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   重型地中海贫血 的翻译结果: 查询用时:0.783秒
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重型地中海贫血
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  thalassemia major
     SCREENING OF THALASSEMIA MAJOR IN CORD BLOOD BY PEPTIDE CHAIN ANALYSIS
     脐血肽链分析筛查重型地中海贫血研究
短句来源
     Objectives To evaluate the early diagnosis way of thalassemia major.
     评价重型地中海贫血 (地贫 )的早期诊断方法。
短句来源
     Treatment of thalassemia major with unrelated donor bone marrow transplantation
     非血缘相关骨髓移植治疗重型地中海贫血的临床研究
短句来源
     Abstract:One hundred and twenty children with thalassemia major were treated with gelfoam particales for partial splenic embolization (PSE).
     采用大部分牌动脉栓塞(PSE)治疗重型地中海贫血120例,病儿全部成活,巨牌均显著缩小,贫血较明显改善,抗感染能力增加。
短句来源
     Objective To explore the role of Fludarabine (FDR) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) for class 3 thalassemia major with regard to regimen toxicity, graft regection,disease recurrence and disease-free survivals (DFS).
     目的 观察以“氟达拉宾”为主的预处理在异基因造血干细胞移植治疗Pesaro Ⅲ级重型地中海贫血的预处理毒性、移植排斥、复发及长期无病生存情况。
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  β-thalassemia major
     Bone marrow transplantation for β-Thalassemia major
     骨髓移植治疗重型地中海贫血
短句来源
     Objective To investigate the feasibility of bone marrow hematopoietic stem cell transplantation in treating β-thalassemia major.
     目的探讨骨髓移植治疗重型地中海贫血的可行性。
短句来源
     Results: 14 patients withβ-thalassemia major, 7 patients withβ-thalassemia minor and 3 patients withβ-thalassemia combined with HbE were diagnosed . 10 kinds of gene mutations were identified among these patients.
     结果:24例患儿中重型地中海贫血14例,βE3例,轻型7例,发现10种基因突变类型。
短句来源
  “重型地中海贫血”译为未确定词的双语例句
     Nursing Care of Erythrocyte Suspension in Combination with Deferoxamine Transfusion in the Treatment of β-thalasse-mia
     红细胞悬液联合得斯芬治疗β重型地中海贫血患儿的护理
短句来源
     Immunologic function of children with severe mediterranean anemia after partial splenic embolization
     大部脾栓塞术对重型地中海贫血患儿免疫功能影响的研究
短句来源
     THE SIGNIFICANCE OF HEALTH EDUCATION FOR THE FAMILY OF PEDIATRIC PATIENTS WITH ADVANCED MEDITERRANEAN ANEMIA
     对重型地中海贫血患儿家庭健康教育的意义
短句来源
     Second transplantation using allogeneic bone marrow from parents for beta-thalassaemia major patients after graft failure
     HLA部分相合父母供髓骨髓移植二次治疗重型地中海贫血
短句来源
     Results showed that serum EPO and sTfR levels in β thalaseemia major patients were significantly higher than those in normal control group, and no significant difference in β thalassemia minor cases with those in control.
     结果显示 ,β 重型地中海贫血患者血清EPO和sTfR水平均明显高于正常对照组 (P <0 .0 5) ,而轻型患者与正常人无显著差别。
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  thalassemia major
This study explores the psychosocial problems experienced by families with children aged 6 to 14 years suffering from β-thalassemia major (N=188).
      
In order to identify the distribution of gene types of β-thalassemia and reduce the birthrates of β-thalassemia major in Guiyang area, 1054 pregnant women and their spouses from Affiliated Hospital, Guiyang Medical College were screened.
      
Among the 4 cases subject to prenatal gene diagnosis, one fetus was completely normal and 3 fetuses were diagnosed as having β-thalassemia major (1 homozygous and 2 compound heterozygous).
      
The fetuses diagnosed as β-thalassemia major were selectively terminated within two weeks.
      
It was concluded that the birthrate of β-thalassemia major in Guiyang area was reduced and the target of improving birth outcome and child development has been achieved.
      
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  β-thalassemia major
This study explores the psychosocial problems experienced by families with children aged 6 to 14 years suffering from β-thalassemia major (N=188).
      
In order to identify the distribution of gene types of β-thalassemia and reduce the birthrates of β-thalassemia major in Guiyang area, 1054 pregnant women and their spouses from Affiliated Hospital, Guiyang Medical College were screened.
      
Among the 4 cases subject to prenatal gene diagnosis, one fetus was completely normal and 3 fetuses were diagnosed as having β-thalassemia major (1 homozygous and 2 compound heterozygous).
      
The fetuses diagnosed as β-thalassemia major were selectively terminated within two weeks.
      
It was concluded that the birthrate of β-thalassemia major in Guiyang area was reduced and the target of improving birth outcome and child development has been achieved.
      
更多          


Abstract:One hundred and twenty children with thalassemia major were treated with gelfoam particales for partial splenic embolization (PSE). After PSE, the large spleen strank greatly,the symptoms of anemia improved, and the ability against infection was even increases. The complications, for example, pneumonia in 2 cases, splenic abscess, adhesive liens, bleeding on place catheterizing via percutaneous femoral artery and blocking of respiratory passage caused by tongou's falling behind in one caase respectively....

Abstract:One hundred and twenty children with thalassemia major were treated with gelfoam particales for partial splenic embolization (PSE). After PSE, the large spleen strank greatly,the symptoms of anemia improved, and the ability against infection was even increases. The complications, for example, pneumonia in 2 cases, splenic abscess, adhesive liens, bleeding on place catheterizing via percutaneous femoral artery and blocking of respiratory passage caused by tongou's falling behind in one caase respectively. Occured in 6 of the patients.These complications subsided after treatment.

采用大部分牌动脉栓塞(PSE)治疗重型地中海贫血120例,病儿全部成活,巨牌均显著缩小,贫血较明显改善,抗感染能力增加。PSE后6例发生了并发症,肺炎2例,脾脓肿、粘连性肠梗阻、股动脉插管处大出血及舌后坠致气道梗阻各1例,经处理后均恢复。PSE必须严格无菌操作,栓塞范围不宜过大,以防脾脓肿发生。使用抗生素及镇痛剂,防止栓塞后因疼痛膈肌运动受限而并发肺炎。静脉麻醉药物剂量应注意个体差异,防止舌后坠,气道梗阻,术毕穿刺局部宜用绷带包扎,松紧应适度,预防大出血。术后数日应适当活动,防止并发粘连性肠梗阻。

Objective The purpose of this study was to assess the effect of partial splenic embolization (PSE) on immunologic function of patients with severe mediterranean anemia (SMA). Methods immunoglobulins were determined in 62 children with SMA before and after PSE. Also, lymphocyte subpopulation, lysozyme and fibronectin were measured in 40 cases. Results IgG was significantly lower one week after operation (12 8±4 3 g/L) than that before operation (16 2±5 5 g/L) ( P <0.05). It recovered three weeks...

Objective The purpose of this study was to assess the effect of partial splenic embolization (PSE) on immunologic function of patients with severe mediterranean anemia (SMA). Methods immunoglobulins were determined in 62 children with SMA before and after PSE. Also, lymphocyte subpopulation, lysozyme and fibronectin were measured in 40 cases. Results IgG was significantly lower one week after operation (12 8±4 3 g/L) than that before operation (16 2±5 5 g/L) ( P <0.05). It recovered three weeks after operation (15 8±5 1 g/L). Fibronectin was significantly higher after PSE (248±78 g/L) than that before PSE (118±41 g/L), but IgA, IgM and lysozyme levels remained unchanged during PSE. Total T, T helper lymphocytes (T H) and T H/T S ratio increased after PSE as compared with those before PSE ( P <0.01). Whereas, T suppressor lymphocytes (Ts) level remained unchanged during operation.Conclusion Immunologic function of children with SMA increased 3 weeks after PSE.

目的评估大部脾栓塞术后重型地中海贫血患儿免疫功能的变化。方法对62例患儿行脾大部栓塞术。结果IgG在术后1周(13±4g/L)和术前(16±6g/L)差异有显著意义(P<0.05),术后3周恢复术前水平(16±5g/L)。IgA、IgM术前及术后各周均无明显差异。T细胞亚群中总T细胞数术前(49±12)和术后(60±12)差异有非常显著意义(P<0.01)。T辅助淋巴细胞(TH)术前(38±9)与术后(45±7)比较差异有非常显著意义(P<0.01)。TH/TS比值术后(1.6±0.3)与术前(1.29±0.4)比较差异有非常显著意义(P<0.01),而T抑制淋巴细胞(Ts)术后(29±7)与术前(31±6)比较差异无显著意义(P>0.05)。纤维连接蛋白术后(248±78)与术前(118±41)比较差异有显著意义(P<0.05)。结论PSE后免疫功能在术后3周迅速恢复

Objectives To evaluate the early diagnosis way of thalassemia major. Methods Tricton polyacrylamide gel electrophoresis (TAU PAGE) of cord blood from newborns, gene analysis and following study were used. Results: of 2423 samples of cord blood, 10(0.41%) were found to have not α Chain and 7 (0.29%) have not β Chain. Not special fragment were found for all 7 Bart's hydrop fetus after digestion with Bam HI and BglⅡ. Typical clinical manifestation appeared in early life of all 7 β°thalassemia major. Their genetype...

Objectives To evaluate the early diagnosis way of thalassemia major. Methods Tricton polyacrylamide gel electrophoresis (TAU PAGE) of cord blood from newborns, gene analysis and following study were used. Results: of 2423 samples of cord blood, 10(0.41%) were found to have not α Chain and 7 (0.29%) have not β Chain. Not special fragment were found for all 7 Bart's hydrop fetus after digestion with Bam HI and BglⅡ. Typical clinical manifestation appeared in early life of all 7 β°thalassemia major. Their genetype is the most common type: 3 were CD 17/CD 17,2 were CD 17/CD 41 42, and 1 was CD 17/ IVSI 1. Conclusions It is reliable to screen early thalassemia major in newborn by TAU PAGE way, and It is important to treat early and improve prognosis to patients, to geretic counseling and to evaluate the effecting of thalassemia preventive program.

评价重型地中海贫血 (地贫 )的早期诊断方法。方法 :新生儿脐血聚丙烯酰胺凝胶电泳 (TAu- PAGE)、基因分析及随访调查。结果 :连续筛查新生儿脐血 2 42 3例 ,α链消失 10例 (0 .41% ) ,β链消失 7例 (0 .2 9% )。 10例 Hb Bart’s水肿胎儿的基因分析均无 Bam HI和 Bgl 酶解的特异性片段 ;7例β°地贫患儿出现典型临床表现 ,其基因突变类型为 CD17/ CD173例 ,CD17/ CD41- 42 2例 ,CD17/ IVSI- 11例。结论 :TAu- PAGE能可靠进行新生儿重型地贫的早期诊断 ,对于早期干预改善患儿预后和遗传咨询、评价地贫控制计划实施效果具有重要意义

 
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