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   阿米替林 在 精神病学 分类中 的翻译结果: 查询用时:0.016秒
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阿米替林
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  amitriptyline
This method provides not only the detection of trace substances (for example, opiates and amitriptyline at a picogram level) but also their identification based on the most probable evaporation temperature.
      
We report about 5 patients (3 male, 2 female, age 19 to 73), who were treated with hemoperfusion therapy because of acute amitriptyline intoxication with severe cardiotoxic side effects.
      
We compared these data with those of 4 patients who were treated without hemoperfusion after amitriptyline intoxication.
      
Initially, amitriptyline plasma levels in this group were 1872±1088ng/ml and fell to 877±367ng/ml after hemoperfusion.
      
In comparison, in the patients not treated with hemoperfusion, amitriptyline plasma levels were 1628±1273ng/ml at admission, decreasing to 746±455ng/ml spontaneously the following day.
      
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From December 1983 to February 1985, 37 OPD patients, suffered from obssession, received medical therapy under observation. Among them 28 cases took chlorimipramine, 4-wk trial with daily dose 20-80mg, while the rest amitriptyline as control.Cure and improvement were found to be 76%in the former while 55% in the latter. These figures

37例强迫症患者用氯丙咪嗪治疗,按疗效作了随机对照研究。氯丙咪嗪剂量为20-80mg/d,疗程为1mo(月)。结果:有效率76%,对照组用阿米替林有效率为56%。两者在统计学上无明显差异。本文结果提示,氯米咪嗪与阿米替林相比,在治疗强迫症方面疗效无差异。然而,对顽固的强迫行为疗效均欠佳。在强迫症无更有效的药物治疗前,氯丙咪嗪仍是可供选择的药物。

Alprazolam, 8-chloro -1-me-thyl-6-phenyl-4H-s-triazolo [4,3-α] [1, 4] benzodiazepine, was used on 142 patients (55M, 87F, aged 37±SD13 yr)with mental disorders (depression, neurasthenia, anxiety disorders, hysteria, schizo-Phrenia, obsessive-compulsive disorder, etc). The daily oral dose was increased from 0.8-1.2 mg to the maximum (2± SD 0.6 mg)in about lwk,and then maintained for 4 wk. The overall effective rate was 91%, with 51% of marked improvement. The adverse drug reactions included somnolence, dizziness,...

Alprazolam, 8-chloro -1-me-thyl-6-phenyl-4H-s-triazolo [4,3-α] [1, 4] benzodiazepine, was used on 142 patients (55M, 87F, aged 37±SD13 yr)with mental disorders (depression, neurasthenia, anxiety disorders, hysteria, schizo-Phrenia, obsessive-compulsive disorder, etc). The daily oral dose was increased from 0.8-1.2 mg to the maximum (2± SD 0.6 mg)in about lwk,and then maintained for 4 wk. The overall effective rate was 91%, with 51% of marked improvement. The adverse drug reactions included somnolence, dizziness, agrypnia, etc. Ami- triptyline was used on 40 patients (15M, 25F, aged 39±12 yr) as control.The initial dose was 50-100 mg/d.Then the dose was increased to maximum (198 ± SD12.5 mg) in 2wk or so and maintained for 4 wk. No marked difference was found between alprazolam and amitriptyline ia therapeutic effects.

阿普唑仑为新型苯氮类药物,其化学名为8-氯-1-甲基-6-苯基-4H-1,2,4-三唑[4,3-α][1,4]苯并氮(艹卓)。用该药治疗142例(男55,女87,平均年龄37±SD13岁)精神疾病(抑郁症、神经衰弱、 焦虑症、癔症、精神分裂症及强迫行为等)日剂量 自0.8-1.2mg开始,1wk内增至最高量(2±0.58mg),治疗4wk,总有效率达91%,其中显效率为50.7%。主要副反应为嗜睡、头晕及失眠等。 对照组40例(男15,女25,平均年龄39±SD12岁)用阿米替林治疗,日剂量自50-100mg开始2wk左右增至最高用量(198±12.5mg)治疗4wk。2组疗效无显著差异。

A special slow-releasing pharmaceutical preparation of amitriptyline (Saroten Zetard) had its therapeutic efficiency evaluated against a star dard preparation in 30 mental depressive patients. Conducted with random and double-blind method,there were no significant differences between these two through a course of treatment of a 4-wk duration.

本文对30例抑郁症病人应用阿米替林胶囊缓释剂和阿米替林片剂进行双盲法疗效比较,其结果2组的临床疗效和副反应均无明显差异。

 
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