The area of Corpora Cavernosa smooth muscle , collagen fiber and Cavernous sinus lacuna of the Corpus Cavernosum of the rats penis and the content of the eNOS expressed in the Corpus Cavernosum of the rats penis, stained with Masson's and immunohistochemistry method respectixely, was measured under the optical microscope with Miass computer configuration image analysis system.
Conclusions: YKJN can improve the sexual activity ability of the erectile dysfunction of depression of Liver-Qi model animals, the mechanism of which may be related with declining the omni-blood viscosity, anti-hyperplasia of the collagen of penis Corpora Cavernosa and activating the NO-cGMP pathway to regulate the relaxation of penis Corpora Cavernosa smooth muscle.
Conclusion Ganyuqizhi may decrease the nNOS activityand Chinese herb of Shuganlieyuxingqihuoxue may increase NOS activity in corpora cavernosa of penis.
Results The nNOS activity ofGanyuqizhi model group is lower than that activity of normal group(P<0.01)and the nNOS activity of Chinese herbgroup is higher than that of Ganyuqizhi group(P<0.05).
6. Model group. To observe the effect on the serum blood sugar, blood rheologic index, baccharificating hemoglobin, sexual hormon, blood fat and influence on some other indexes of rat's corpus songiosum penis smooth muscles, such as: iNOS, Bax, Bcl-2, TGF- P ,, CPP32, ? -SMA, PDE5 expression with the formula of tonifying the kidney and circulating blood.
3. The formula of tonifying the kidney and circulating blood can reduce the amount of collagen in corpus songiosurn penis tissue, increase the amount ofsmooth muscle cells.
Conclusion: The formula of tonifying the kidney and circulating blood possessthe better function on Inhibiting corpus songiosum penis cells death, protectingcorpus songiosum smooth muscle cells from destoring, inhibiting collagen fibersproliferation and it's efficiency is better than Dornei Kang and Dameikang withAnxiong.
Because NO is a short-lived molecule whose level can not easily be measured, NO activity is commonly estimated by measuring levels of nitric oxide synthase ( NOS ) and its enzyme activity.
Phosphodiesterase (PDE) 5 inhibitors reduce cyclic guanylate monophosphate breakdown, promoting vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation.
This review suggests crural corpora cavernosa as the graft of choice, because it more closely resembles the incised area both anatomically and functionally.
More than half of these intraoperative complications occur during dilatation of the corpora cavernosa.
Dilation of the corpora cavernosa is a critical step in the placement of any type of penile prosthesis and can be especially difficult in a patient with corporal fibrosis.
In response to sexual stimulation, sildenafil effectively potentiates the natural dilatation of arteries supplying blood to the penis and corpora cavernosa.
Objectives: To study the PDE5 activity in corpora cavernosa of the Ganyu Qizhi model penis and the efffect of the Chinese herbal medicine Shugan Liqi Huoxue (SLH) ointment on it. Methods: Non-injury stress stimulus method similar to human spirit stress was used to extablish the Ganyu Qizhi animal(rat) model, and the PDE5 activity in corpora cavernosa of the rat penis was measured by the method of immunohistochemistry and computer image analysis. Results: The PDE5 activity in corpora cavernosa of the high-dosage...
Objectives: To study the PDE5 activity in corpora cavernosa of the Ganyu Qizhi model penis and the efffect of the Chinese herbal medicine Shugan Liqi Huoxue (SLH) ointment on it. Methods: Non-injury stress stimulus method similar to human spirit stress was used to extablish the Ganyu Qizhi animal(rat) model, and the PDE5 activity in corpora cavernosa of the rat penis was measured by the method of immunohistochemistry and computer image analysis. Results: The PDE5 activity in corpora cavernosa of the high-dosage SLH group was significantly different from that of the model group (P< 0.01). Conculsion: Ganyu Qizhi may increase the PDE5 activity in corpora cavernosa of the penis while SLH can reduce such activity.
AIM:To study the massage to pelvic organs altering the status of penile blood flow and the different effects on penile blood flow by massaging different organs of pelvic kidney. METHDS:The peak systolic velocity(PSV), end diastolic velocity(EDV) and resistant index(RI) of right lateral cavernosal arteries were evaluated and obtained in 10 healthy volunteers with color doppler ultrasonography respectively at three distinct phases:sedentary condition,rectal massage and prostate massage. RESULTS:The PSV,EDV...
AIM:To study the massage to pelvic organs altering the status of penile blood flow and the different effects on penile blood flow by massaging different organs of pelvic kidney. METHDS:The peak systolic velocity(PSV), end diastolic velocity(EDV) and resistant index(RI) of right lateral cavernosal arteries were evaluated and obtained in 10 healthy volunteers with color doppler ultrasonography respectively at three distinct phases:sedentary condition,rectal massage and prostate massage. RESULTS:The PSV,EDV and RI of right cavernosal arteries in 10 health subjects were(8.86±3.19)cm/s,(1.13±0.49)cm/s and 0.87±0.06 scanned before massaging rectal walls and prostate glands,(9.21±3.65) cm/s,(1.69±0.64)cm/s and 0.78±0.14 at the phase of massaging rectal walls and(18.96±6.47)cm/s,(2.60±1.22)cm/s and 0.86±0.05 at the phase of massaging prostate.The increase of EDV during massaging to rectal walls showed statistical significance(t=2.32,P=0.046),whereas, rectal massage did not alter PSV significantly(t =0.29, P=0.78).Both PSV and EDV increased markedly at massage to prostate phase and showed statistical significance(t=3.89 and 3.92,Both P=0.004).Seven out of 10 subjects presented penile tumescence during prostate massages but no full penile erection was observed. CONCLUSION:The obviously increase of EDV of cavernosal arteries was scanned during massages on rectal walls.The massages to prostates can obviously cause the increase of both PSV and EDV.It was found that the effects on penile blood flow varied with the stimulation to distinct pelvic organs.It is postulated that a certain nerve reflex may be involved in the phenomena observed in the present study.
Objective To research the NOS activity in corpora cavernosa of Ganyuqizhi model penis and theefffect of Chinese herb of Shuganliqi on it. Methods Utilizing non-traumatic stress stimulus method which similar tospirit stress of human,to set up Ganyuqizhi animal (rat) model,and NOS activity in corpora cavernosa of rat penis wasmeasured by the method of immunohistochemistry and computer image analysis. Results The nNOS activity ofGanyuqizhi model group is lower than that activity of normal group(P<0.01)and...
Objective To research the NOS activity in corpora cavernosa of Ganyuqizhi model penis and theefffect of Chinese herb of Shuganliqi on it. Methods Utilizing non-traumatic stress stimulus method which similar tospirit stress of human,to set up Ganyuqizhi animal (rat) model,and NOS activity in corpora cavernosa of rat penis wasmeasured by the method of immunohistochemistry and computer image analysis. Results The nNOS activity ofGanyuqizhi model group is lower than that activity of normal group(P<0.01)and the nNOS activity of Chinese herbgroup is higher than that of Ganyuqizhi group(P<0.05). Conclusion Ganyuqizhi may decrease the nNOS activityand Chinese herb of Shuganlieyuxingqihuoxue may increase NOS activity in corpora cavernosa of penis. Maybe it is animportant pathological factor to form psychological erectile dysfunction .
阴茎海绵体
cavernosa
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