Conclusions: 1. Studies in vivo and in vitro demonstrated that when androgen-dependent parental LNCaP prostate cancer cells were maintained continuously in a regular RPMI1640 cell-culture medium, the biological behaviors of the LNCaP cells could be altered.
The orthotopic xenograft of human tumor in nude mice, with higher rate of successful grafting and tumor metastasis, was suggested to mimic more precisely human tumor in biologic behavior than subcutaneous model.
This indicates that there are different biological behaviors in tumors with different ploid pattern.
Protein bax and bcl-2 assay may be useful in understanding the biological behaviors of breast cancer.
Results: The significantly shortened doubling time, remarkably active proliferation ability in soft agar, and invasive growth in the abdomen of nude rat, demonstrated the malignant biological behaviors of KNRK cells.
After stable transfection into HepG2 cells, the biological behaviors of the survivin siRNA transfected HCC cells were observed.
The expression of DNA ploidy, the cell cycle and Ki67 antigen in nasopharyngeal carcinoma (NPC) were studied and their relationship with the clinical biological behaviors and prognosis of NPC was evaluated.
Relationship among COX-2 protein expression, PGs levels and biologic behavior in ovarian carcinoma tissues
Objective: To study the relationship among cyclooxygenase-2 (COX-2) protein expression, prostaglandins levels and biologic behavior in ovarian carcinoma tissues.
OBJECTIVE To explore the expression of the MDR1/P-glycoprotein, Fas and survivin and to examine their correlation with the biologic behavior of bladder transitional cell carcinoma (BTCC).
To date, more than 650 patients worldwide have been treated for gastric MALT lymphoma with antibiotics, and we have gained many new insights concerning the biologic behavior of this disease, especially from the deepened knowledge of cytogenetics.
The ability of imaging and cyst fluid analysis to predict the biologic behavior of the lesions has aroused much interest recently.
The results indicate that DI and reactivity of tumor cells to Ki-67 may reflect proliferative activity and be helpful for clinicians to judge the biological behaviour of tumors more accurately and objectively.
Carcinoembryonic antigen expression in gastric cancer as related to biological behaviour and prognosis
Cathepsin B expression and its relationship with microvessel density and biological behaviour of colorectal carcinoma
Purpose:The biological behaviour of prostate cancer is highly variable and prediction by the commonly employed prognostic parameters is not sufficient.
To compare the biological behaviour of sulphated insulin with that of a neutral highly purified monocomponent insulin, insulin receptor studies were performed on human and rat adipocytes and rat hepatocytes.