under-going phase II clinical evaluation for the treatment of cancer, and the established antitumour agent cis-platinum (CDDP) have nonoverlapping toxicities, with the exception of gastrointestinal side effects.
|
| 例句来源 | |
Although the antitumour agent flavone-8-acetic acid (FAA) exhibits remarkable activity against murine solid tumours, its clinical use has a number of pharmacological drawbacks, including low dose potency and dose-dependent pharmacokinetics.
|
| 例句来源 | |
N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (AC) is an experimental antitumour agent that is being considered for phase I trials.
|
| 例句来源 | |
Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis
|
| 例句来源 | | 更多 |
|
|
|

| | The chicken anemia virus protein apoptin induces a p53 independent, bcl 2 insensitive type of apoptosis in various human tumor cells but not in human normal cells. These properties make apoptin a potential anti tumor agent. The purpose of this review is to summarize the characteristics of apoptin induced apoptosis and to discuss the molecular mechanism by which apoptin induces tumor cell apoptosis. | | 来源于鸡贫血病毒(CAV)的凋亡素(Apoptin) 能够选择性地诱导肿瘤细胞凋亡,且不依赖于p53 介导,对bcl-2 过表达不敏感的特点,使其成为一种非常有前景的抗肿瘤剂。该文介绍了凋亡素诱导细胞凋亡的作用特点,并对其凋亡选择性诱导研究的分子机制进行了探讨。 | | 文摘来源 | | The effect of PIC BE,a kind of water soluble derivative of | | β榄香烯吗素(PIC-BE)是抗癌新药β榄香烯的水溶性衍生物.采用人红白血病的多药耐药性(MDR)细胞株K562/ADM作为实验模型,观察PIC-BE对K562/ADM细胞的生长抑制和凋亡诱导作用,并进而研究其对该细胞MDR的可能影响.结果显示:(1)K562/ADM细胞对ADM具有明显的抗性,与K562细胞相比,抗性倍数约为40倍,而两者对PIC-BE的IC50接近,无显著差异;(2)PIC-BE(10.0~30.0μg/ml)对K562/ADM细胞具有明显的生长抑制和凋亡诱导作用,两种作用的强度在一定的范围内均具药物浓度和作用时间依赖性;(3)低毒剂量PIC-BE(10.0μg/ml)与ADM(4.0μg/ml)联合应用,可显著增强ADM对该细胞的生长抑制和凋亡诱导作用,升高细胞内ADM的浓度,降低该细胞对ADM的IC50,使该细胞对ADM的抗性有数倍逆转.上述结果提示,PIC-BE不仅是一种有效的广谱抗肿瘤剂,而且也是一种有效的MDR逆转剂 | | 文摘来源 | | Objective To investigate whether gensenoside Rg1 could induce apoptosis of murine melanoma cells in vitro, and to observe the effect on cell viability when those cells were exposed to both gensenoside Rg1 and anti neoplastic(MeCCNU). Methods The morphological and ultrastructural changes of the cells treated with gensenoside Rg1(100μ mol/L) for 3 or 72 hours were examined by transmission electron microscopy(TEM) and double- fluorescent staining with acridine orange and ethidium bromide. Meanwhile, flow cyt... | | 目的 观察人参皂甙 Rg1在体外能否诱导鼠黑素瘤细胞发生凋亡 ,与抗肿瘤剂甲环亚硝脲( MeCCNU)联合处理细胞时对细胞存活率的影响。方法 用荧光染色技术和透射电镜技术观察药物作用后的细胞形态和超微结构改变,并用流式细胞术和 MTT比色法测定药物对细胞生长周期、凋亡细胞诱导率以及细胞存活率的影响。 结果 经 AO/EB双重荧光染色和超微结构显示 100μ mol/L人参皂甙 Rg1作用 72 h能使部分体外培养细胞发生典型的凋亡细胞的形态改变。人参皂甙 Rg1与甲环亚硝脲以 3种不同处理方式处理细胞的凋亡细胞诱导率以联合处理组最高 (61.75% ),并无细胞周期选择性。 MTT比色法测定细胞存活率结果提示人参皂甙 Rg1单独处理细胞时本身未见明显细胞毒性,但与 MeCCNU联合处理却能大大加强后者对黑素瘤细胞的细胞毒性。 结论 人参皂甙 Rg1联合甲环亚硝脲在体外能以非细胞周期选择方式诱导部分黑素瘤细胞凋亡,推测这一作用可能与人参皂甙的抗肿瘤作用相关。 | | 文摘来源 | |   | | << 更多相关文摘 |
|
相关查询: | |
对查询结果不满意
|
|
|
|