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67 out of 124 Chinese technical workers, who returned from Africa where Schistosomiasis rnansoni was endemic, were found to be infected with this parasite on stool examination ( including ova examination and hatching test ) . Several other diagnostic procedures including intradermal test ( ID ), circumoval precipitin test ( COP ) and cercarienhullen reaction (CHR) were also employed at the same time for the 67 proved cases, and their positive rates were found to be 41.7%, 80.6-94.0% (48 or 72 hours' incubation...

67 out of 124 Chinese technical workers, who returned from Africa where Schistosomiasis rnansoni was endemic, were found to be infected with this parasite on stool examination ( including ova examination and hatching test ) . Several other diagnostic procedures including intradermal test ( ID ), circumoval precipitin test ( COP ) and cercarienhullen reaction (CHR) were also employed at the same time for the 67 proved cases, and their positive rates were found to be 41.7%, 80.6-94.0% (48 or 72 hours' incubation ) and 97.2% respectively. The antigens used for all these tests were prepared from either adult parasites, ova or cercariae of Schistosoma japonicum. It was found that there was a high degree of cross reaction between S. japonicum ( antigens ) and S. mansoni infections. As a preliminary screening test, CHR appears to be more sensitive than COP.Follow-up study showed that 10-15 months after one or two courses of specific treatment, COP and CHR were still found to be positive for 13(21%) and 48 ( 79% ) cases respectively, whereas stool examinations in all these cases showed negative results. It seems that COP may be a more useful tool in assessing the therapeutic efficacy of specific treatment for this disease.

本文用日本血吸虫成虫及虫卵抗原皮内试验、冻干虫卵环卵反应、尾蚴膜反应和粪便检查等方法调查124名援外人员,阳性率分别为25.9%、55.6%、57.2%和54.0%,属曼氏血吸虫感染。粪检阳性的尾蚴膜和环卵反应阳性率分别达97.0%和94.0%。治疗后复查表明,环卵反应转阴率较尾蚴膜反应为高。作者还讨论了用日本血吸虫各期抗原检查曼氏血吸虫病病人及考核疗效的价值。

The active rosette test was adapted as in vitro assay and researched for relation withhuman tumor antigens——gastric cancerous, lung cancerous and hepatic cancerous. Peripheral lymphocytes were purified from 114 cancer patients, 48 noncancer patients and 30 normal adults. Tumor antigen, incubated with lymphocytes from a corresponding cancer patient, produced a significant increase in the ability of the lymphocytes to form active rosette-forming cells (A-RFG) when compared with lymphocytes cultured without antigen...

The active rosette test was adapted as in vitro assay and researched for relation withhuman tumor antigens——gastric cancerous, lung cancerous and hepatic cancerous. Peripheral lymphocytes were purified from 114 cancer patients, 48 noncancer patients and 30 normal adults. Tumor antigen, incubated with lymphocytes from a corresponding cancer patient, produced a significant increase in the ability of the lymphocytes to form active rosette-forming cells (A-RFG) when compared with lymphocytes cultured without antigen (p∠0.001). This increasing effect on A-RFC still remained after refrigeration. Tumor antigen incubated with lymphocytes from normal donors produced no increase in their A-RFG. It should be noted that this assay appears in a certain manner to be specific for the antigen to which the individual is corresponding cancer patient, for example, gastric cancerous antigen activated A-RFG of a gastric cancerous patient, but produced no increase in breast patient. This assay provides a new in vitro method for investigating mechanism for cell-mediated immunity and also a new specific diagnostic method for cancer.

在试管内研究人类肿瘤抗原-胃癌、肺癌和肝癌抗原——与活性玫瑰花形成试验的关系。由114例肿瘤病。48例非肿瘤病人和30例正常人的血液标本中分离淋巴细胞。肿瘤抗原与相应的癌患者的淋巴细胞温育后,淋巴细胞形成活性玫瑰花的百分率比未加抗原的对照显著增加(P<0.001)。与抗原温育过的淋巴细胞经冷藏后仍保留这种激活效应。肿瘤抗原与正常人的淋巴细胞温育过不产生活性玫瑰花细胞的增多效应。值得注意的是,这种测定具有一定特异性,例如胃癌抗原能激活胃癌病人的活性玫瑰花细胞而对乳癌病人无激活效应。这一实验可做为研究细胞免疫机制的新的体外试验方法,并为肿瘤的特异性诊断提供新的方法。

X-ray features of 8 cases of early gastric cancer discovered in our clinical work were briefly described. One of them showed a small filling defect at the greater curvature of prepyloric region. 5 cases were mainly ulcerative in appearance. One case with no remarkable abnormality in preoperative x-ray examination but biopsy verified chronic gastritis with carcinomatous change. Retrospective review of the x-ray films discovered that the lesser curvature of prepyloric region was flattened and slightly blurred....

X-ray features of 8 cases of early gastric cancer discovered in our clinical work were briefly described. One of them showed a small filling defect at the greater curvature of prepyloric region. 5 cases were mainly ulcerative in appearance. One case with no remarkable abnormality in preoperative x-ray examination but biopsy verified chronic gastritis with carcinomatous change. Retrospective review of the x-ray films discovered that the lesser curvature of prepyloric region was flattened and slightly blurred. In the last case there were three gas bubble like filling defects at the cardiac region which verified later as an early adenocarcinoma.According to our retrospective study, we considered that early gastric cancers can be discovered by barium meal examination. The key point is how to discover the lesion as early as possible. The technigue of double contrast method used in our department was introduced.

本文简要地叙述了我院临床诊断中发现并经病理证实的8例早期胃癌的X线所见。其中1例表现为胃窦幽门前区大弯侧充盈缺损;5例以溃疡病变为主;1例术前X线检查未发现异常,活检证实胃窦小弯侧慢性胃窦炎伴有腺体不典型增生及癌变,后再复习其X线片发现胃窦小弯侧较平,轮廓毛糙,1例X线检查发现胃底贲门部有小气泡样充盈缺损,手术证实为腺癌。 通过本病例复习,我们认为早期胃癌只要在粘膜上有一定的直观所见,在X线胃肠造影中是能够显示出来而且也可以被认识的,但关键在于早期发现,为此简单地介绍了我院采用的口服发泡剂双重造影方法及操作技术。

 
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