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  carcinoma
    Nasopharyngeal Carcinoma Related Genes and Their Single Nucleotide Polymorphisms Screened out from 6p21.3
    6p21.3区域鼻咽相关基因及其单核苷酸多态性
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    Scanning and Preliminary Functional Analysis of Nasopharyngeal Carcinoma Related Genes on Chromosome 3p21-22
    染色体3p21-22区域鼻咽相关基因的筛选及其功能的初步研究
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    Preliminary Studies of Genetic Susceptibility and Susceptible Genes of Nasopharyngeal Carcinoma
    鼻咽遗传易感性及其易感基因的初步研究
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    Molecular Cloning and Function Analysis of a Novel Gene Associated Nasopharyngeal Carcinoma on Chromosome 3p21
    染色体3p21区域鼻咽相关新基因的克隆及其功能研究
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    The Application Study of Cerebral MR Perfusion Imaging on Radiation-induced Injury Following Radiotherapy for Nasopharyngeal Carcinoma
    MR脑灌注成像在鼻咽放疗后放射性脑损伤中的应用研究
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  cancer
    An Effect-evaluation Study of the Screening for Nasopharyngeal Cancer
    鼻咽疾病史模型,筛查过程模拟及筛查方案优化研究
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    CLINICAL ANALYSIS ON NASOPHARYNGEAL CANCER ASSOCIATED WIH MUL TIPLE PRIMARY TUMORS-A REPORT OF 160 CASES
    鼻咽与多发160例临床分析
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    The Relationship Between the Phenotype of Tumor Infiltrating Cells and the Prognosis in Laryngeal Cancer
    喉周浸润细胞的表现型和临床预后的关系
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    Serologic screening on Nasopharyugeal Cancer in 338 868 Persons in 21 Cities and Counties of Guangxi Region,China
    广西21市县338868人鼻咽血清学普查
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    The influence of cervical cervical incisional biopsy of nasopharyngeal cancer(NPC)on prognosis
    鼻咽颈部淋巴结转移切取活检对其预后的影响
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  carcinomas
    The Expression of VEGF-C,VEGFR-3 and NF-κ B p65 in Human Laryngeal Squamous Cell Carcinomas and Its Relationship with the Lympatic Nodes Metastesis
    VEGF-C、VEGFR-3和NF-κB在喉鳞状细胞中的表达及其与淋巴结转移的关系
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    Genetic Polymorphisms in DNA Repair Genes and Risks of Laryngeal & Hypopharyngeal Carcinomas
    DNA修复基因遗传变异与喉喉咽风险
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    Gene Expression Analysis and Prognostic Significance of Stefin A and Cathepsin B in Laryngeal Squamous Cell Carcinomas
    Stefin A和cathepsin B基因在喉鳞状细胞中的表达差异分析以及同临床预后的关系
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    Transcriptomic Abnormalities Associated with Recurrence and Metastasis in Laryngeal Squamous Cell Carcinomas
    转录组异常改变与喉鳞复发转移的研究
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    The Gene Expression Study of the Epithelial Membrane Protein 1 and Matrix Mettallo-proteinases in Laryngeal Squamous Cell Carcinomas and Clinical Applications
    EMP_1和MMP_s基因在喉鳞状细胞中的表达差异分析及临床应用探讨
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  “癌”译为未确定词的双语例句
    Researches of Green Tea (Polyphenoles) and Oxymatrine on the Multidrug Resistance and Reversal Mechanism in HNE-1 Cell Line
    天然药物氧化苦参碱、绿茶多酚对鼻咽HNE-1细胞耐药逆转研究
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    Study of Nasopharyngeal Anatomy Concerning Clinical Dosemetry of Radiation Treatment
    鼻咽放射治疗相关解剖及临床剂量学研究
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    ORBITAL METASTASIS—REPORT OF 5 CASES
    眼眶转移—附5例报告
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    The Expression of HLA, Epstein-Barr Virus Nuclear Antigen and the Infiltration of T Lymphocyte Subsets in Nasopharyngeal Biopsy Tissues
    鼻咽活检组织中HLA、EBNA及间质中T淋巴细胞亚群的分布
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    The effect of laryngopharyngectomy on thyroid function
    喉下咽手术对甲状腺功能的影响
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  carcinoma
Immunohistochemical analysis revealed a high expression level of hSef in kidney, testis, and the corresponding carcinoma tissues.
      
Effect of down-regulating VEGF on proliferation of colon carcinoma cell HT-29
      
Cancer-related genes harbored in the loss regions containing a high frequency of hepatocellular carcinoma (HCC) were selected.
      
The purified 19peptide directly inhibited proliferation and migration of murine B16 melanoma cells, SMMC-7721hepatoma carcinoma cells and human umbilical vein endothelial cells (HUVEC).
      
We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
      
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  cancer
Guanidine-like compounds have been investigated since the first observations of their therapeutic potential some 30 years ago in fields of cancer and virology.
      
Epidermal Growth Factor Receptor (EGFR) is among the growth factor receptor kinases that have been implicated in as being important in cancer.
      
Inhibitive Effect of Prodigiosin on the Proliferation of Human Malignant Pancreatic Cancer Cells
      
Pancreatic cancer is not only common, but also extremely difficult to treat, for which it has been called "the challenge of the twenty-first century".
      
In this study, we find that prodigiosin could effectively inhibit the proliferation of human pancreatic cancer cells H8898 in a dose-and-time-dependent manner, with an IC50 of 75μmol according to the results of MTT and cell proliferation assays.
      
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  carcinomas
It is difficult to distinguish a rectal carcinoma with anal metastases from coexistent synchronous anorectal carcinomas.
      
Loss of heterozygosity of a segment at 3p21.3 is frequently observed in lung cancer and several other carcinomas.
      
Downregulation of genes encoding for subunits of adaptor complex-3 in cervical carcinomas
      
Expression of this gene in invasive carcinomas was maintained on a definite level that was not significantly distinct from that in adjacent normal (control) tissue.
      
Among the 50 carcinomas, 11 (22%) showedAlu-VpA/MycL1 instability, and 14% (6/43 informative) had lost theAlu-VpA/MycL1 allele.
      
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Xeroderma pigmentosum (XP) is anexceedingly rare disease, which isautosomal recessive genetically, chron-ically progressive and multisystemicwith the skin as the major targetorgan. The eyes are often involved.The characteristics of XP, just asGrindon described, are "a rare, chron-ic, fatal disease, beginning in infan-cy, characterized by freckking,atrophic stops, telangiectasis andkeratosis, and later by the developmentof carcinomata and sarcomata." Thesesigns usually occur at a very early age.The Desanctis-Cacchione...

Xeroderma pigmentosum (XP) is anexceedingly rare disease, which isautosomal recessive genetically, chron-ically progressive and multisystemicwith the skin as the major targetorgan. The eyes are often involved.The characteristics of XP, just asGrindon described, are "a rare, chron-ic, fatal disease, beginning in infan-cy, characterized by freckking,atrophic stops, telangiectasis andkeratosis, and later by the developmentof carcinomata and sarcomata." Thesesigns usually occur at a very early age.The Desanctis-Cacchione syndrome isthe most severe form of XP. In additionto the skin lesions, the syndromeconsists of microcephaly with mentaldeficiency premature closure of thesutures retarded growth and sexualdevelopment choreoathetosis, cerebellarataxia eventual quadriparesis withshortening of the achilles tendons andsometimes sensorineural deafness. In this paper seven patients withXP seen in last 20 years in GeneralHospital, Sichuan Medical College arepresented. Three were in-patients andfour out-patients. Besides the skinlesions in exposed regions, ocularaffections were seen in all the patients,especially on the skin of eyelids. Theyappeared often early and were severe.The conjunctiva and orbits might besimultaneously involved. Biopsy wasperformed on six patients and malign-ancies were confirmed in five. Theyall were proved to be either basal cellcarcinoma or squamous cell carcinoma,except one case of orbital malignantmelanoma. The onset of XP occurs most com-monly in early childhood. Five patientshad their onsets before the age of 3. Inthis series the youngest one had the ill-ness at the age of 6 months. The oldestcase had his onset at the age of 13,and he got cancer at 16. The patientdied 17 years after the discovery ofthe malignancy. The relatively lateonset and long survival of the patientmight be due to the optimal remedieshe had received. This was a ratherrare case in XP. The occurrence of this disease iscommonly seen in summer and spring.In this series four occurred in summertwo in spring, and one obscure. Skinlesions have a predilection for theexposed parts of the body in typicalcases.But one patient in this series hadcutaneous changes all over the bodyincluding freckles and white flecks onthe skin of the buttocks, scrotum penisand inner and outer surface of thethighs. Seven patients in this series camefrom 5 families. The development ofXP is closely related to heredity,especially consanguineous marriage of parents or grand-parents. In 2 of thefamilies, the patients' parents weremarried in sibship, and in one of therest 3 families there were 2 or 3 mem-bers suffering from XP simultaneously.Cases 4 and 5 were sib brother andsib sister and in their family 4 of 5siblings had similar clinical manifes-tations. Case 5 was an advanced patientclinically but biopsies of skin of theforearm and bulbar conjunctiva failedto reveal malignant change. Nothingabnormal was discovered by karyotypeexamination in 3 cases. In 1968, JE Cleaver demonstratedthat the main biochemical defect wasthe failure of excision-repair of ultra-violet (UV) damage of DNA in fibro-blasts in the skin of patient with XP.This aberration was believed to beassociated with the UV-endonucleasethat initiates excision. Subsequentstudies suggested that XP might involveenzymatic defects in more than onesystem. Lynch reported an eight-yearfollow up a pair of 16 year-old identi-cal twin brothers. Histological findingsfrom skin biopsy of each twin werefound consistent with XP. But theyhad been assiduously protected fromsolar radiation since birth. They didnot develop any evidence of skincancer. The prognosis of this disease isbad. All the patients have a tend todevelop canceration at the advancedstage. Lynch indicated that malignantskin tumors, most commonly basal andsquamous cell carcinomas, occurred inparticular all of the patients at a veryearly age. Malignant melanoma occurredin at least 3% of these patients. Pa-tients with XP usually died within thefirst two decades of their lives due tometastasis from the malignant skintumors In this series, 5 patients with XPdeve

本文报告7例着色性干皮病,该病除皮肤损害外,均合并有眼部病变。6例经病理检查证实有变者5例,其中以基底细胞和鳞状上皮为多,仅1例为眼眶恶性黑色素瘤。作者对本病的好发部位、发病年龄和季节进行了分析,并着重对本病的发病机理、遗传因素以及变和预防措施等问题,进行了简要的讨论。

55 Patients were treated by liquid nitrogen cryosurgery of the lids and conjunctiva diseases. 28 patients With eyelids angioma, 5patients conjunctiva angioma, 4 patients with basal cell carcinoma, 2 patients with squamous cell carcinoma,2patients with meibomian carcinoma, 2 patients precancerous melanosis; and 6 patients with spring catarrh. Forty-seven patients were followed-up, and the average duration was 28 months(range 18~48 months),All cases obtained extremely good results with cryosurgery and without...

55 Patients were treated by liquid nitrogen cryosurgery of the lids and conjunctiva diseases. 28 patients With eyelids angioma, 5patients conjunctiva angioma, 4 patients with basal cell carcinoma, 2 patients with squamous cell carcinoma,2patients with meibomian carcinoma, 2 patients precancerous melanosis; and 6 patients with spring catarrh. Forty-seven patients were followed-up, and the average duration was 28 months(range 18~48 months),All cases obtained extremely good results with cryosurgery and without serious complications.

本文介绍55例液氮冷冻治疗眼病的患者,其中眼睑血管瘤28例,结膜血管瘤5例,基底细胞4例,鳞形细胞2例,睑板腺2例,黑色素痣前期2例,春季卡他性结膜炎6例,疗效满意,无严重并发症,值得推广。

NPC with eye signs and symptoms is very common because of the close anatomical relation between nasopharynx and the orbit and cranial nerves. In this paper we reviewed 510 cases of NPC in our hospital, of which 81 patients (15.88%) presented ophthalmologic signs and symptoms. The most common symptom is diplopia caused by paralysis of the 6th cranial nerve (73 cases, 90%). 56 patients (69%) showed eye pain accompanied with headache, 36 cases (44.4%) had unilateral ptosis, 28 cases (34.6%) decreased visual acuity...

NPC with eye signs and symptoms is very common because of the close anatomical relation between nasopharynx and the orbit and cranial nerves. In this paper we reviewed 510 cases of NPC in our hospital, of which 81 patients (15.88%) presented ophthalmologic signs and symptoms. The most common symptom is diplopia caused by paralysis of the 6th cranial nerve (73 cases, 90%). 56 patients (69%) showed eye pain accompanied with headache, 36 cases (44.4%) had unilateral ptosis, 28 cases (34.6%) decreased visual acuity or blindness, 18 cases (22.2%) proptosis, 11 cases (13.6%) Horner's syndrome, 18 cases (22.2%) had a combined paralysis of the 3rd, 4th, 5th and 6th cranial nerves, the so called cavernous sinus syndrome. 14 cases (17.3%) had paralysis of the 2nd, 3rd, 4th, 5th and 6th cranial nerves with proptosis, the so called orbital apex syndrome. In 2 cases (2.46%) decreased visual acuity or blindness caused by the 2nd cranial nerve invasion first and then was followed by paralysis of the 3rd, 4th, 5th, 6th cranial nerves, the so called pituitary-sphenoidal bone syndrome.

鼻咽是中国特别是南方常见的瘤,由于鼻咽与眼眶和颅神经在解剖部位上有毗邻的联系,因此鼻咽合并有眼部症状及体征者很常见,而且常常为主要症状就诊于眼科。本文报告中山医科大学附属肿瘤医院1964年3月至1965年8月以及1985年3月至8月共检查住院鼻咽病人510例合并有眼部症状81例,占15.88%。眼部症状以第Ⅵ对颅神经损害引起复视最为常见,81例中占73例(90%),而且较早出现;其次为眼痛合并头痛56例(69%),上睑下垂36例(44.4%),视力下降或失明28例(34.6%),突眼18例(22.2%),何纳氏综合征11例(13.6%)。同时合并第Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害符合海绵窦综合症18例 (22.2%);同时合并第Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害并有突眼符合眶尖综合症14例(17.3%);先有视力下降或失明的第Ⅱ对颅神经损害而后出现第Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害符合垂体—蝶骨综合征者2例(2.46%)。以眼部症状为主而去眼科诊治的24例(29.6%),常诊断为斜视、视网膜炎、球后肿瘤等。因此凡不明原因的眼肌麻痹、复视、失明、突眼、上睑下垂症状的患者,特别是...

鼻咽是中国特别是南方常见的瘤,由于鼻咽与眼眶和颅神经在解剖部位上有毗邻的联系,因此鼻咽合并有眼部症状及体征者很常见,而且常常为主要症状就诊于眼科。本文报告中山医科大学附属肿瘤医院1964年3月至1965年8月以及1985年3月至8月共检查住院鼻咽病人510例合并有眼部症状81例,占15.88%。眼部症状以第Ⅵ对颅神经损害引起复视最为常见,81例中占73例(90%),而且较早出现;其次为眼痛合并头痛56例(69%),上睑下垂36例(44.4%),视力下降或失明28例(34.6%),突眼18例(22.2%),何纳氏综合征11例(13.6%)。同时合并第Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害符合海绵窦综合症18例 (22.2%);同时合并第Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害并有突眼符合眶尖综合症14例(17.3%);先有视力下降或失明的第Ⅱ对颅神经损害而后出现第Ⅲ、Ⅳ、Ⅴ、Ⅵ颅神经损害符合垂体—蝶骨综合征者2例(2.46%)。以眼部症状为主而去眼科诊治的24例(29.6%),常诊断为斜视、视网膜炎、球后肿瘤等。因此凡不明原因的眼肌麻痹、复视、失明、突眼、上睑下垂症状的患者,特别是广东籍人应该排除鼻咽之可能。鼻咽出现眼症已属晚期,预后较差。

 
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