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An evaluation of praziquantel on rabbit liver cirrhosis due to schistoso-miasis according to pathological changes was reported. Rabbits were treated 18 weeks after infection with praziquantel 100mg/kg/day for 2 days. All cured rabbits showed an excellent recovery 20-36 weeks after treatment with favorable pathological changes: i.e. ,(1)disappearance of vasodilatation, with decrease of hepatic arterioles and increase of portal branches; (2) disappearance of black-brown color, nodular appearance and hard feeling;... An evaluation of praziquantel on rabbit liver cirrhosis due to schistoso-miasis according to pathological changes was reported. Rabbits were treated 18 weeks after infection with praziquantel 100mg/kg/day for 2 days. All cured rabbits showed an excellent recovery 20-36 weeks after treatment with favorable pathological changes: i.e. ,(1)disappearance of vasodilatation, with decrease of hepatic arterioles and increase of portal branches; (2) disappearance of black-brown color, nodular appearance and hard feeling; and (3) disappearance of ova in portal areas, surrounded by collagen fibers and newly delevoped arterioles. Results indicated that praziquantel was a drug of choice in treatment for liver cirrhosis due to schistosomiasis.( Acknowledgmemt of support from the UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases ) 用肝脏血管造型和病理组织学方法观察吡喹酮对家兔日本血吸虫病肝硬化的影响。感染尾蚴后18周,用吡喹酮100mg/kg/日进行两天治疗,所有治愈家兔肝脏血管模型、病理形态及组织学的异常变化均在停药后20～36周得到很好恢复,提示吡喹酮是一个治愈血吸虫病肝硬化较为理想的药物。 SOD activity levels in the peripheral blood cells of 19 cases of early schistosomia- sis, 43 cases of late schistosomiasis, 9 cases of late schistosomiasis who have been essentially cored and 30 cases of healthy persons wfere determined.The results showed that SOD activity is 98 3U in patients with early schisto-miasis, 486U in patients of late schistosomiasis, 617U in patients of late schistosomiasis who have been essentially cured, and 1,411U in healthy persons, respectively.There exists a significant difference... SOD activity levels in the peripheral blood cells of 19 cases of early schistosomia- sis, 43 cases of late schistosomiasis, 9 cases of late schistosomiasis who have been essentially cored and 30 cases of healthy persons wfere determined.The results showed that SOD activity is 98 3U in patients with early schisto-miasis, 486U in patients of late schistosomiasis, 617U in patients of late schistosomiasis who have been essentially cured, and 1,411U in healthy persons, respectively.There exists a significant difference between the SOD activity in normal healthy persons and in patients of late schistosomiasis (P<0.001). 测定了各期血吸虫病患者与健康人的超氧化物歧化酶活力。结果;早期血吸虫病患者(19例)为983U/ml,晚期血吸虫病患者(43例)为486U/ml,晚期血吸虫病基本治愈者(9例)为617U/ml,健康人(30名)为1,411U/ml。统计处理表明健康人与晚期血吸虫病患者的酶活力有极显著差异(P<0.001),早期血吸虫病患者与晚期血吸虫病患者的酶活力也有极显著差异(P<0.001)。对超氧北物歧化酶在血吸虫病肝硬化发病机制中的作用进行了讨论。 A new composite pattern recognition method has been introduced to solve the problem by gathering and interpreting the clinical chemistry data relating to the two cirrhosises of liver in this paper. In order to obtain maximnm amount of information for discrimination, the necessary variables were selected by using the method of additional information test and the variables finally selected were then projected onto the optimal discrimination plane. The proposed method compared favorably to the Fisher desicion method... A new composite pattern recognition method has been introduced to solve the problem by gathering and interpreting the clinical chemistry data relating to the two cirrhosises of liver in this paper. In order to obtain maximnm amount of information for discrimination, the necessary variables were selected by using the method of additional information test and the variables finally selected were then projected onto the optimal discrimination plane. The proposed method compared favorably to the Fisher desicion method and Bayes stepwise desicion and a total consistence rate of 90.9％ could be reached. The results showed that pattern recognition approach was quite promising in solving clinical chemistry problems. 本文采用综合模式识别法,即将附加信息检验选变量的方法与最优判别平面投影结合起来,对血吸虫病肝硬化与门脉性肝硬化这两种临床上难以获正确诊断的疾患进行了计算机定量鉴别诊断研究。结果表明,该法优于Fisher和Bayes判别法,诊断正确率可达90.9％,展示了模式识别法应用于临床化学的广阔前景。
血吸虫病肝硬化
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There exists a significant difference between the SOD activity in normal healthy persons and in patients of late schistosomiasis (P<0.001). 统计处理表明健康人与晚期血吸虫病患者的酶活力有极显著差异(P<0.001),早期血吸虫病患者与晚期血吸虫病患者的酶活力也有极显著差异(P<0.001)。 对超氧北物歧化酶在血吸虫病肝硬化发病机制中的作用进行了讨论。 短句来源 Pattern Recognition as Applied to Clinical Chemistry 模式识别应用于临床化学——血吸虫病肝硬化与门脉性肝硬化的鉴别诊断研究 短句来源 To detect the telomerase and vascular endothelial growth factor (VEGF) activity in liver of mice with advance stage of schistosomiasis japonica and to discuss the relationship between periportal cirrhosis and hepatocarcinoma. 目的 检测晚期血吸虫病肝组织的端粒酶和血管内皮细胞生长因子 (VEGF)的活性 ,探讨日本血吸虫病肝硬化与恶性变的相关性。 短句来源 To study the prevalence of bacterial infection in schistosomiasis cirrhosis . 1119 cirrhotic patients associated with schistosomiasis (including 400 schistosomiasis cirrhotic patients with hepatocellular carcinoma) were retrospectively studied for bacterial infection. 为探讨血吸虫病肝硬化细菌感染的流行程度，我们回顾性地研究了1119例血吸虫病肝硬化患者（其中包括400例血吸虫病肝硬化肝癌患者）的各种细菌感染的发生率。 短句来源 Methods The experimental group included 10 rabbits infected percutaneously with cercariae of schistosomiasis japonica. The control group included 10 normal rabbits. The distribution of ET-1 and NOS in the lung was studied by immunohistochemistry staining. 方法 运用腹部敷贴法感染血吸虫尾蚴形成血吸虫病肝硬化门静脉高压症动物模型 ,模型组 (M组 ) 10只和正常对照组 (N组 ) 10只 ,应用免疫组织化学法对动物模型的肺组织中的ET -1、一氧化氮合酶 (nitricoxidesynthase ,NOS)进行定位性研究 ,并以正常兔作对照。 短句来源 更多 相似匹配句对
A STUDY OF ASCITES ASSOCIATED WITH LATE SCHISTOSOMIASIS AND CIRRHOSIS OF LIVER 晚期血吸虫病和肝硬化腹水分型的探讨 短句来源 Re-understanding of Liver Cirrhosis Induced by Schistosomiasis Japonica 对日本血吸虫病肝硬化的再认识 短句来源 PANCREATIC SCHISTOSOMIASIS 胰血吸虫病 短句来源 Cirrhotic myocardiopathy. 肝硬化心肌病 短句来源 LIVER RESECTION IN CIRRHOSIS OF LIVER 肝硬化病人的肝切除术 短句来源 
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