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Under the guidance of Chairman Mao's revolutionary line, the medical workers of our hospital have gone out to the factories, worker-shops and workers' residential districts to examine and prevent diseases of the broad labouring masses. The variation of serum lipids in 1835 healthy subjects (from the newborn to 102 years of age), most of them workers, were investigated during the period from October, 1973 to December, 1974. The results are summarized as follows:The frequency distribution of serum cholesterol...

Under the guidance of Chairman Mao's revolutionary line, the medical workers of our hospital have gone out to the factories, worker-shops and workers' residential districts to examine and prevent diseases of the broad labouring masses. The variation of serum lipids in 1835 healthy subjects (from the newborn to 102 years of age), most of them workers, were investigated during the period from October, 1973 to December, 1974. The results are summarized as follows:The frequency distribution of serum cholesterol values followed the normal distribution in all age groups. The frequency distribution of values for serum triglyceride and β-lipoprotein were both skewed in most age groups.In general, there was a tendency for the concentration of serum lipids to increase with age. There was no difference in cholesterol concentration between men and women below fifty years of age, while women had a higher value than men at ages above fifty. The serum triglyceride level was slightly higher in men than in women below fifty; above fifty years of age women had a significantly higher serum triglyceride level than men.The results of statistical analysis indicate that the normal limits of values for serum cholesterol, triglyceride and β-lipoprotein in healthy working people to be 100 mg/100 ml, 110 mg/100 ml and 500 mg/100 ml respectively; the upper limits being 220 mg/100 ml, 160 mg/100 ml and 610 mg/100 ml respectively. Using the WHO classification, Type Ⅱ_a, Type Ⅱ_b and Type Ⅳ hyperlipoproteinemia were shown to be the most prevalent types in this population.The concentration of β-lipoprotein closely correlated with those of cholesterol and triglyceride. It was shown that the quantitative determination of β-lipoprotein is a simple and effective method for screening hyperlipidemia.This preliminary investigation indicated that the pattern of serum lipid variations of the working people in our country was different from that of western countries. Differences in race, the social system, and dietary habits, probably all account for such differences in pattern.

在毛主席革命路线的指引下,我院医务工作者走出医院大门,深入工厂车间,街道里弄,为劳动人民查病、防病。本文报告我院自1973年10月至1974年12月调查1385名以工人为主的上海市健康人(自新生儿到102岁老年人)的血脂改变,所得结论如下: 1.血脂含量的频率分布:各年龄胆固醇含量基本上呈正态分布,甘油三酯和β脂蛋白含量多数年龄均呈偏态分布。2.血脂含量与年龄和性别的关系:一般均有随年龄而增高的趋势。胆固醇在50岁以前男女并无差别,50岁以后女性高于男性。甘油三酯50岁以前男性略高于女性,50岁以后女性显著增高超过男性。3.根据统计分析,求得健康劳动人民血胆固醇、甘油三酯和β脂蛋白的正常上限分别为180毫克/100毫升、110毫克/100毫升和500毫克/100毫升;过高界限分别为220毫克/100毫升、160毫克/100毫升和610毫克/100毫升。按国际暂行的分类标准,本中出现的高脂蛋白血症以II_a、II_b和IV型最为多见。4.β脂蛋白含量与胆固醇和甘油三酯含量之间存在着密切关系。认为β脂蛋白测定是一项预测高脂血症的简便有效的方法。初步调查表明,我国人民血脂改...

在毛主席革命路线的指引下,我院医务工作者走出医院大门,深入工厂车间,街道里弄,为劳动人民查病、防病。本文报告我院自1973年10月至1974年12月调查1385名以工人为主的上海市健康人(自新生儿到102岁老年人)的血脂改变,所得结论如下: 1.血脂含量的频率分布:各年龄胆固醇含量基本上呈正态分布,甘油三酯和β脂蛋白含量多数年龄均呈偏态分布。2.血脂含量与年龄和性别的关系:一般均有随年龄而增高的趋势。胆固醇在50岁以前男女并无差别,50岁以后女性高于男性。甘油三酯50岁以前男性略高于女性,50岁以后女性显著增高超过男性。3.根据统计分析,求得健康劳动人民血胆固醇、甘油三酯和β脂蛋白的正常上限分别为180毫克/100毫升、110毫克/100毫升和500毫克/100毫升;过高界限分别为220毫克/100毫升、160毫克/100毫升和610毫克/100毫升。按国际暂行的分类标准,本中出现的高脂蛋白血症以II_a、II_b和IV型最为多见。4.β脂蛋白含量与胆固醇和甘油三酯含量之间存在着密切关系。认为β脂蛋白测定是一项预测高脂血症的简便有效的方法。初步调查表明,我国人民血脂改变规律与西方资本主义国家不尽一样,可能与社会制度、民族特点、饮食习惯不同有关。

Der duroh Fuetterung mit exogenem Cholesterin beim normalen Meerschweinchen hervorgerufene Hyperlipidaemie konnte durch grosse Vitamin C Dosis deutlich verbessert, wenn man das Vitamin C gleichzeitig mit exogenem Cholesterin dem Meerschweinchen zufuerhte. Mit Verbesserung der Hyperlipidaemie wurde das Verhaeltnis von Cholesterin/Phosphatid im Serum auch normal hergestellt. Ferner, die durch Fuetterung mit exogenem Cholesterin verursachte Anhaeufung von Cholesterin in Leber hat man bei gleichzeitiger Zufuhr von...

Der duroh Fuetterung mit exogenem Cholesterin beim normalen Meerschweinchen hervorgerufene Hyperlipidaemie konnte durch grosse Vitamin C Dosis deutlich verbessert, wenn man das Vitamin C gleichzeitig mit exogenem Cholesterin dem Meerschweinchen zufuerhte. Mit Verbesserung der Hyperlipidaemie wurde das Verhaeltnis von Cholesterin/Phosphatid im Serum auch normal hergestellt. Ferner, die durch Fuetterung mit exogenem Cholesterin verursachte Anhaeufung von Cholesterin in Leber hat man bei gleichzeitiger Zufuhr von Vitamin C bloss die Haelfte davon gefunden; ausserdem wurde die Ablagerung von Triglyceriden in der Leber und von Cholesterin in der Aortenwand nicht mehr significant vermehrt als die Kontroll-Werte. Weiter, die Belastung mit exogenem Cholesterin beim Meerschweinchen scheint besonders den Vitamin C-Verbrauch in Leber zu steigern. Zum Schluss wurde die moegliche Mechanismus des C-Vitamins auf den Cholesterinstoffwechsel kurz diskutiert.

给正常豚鼠喂饲大量胆固醇所引起的高脂类血症,可因同时给予大量维生素C而得到明显减轻,使血中胆固醇与磷脂的比值恢复正常,明显降低肝内胆固醇及甘油三酯的蓄积,并使主动脉壁内胆固醇的沉积与正常对照无明显差异。另外本实验中还观察到给豚鼠大量胆固醇能使肝内维生素C的含量明显减少,从而说明维生素C与胆固醇代谢有密切关系。最后本文关于维生素C对胆固醇代谢作用机制进行了简短的讨论。

The ultrasonic cardiographic investigation was performed in 5 groups of normal youths, working with various labour load at different altitudes, i.e., 4,500 m. 2,800 m. and 80 m.above sea level. The results showed that the work of right heart was increased with labour intensity and height above sea level, and was reflected by an increase in transverse diameters of the right ventricle, the right ventricular outflow tract and the right pulmonary artery, a delay of the isometric diastolic interval of right ventricle,...

The ultrasonic cardiographic investigation was performed in 5 groups of normal youths, working with various labour load at different altitudes, i.e., 4,500 m. 2,800 m. and 80 m.above sea level. The results showed that the work of right heart was increased with labour intensity and height above sea level, and was reflected by an increase in transverse diameters of the right ventricle, the right ventricular outflow tract and the right pulmonary artery, a delay of the isometric diastolic interval of right ventricle, and a rise in incidence of pulmonary hypertension at high altitude, especially in groups with heavy physical load. On the other hand, adaptation of left heart to high altitude was rather good, because there was no statistic difference in stroke volume, minute volume, cardiac index and ejection fraction between groups at high altitude and at sea level, in spite of an obvious decrease in transverse diameter and end-diastolic volume of left ventricle at an altitude of 4,500 m.

对在不同海拔高度(4500~4600米,2800米、80米)从事不同强度劳动的五正常男性青年作了超声心动图检查。结果表明,右心负荷随劳动强度和海拔高度的增加而加重,表现在高原右室横径,右室流出道与右肺动脉内径增宽,右室等容舒张期明显延长,肺动脉高压发生率明显增加,重劳动尤为突出。左心对高原环境的适应则较好。在海拔4500~4600米高原左室横径及舒张末期容积虽然明显缩小,但每搏与每分心输出量,心排血指数与排血分数等与平原对照值却没有显著差异。

 
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