Pumping by a 809 nm laser diode, the thermal tip generates a maximum temperature of 465° in air (with pumping power of 1124 mW) and 98° in egg white (with pumping power of 933 mW), which is high enough for laser thermotherapy.
Basing on the view of energy,the interaction of lasers with biological tissue and the process of developing laser heat source are discussed. The mico-mechanism of laser heat therapy are also studied. We go further into tissue temperature varying with laser and tissue parameter in laser irradiating,quantitatively,and put forward the theoretical basis of selecting treatment parameter in laser thermotherapy.
During laser-induced interstitial thermotherapy,the laser-tissue interaction includes two aspects:one is photon migration,the other is bioheat transfer. The distribution of photons and energy in tissue can be calculated with Monte-Carlo simulation based on transfer theory.
Methods: Tumor - bearing mice were divided into control group and hyperthermia group. Tumor - bearing mice of hyperthermia group were given Nd: YAG luser radiation and the temperature in tumor edge was controled at 43℃ (about 424mW/cm2) for 30 minutes.
Results: The experments showed the average tumor weight of hyperthermia group had significant differecces compared with that of control group (P < 0.01). The trmor inhibitory rates of hyperthermia group was 31. 8%. The DNA content showed very significant decrease after Nd: YAG laser radiation (P < 0.01).
A sapphire probe and a bare fibre were compared with respect to temperature control and distribution and light fluence in interstitial laser thermotherapy.
This paper presents the thermal treatment by laser beam, electron beam and hot isostatic pressing (HIP) process and the mechanical treatment by shot peening.
Laser-induced interstitial thermotherapy (LITT) performed under MRI guidance results in precise and reproducible areas of induced necrosis with a local control of 94 %, and with an improved survival rate.
The aim of the study was to evaluate the feasibility, safety and effectiveness of CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy (LITT) in adrenal metastases.
Objective: To study the dose select and the inhibiting effect of hyperthermia induced by Nd:YAG laser on the transplanted sarcoma 180 in mice. Methods: Tumor - bearing mice were divided into control group and hyperthermia group. Tumor - bearing mice of hyperthermia group were given Nd: YAG luser radiation and the temperature in tumor edge was controled at 43℃ (about 424mW/cm2) for 30 minutes. The DNA contant of tumor cell were also measured with microspectrophotometry 24 hours after laser radiation.The tumo...
The effects of hyperthermia induced by Nd:YAG laser on sarcoma 180 in mice were studied. The DNA content of tumor cells was also measured with microspectrophotometry after the treatment. The tumor bearing mice were divided into the control group and the hyperthermia group. Tumor bearing mice of hyperthermia group were given Nd:YAG laser radiation and the temperature in tumor edge was controlled at 43℃ (about 424mW/cm 2) for 30 minutes. The result showed that the average tumor weight of hyperthermia g...
During laser-induced interstitial thermotherapy,the laser-tissue interaction includes two aspects:one is photon migration,the other is bioheat transfer.The distribution of photons and energy in tissue can be calculated with Monte-Carlo simulation based on transfer theory.With Pennes equation and Weinbaum & Jiji model,temperature distribution and changes in tissue could be described.It is very important to unite the both models.Dynamical process of coagulation is monitored through changes of the tissue's sca...