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(1) In 12 apparently healthy monkeys, the average respiratory rate was 46/minute, heart rate 227/minute, systolic/diastolic pressures 155/123 mm Hg, rectal temperature 39.0℃, erythrocytes 5.3 millionscu mm, leukocytes 15700 cu mm, among which lymphocytes 50.8%, neutrophils 45.0%, monocytes 2.0%, eosinophils 1.6%, and basophils 0.6%. (2) Sb-11 (H_2O_3Sb SCH_2COONa) is a pentavalent antimonial salt of stibonic acid. Intravenous injections at the daily dosage of 10 mg/kg in monkeys for 3 or 6 weeks produced no...

(1) In 12 apparently healthy monkeys, the average respiratory rate was 46/minute, heart rate 227/minute, systolic/diastolic pressures 155/123 mm Hg, rectal temperature 39.0℃, erythrocytes 5.3 millionscu mm, leukocytes 15700 cu mm, among which lymphocytes 50.8%, neutrophils 45.0%, monocytes 2.0%, eosinophils 1.6%, and basophils 0.6%. (2) Sb-11 (H_2O_3Sb SCH_2COONa) is a pentavalent antimonial salt of stibonic acid. Intravenous injections at the daily dosage of 10 mg/kg in monkeys for 3 or 6 weeks produced no cough, nausea, vomiting, anorexia or other reactions. Likewise, Sb-11 had no significant influence on the respiration, blood pressure, EXG, temperature, and the blood cell counts. (3) Five monkeys were each infected with 300 cercariae of Schistosoma japonicum. Beginning on the 43rd day after the infection, Sb-11 was given intravenously on 3 monkeys at the dosage of 10 mg/kg/day for 3 weeks. The remaining 2 monkeys served as control. After a holding period of another 4 weeks, the monkeys were autopsied. The numbers of the helminths remained in the 3 monkeys of the medicated group were 0, 1 and 13 respectively, with the schistosomes all degenerated, while those of the control group were 81 and 138 respectively. So the therapeutic effect of Sb-11 was vory remarkable. (4) The toxicity of Sb-11 was rather low. Drug tolerance to Sb-11 developed quickly in monkeys; which showed no toxic manifestations after a course as long as 6 weeks. Hence Sb-11 is recommended to be tried clinically on those patients who cannot receive intensive treatment of tartar emetic.

(一) 12只正常猴子平均呼吸頻率为46次/分,心跳为227次/分,收縮壓/舒張壓为155/12s毫米汞柱,體溫为39.0℃。平均紅血球5.3百萬/立方毫米,白血球15.7千/立方毫米,其中淋巴球50.8%,嗜中性45.0%,單核球2.0%,嗜酸性1.6%及嗜鹼性0.6%。 (二) Sb-11(H_2O_3Sb-SCH_2COONa)是5價之(月弟)酸鹽。猴子靜脈每天10毫克/千克,共3週或6週,無咳嗽、噁心嘔吐及食量減少等毒性反應,且對呼吸,血壓、心電圖、體溫及血球數等也無顯著影響。 (三) 5猴各感染日本血吸蟲尾蚴300條,其中2猴不给藥作對照,3猴自感染後第43天開始治療,劑量10毫克/千克/天,療程3週,停藥4週後解剖。對照2猴各餘存蟲81與138條;治療組8猴分別餘存蟲0,1與13條,蟲體萎縮,所以療效非常顯著。 (四) Sb-11毒性低,對猴子能產生耐藥性,療程延長至6週亦無毒性表現。所以我們建議,臨床上吐酒石短程療法禁忌的病人,可試用Sb-11。

The distribution and arrangement of the segmental bronchi and blood vessels of the lower lobe of right lung have been studied in fifty adult cadavers,by the same methods as those for the right upper and middle lobes reported previously. 1.Five segmental bronchi are constantly present in right lower lobe as described in textbook.Subapical bronchus (B~*) has been identified only 46% in this series of specimens. The prevailing pattern of the branches of the apical bronchus is a bifurcation of B~6c,B~6a+b. In 10%...

The distribution and arrangement of the segmental bronchi and blood vessels of the lower lobe of right lung have been studied in fifty adult cadavers,by the same methods as those for the right upper and middle lobes reported previously. 1.Five segmental bronchi are constantly present in right lower lobe as described in textbook.Subapical bronchus (B~*) has been identified only 46% in this series of specimens. The prevailing pattern of the branches of the apical bronchus is a bifurcation of B~6c,B~6a+b. In 10% of the medial basal segmental bronchus,its medial ramus (B~7b) is deep to the basal veins.Resection of this type of medial basal segment is considered to be harzardous. Posterior ramus of the lateral basal segmental bronchus (B~9c or BX~*9) has been found in 12% of the specimens.This has not been reported by E.A.Boyden or by other Chinese writers. 2.The number and pattern of origin of the segmental arteries of the right lower lobe are more complex than those of the segmental bronchi.Only in 14% of the speci- mens,the segmental arteries are the same in number and origin as the segmental bronchi, the rest being variable. Same as B~6,the prevailing pattern (58%) of the branches of the apical segmental artery is a bifurcation of A~6c,A~6a+b.In 48% of the specimens,the anterior basal segmental artery arises in a common stem with A~7 or A~7a.Comparing with other re- ports,this fact is significant. The total number of subapical segmental arteries (A~*) in this series of specimens is larger than its accompaning subapical segmental bronchi.Occasionally,the subapical artery arises from the beginning part of the posterior basal segmental artery. The number of the posterior ramus of the posterior basal segmental artery (A~(10)c or accessory subsuperior artery) is not always the same as its accompaning artery.It may arise from A~9 or the pars basalis of the right pulmonary artery. 3.The veins of the right lower lobe are same as the right upper and middle lobes, situated between segments or subsegments.They usually form two main veins which are drained into the right lower pulmonary vein.The basal veins may be classified into three types;the uncomplicated type is the prevailing pattern which occurs in 66%.

采用考查右肺上叶和中叶的方法考查了50例成年右肺下叶的支气管和血管。右下叶恒定的段支气管有五支,即尖段支气管(B~6),内侧基底段支气管(B~7),前基底段支气管(B~8),外侧基底段支气管(B~9),后基底段支气管(B~(10))。尖下段支气管(B~*)的出现率为46%。B~6最常见的分支型式是单干类二分支型(B~6c,B~6a+b),为84%。B~7的内侧支(B~7b)经右下肺静脉后方(深面)分布于椎旁面的为10%,在施行内侧基底段切除时应予注意,以免损伤右下肺静脉。外侧基底段支气管的后支(即BX~*a)在右下叶的出现率为12%。本文讨论了BX~*(10)和BX~*(9)的命名问题。右下叶动脉的分支数目和分支型式与支气管相同的仅为14%,彼此数目相同分支型式不同的为26%,其余动脉的分支数目和分支型式均不一致。尖段动脉(A~6)的常见分支型式与尖段支气管一样,是单干类的二分支型(A~6c,A~6a+b),为58%。前基底段动脉(A~8)与内侧基底段动脉(A~7)或内侧基底段动脉外侧支(A~7a)共干的占48%,与其它作者的结果之间有显著差别。尖下段动脉(A~*)的来源不一,它的总支数较B~*多,除A~*与...

采用考查右肺上叶和中叶的方法考查了50例成年右肺下叶的支气管和血管。右下叶恒定的段支气管有五支,即尖段支气管(B~6),内侧基底段支气管(B~7),前基底段支气管(B~8),外侧基底段支气管(B~9),后基底段支气管(B~(10))。尖下段支气管(B~*)的出现率为46%。B~6最常见的分支型式是单干类二分支型(B~6c,B~6a+b),为84%。B~7的内侧支(B~7b)经右下肺静脉后方(深面)分布于椎旁面的为10%,在施行内侧基底段切除时应予注意,以免损伤右下肺静脉。外侧基底段支气管的后支(即BX~*a)在右下叶的出现率为12%。本文讨论了BX~*(10)和BX~*(9)的命名问题。右下叶动脉的分支数目和分支型式与支气管相同的仅为14%,彼此数目相同分支型式不同的为26%,其余动脉的分支数目和分支型式均不一致。尖段动脉(A~6)的常见分支型式与尖段支气管一样,是单干类的二分支型(A~6c,A~6a+b),为58%。前基底段动脉(A~8)与内侧基底段动脉(A~7)或内侧基底段动脉外侧支(A~7a)共干的占48%,与其它作者的结果之间有显著差别。尖下段动脉(A~*)的来源不一,它的总支数较B~*多,除A~*与同数的B~*伴行外,还有三支A~*伴两支B~*的现象。后基底段动脉后支(A~(10)c)(即AX~*(10))的起源和支数与尖下段动脉有相似的现象。尖下段动脉和后基底段动脉的后支与它们所伴行的支气管之间,在起源上和分支数目上存在着异源异数或异源同数或同源异数的关系。右肺下叶的静脉与右上叶和中叶一样,行于段间或亚段间,汇集成尖段静脉、上基底静脉和下基底静脉三大支。上、下基底静脉先汇集成总基底静脉,再与尖段静脉成右下肺静脉。上基底静脉和下基底静脉的成型式,本文分为正常型、分裂型和异常型。正常型是常见的型式,为66%。右肺下叶的静脉与支气管和动脉间缺少联系。动脉与支气管在分支型式上不尽相同,但在分布上却紧密伴随。

The pattern of branching and distribution of the blood vessels in the right lower

1.解剖了50个成人的右肺下叶,详细观察了右下叶血管的分支情况。 2.上段动脉(A~6)的发起、分支类型都进行了观察。A~6是一支型者68%,其中二分支者50%,三分支者18%;二支型者30%;三支型者2%。 3.在19例有B~*(22支)的标本上,有A~*27支。1例可有A~*1—3支,但以1支者较多(13例)。在43例有BX_(10)~*(57支)的标本上,有AX_(10)~*59支。 4.A~7是一支型者78%,其中34%的A~7单独起于肺底段动脉,其余的与其他动脉合干。A~7是二支型者22%。根据A~7与肺底段静脉的关系又可分成四型,Ⅰ、Ⅱ型占68%,Ⅲ型占10%,Ⅳ型占22%。A~8的普通型只有22%,与其他动脉合干者44%,分二支发起者34%,故A~8的变异远比B~8为多。A~9的普通型只有44%,而B~9的普通型有82%,故A~9的变异亦比B~9多。A~9分二支发起者38%,与其他动脉合干者16%。A~(10)包括有A_a~(10)与A_b~(10)两个分支者有98%,其中有5例,自A~(10)或A_b~(10)发出A~*、A_b~7或A_b~9。 5.上段的静脉汇合成一支V~6者82%,二支V...

1.解剖了50个成人的右肺下叶,详细观察了右下叶血管的分支情况。 2.上段动脉(A~6)的发起、分支类型都进行了观察。A~6是一支型者68%,其中二分支者50%,三分支者18%;二支型者30%;三支型者2%。 3.在19例有B~*(22支)的标本上,有A~*27支。1例可有A~*1—3支,但以1支者较多(13例)。在43例有BX_(10)~*(57支)的标本上,有AX_(10)~*59支。 4.A~7是一支型者78%,其中34%的A~7单独起于肺底段动脉,其余的与其他动脉合干。A~7是二支型者22%。根据A~7与肺底段静脉的关系又可分成四型,Ⅰ、Ⅱ型占68%,Ⅲ型占10%,Ⅳ型占22%。A~8的普通型只有22%,与其他动脉合干者44%,分二支发起者34%,故A~8的变异远比B~8为多。A~9的普通型只有44%,而B~9的普通型有82%,故A~9的变异亦比B~9多。A~9分二支发起者38%,与其他动脉合干者16%。A~(10)包括有A_a~(10)与A_b~(10)两个分支者有98%,其中有5例,自A~(10)或A_b~(10)发出A~*、A_b~7或A_b~9。 5.上段的静脉汇合成一支V~6者82%,二支V~6者18%。V~8、V~9与V~(10)汇成上下肺底段静脉。上下肺底段静脉的成型式分正常型(52%)、异常型(12%)与分裂型(36%),其中以V~8与V~9汇成上肺底段静脉,V~(10)移行成下肺底段静脉的正常型最多,占34%。上下肺底段静脉汇成肺底段静脉者有90%。右下叶静脉由肺底段静脉与一支型V~6汇成者有70%。

 
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