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弯曲断裂载荷
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  “弯曲断裂载荷”译为未确定词的双语例句
     Methods T-SOD activity,MDA level in serum,E-2 and T levels in plasma,binding capacity of M receptor,bone density of proximal,middle and distal segments of left femur,and break bending load of right femur were determined in the rats aged 6,24,and 30 months.
     方法测定不同月龄SD雄性大鼠血清T-SOD活性及MDA含量、血浆E2及T的含量、脑组织M受体结合容量以及左侧股骨近段、中段、远段的骨密度和右侧股骨的弯曲断裂载荷
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     The binding capacity of M receptor,and the femur bone density in respective segments and the femur break bending load of the rats aged 30 months were significantly lower than those of the rats aged 24 months(P<0.05).
     30月龄雄性大鼠脑组织M受体结合容量和股骨各段骨密度及弯曲断裂载荷明显低于24月龄雄性大鼠(P<0.05)。
短句来源
     Effects of Sr 2+ on body weight, body length, AKP activity of serum, calcium content of urine and breaking load of bended femur for rats were not found.
     尚未发现锶对动物体重、体长、血清AKP活性、尿钙水平以及股骨弯曲断裂载荷的影响。
短句来源
     Bone indexes (bone density of the proximal, middle and distal segments of left femur and break bending load of right femur) and brain indexes (binding capacity of M receptor and cholinesterase activity of brain) were measured after responding treatment.
     各组相应处理以后分别测定各组大鼠的骨参数 (左侧股骨近段、中段、远段的骨密度和右侧股骨的弯曲断裂载荷 )以及脑参数 (脑组织M受体结合容量和胆碱酯酶活性 )。
短句来源
     Results: In bone, BSYJR could not only increase the bone mineral density in various segments of femur, but also raise the bending break load of femur dose effect dependently.
     结果 :在骨方面 ,补肾益精方既能量效依赖性地增加大鼠股骨各段骨密度 ,又能量效依赖性地提高大鼠股骨弯曲断裂载荷 ;
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Effects of strontium at a high level in drinking water on growth and development of rat bone were studied. The results showed that Sr 2+ concentration from 5 to 500mg/L in drinking water could increase the contents of strontium in blood serum, urine, femur, mixilla and tooth in Wistar rats exposed to Sr 2+ for 12 weeks with an obvious dose response relationship. In addition, strontium at over 50mg/L could decrease the contents of calcium in bone, increase the contents of calcium in tooth and bone...

Effects of strontium at a high level in drinking water on growth and development of rat bone were studied. The results showed that Sr 2+ concentration from 5 to 500mg/L in drinking water could increase the contents of strontium in blood serum, urine, femur, mixilla and tooth in Wistar rats exposed to Sr 2+ for 12 weeks with an obvious dose response relationship. In addition, strontium at over 50mg/L could decrease the contents of calcium in bone, increase the contents of calcium in tooth and bone density, and decrease the levels of calcium in blood serum except female rats at the 12th week. Effects of Sr 2+ on body weight, body length, AKP activity of serum, calcium content of urine and breaking load of bended femur for rats were not found. However, there are differences in the effects of strontium on growth and development of bone between male and female rats. At the 12th week the content of calcium in blood serum decreased in male rats but increased in female rats in exposed groups. At the 4th and 8th weeks, urine Hop/Cr in male rats increased but it remained normal level in female rats. Sr 2+ increased the bone density of mixilla in male rats but it did not increase that of femur in female rats .It is suggested that such changes may be a result of the differences in endocritic regulation and metabolic process between two sexes.

研究了高锶饮水对大鼠骨骼生长发育的影响。结果表明,饮水中锶浓度为5~500mg/L达12周可引起Wistar大鼠血清、尿、股骨、颌骨和牙齿中锶含量增高,呈明显的剂量-反应关系。同时,锶还可使骨骼钙含量降低,牙齿钙含量和骨骼的骨密度增高,以及除第12周雌性大鼠外血清钙水平下降。尚未发现锶对动物体重、体长、血清AKP活性、尿钙水平以及股骨弯曲断裂载荷的影响。然而,锶对动物骨骼生长发育影响性别之间存在差异,如在第12周染锶组雄性大鼠血清钙含量降低,而雌性大鼠升高;在第4周和第8周时,仅雄性大鼠尿Hop/Cr比值增高,而雌性大鼠维持于正常水平;Sr2+还使雄性大鼠颌骨骨密度增加,而雌性大鼠股骨骨密度增加。上述改变提示可能是动物性别之间在内分泌调节和代谢过程上不同的结果。

Objective: To evaluate the effect of Bushen Yijing recipe (BSYJR) in delaying senility of bone and brain of aged male rats and infer its mechanism in delaying systemic senility. Methods: Forty male SD rats, 24 months old were randomly divided into 4 groups, the baseline control group, the aged control group (30 months old), the BSYJR high dose group and the BSYJR low dose group. The latter two groups received BSYJR treatment from 24 months old to 30 months old. Bone indexes (bone density of the proximal, middle...

Objective: To evaluate the effect of Bushen Yijing recipe (BSYJR) in delaying senility of bone and brain of aged male rats and infer its mechanism in delaying systemic senility. Methods: Forty male SD rats, 24 months old were randomly divided into 4 groups, the baseline control group, the aged control group (30 months old), the BSYJR high dose group and the BSYJR low dose group. The latter two groups received BSYJR treatment from 24 months old to 30 months old. Bone indexes (bone density of the proximal, middle and distal segments of left femur and break bending load of right femur) and brain indexes (binding capacity of M receptor and cholinesterase activity of brain) were measured after responding treatment. Results: In bone, BSYJR could not only increase the bone mineral density in various segments of femur, but also raise the bending break load of femur dose effect dependently. In brain, BSYJR could both up regulate the binding capacity of M receptor and inhibit the activity of cholinesterase. Conclusion: BSYJR could delay the senility of bone and brain in male rats, inferring that it might regulate integrally the abnormality of aging in Kidney Asthenia and Essence Deficiency through mediation of nerve endocrine immunity network.

目的 :评价补肾益精方延缓老年雄性大鼠骨衰老与脑衰老的作用 ,探讨此方延缓整个机体衰老的机制。方法 :4 0只 2 4月龄SD雄性大鼠随机分为 2 4月龄本底对照组、30月龄增龄对照组、补肾益精方低剂量组、补肾益精方高剂量组 ,每组各 10只。低剂量组、高剂量组均自 2 4月龄给药至 30月龄。各组相应处理以后分别测定各组大鼠的骨参数 (左侧股骨近段、中段、远段的骨密度和右侧股骨的弯曲断裂载荷 )以及脑参数 (脑组织M受体结合容量和胆碱酯酶活性 )。结果 :在骨方面 ,补肾益精方既能量效依赖性地增加大鼠股骨各段骨密度 ,又能量效依赖性地提高大鼠股骨弯曲断裂载荷 ;在脑方面 ,补肾益精方不仅能上调大鼠脑组织M受体结合容量 ,而且又能抑制大鼠脑组织胆碱酯酶活性。结论 :补肾益精方具有同时延缓雄性大鼠骨衰老与脑衰老的作用 ;推测该方似通过神经内分泌免疫网络的介导从整体角度调整衰老机体肾虚精亏之异常。

Objective To investigate the effect of a kind of tissue engineered bone implants on healing of segmental bone defects. Methods A 15 mm bone defect experimental model at the right radius of New Zealand white rabbit was made. 24 animals of this model were divided into three groups at random. PLGA scaffords loaded with 5 mg BMP and about 1×106 BMSCs were implanted in Group 1(n=10); PLGA scaffords loaded with 2.5 mg BMP and about 1×106 BMSCs were implanted in Group 2(n=7); PLGA scaffords loaded with 1 mg BMP and...

Objective To investigate the effect of a kind of tissue engineered bone implants on healing of segmental bone defects. Methods A 15 mm bone defect experimental model at the right radius of New Zealand white rabbit was made. 24 animals of this model were divided into three groups at random. PLGA scaffords loaded with 5 mg BMP and about 1×106 BMSCs were implanted in Group 1(n=10); PLGA scaffords loaded with 2.5 mg BMP and about 1×106 BMSCs were implanted in Group 2(n=7); PLGA scaffords loaded with 1 mg BMP and about 1×106 BMSCs were implanted in Group 3(n=7). The osteogenesis at the defect area was observed by regular roentgenography and X-ray analysis, histological changes at the bone defects at 4th, 8th, 12th weeks after operation were studied and the new bone formation was measured by image analysis. Biomechanical analysis was done 12 weeks after operation. Results A large quantity of callus was found in all the 3 groups 4 weeks after repair. At the 12th week, the complete bone healing rate was 7/8, 3/5, 3/5, respectively in Group 1, 2 and 3. Group 1 had the largest quantity of new bone measured by histopathological study and X-ray analysis, and at the 12th week, the medullary cavity in this group became united. The compress stiffness, torsion stiffness and the maximal load in Group 1 were better than those in other groups. Conclusion The tissue engineered bone contructed by PLGA scaffords that are loaded with 5 mg BMP and BMSCs is capable of repairing segmental bone defects.

目的以聚乳酸-羟基乙酸[poly-(D,L-lactide-co-glycolide),PLGA]为支架,负载不同浓度的骨形态发生蛋白(bonemorphogeneticprotein,BMP),与骨髓基质干细胞(bonemarrowstemcells,BMSCs)构建成新型的组织工程骨,并观察其体内成骨的量效关系。方法制作新西兰大白兔桡骨中段15mm骨缺损实验模型,植入不同含量BMP的组织工程骨。24只兔随机分为三组:第一组:植入同时负载5.0mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(10只);第二组:植入同时负载2.5mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(7只);第三组:植入同时负载1.0mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(7只)。术后对动物进行大体观察,摄X线片观察各组术后4、8、12周骨缺损修复情况,比较不同时相的骨缺损区X线阻射密度。于术后第4、8、12周取出骨缺损区标本进行大体观察和组织学切片观察,图像分析骨缺损区域骨小梁的生成数量;取第12周标本行生物力学检测。结果X线片显示术后4周三组动物的桡骨缺损区域均有明显骨...

目的以聚乳酸-羟基乙酸[poly-(D,L-lactide-co-glycolide),PLGA]为支架,负载不同浓度的骨形态发生蛋白(bonemorphogeneticprotein,BMP),与骨髓基质干细胞(bonemarrowstemcells,BMSCs)构建成新型的组织工程骨,并观察其体内成骨的量效关系。方法制作新西兰大白兔桡骨中段15mm骨缺损实验模型,植入不同含量BMP的组织工程骨。24只兔随机分为三组:第一组:植入同时负载5.0mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(10只);第二组:植入同时负载2.5mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(7只);第三组:植入同时负载1.0mgBMP及1×106个已向成骨细胞诱导的BMSCs的组织工程骨(7只)。术后对动物进行大体观察,摄X线片观察各组术后4、8、12周骨缺损修复情况,比较不同时相的骨缺损区X线阻射密度。于术后第4、8、12周取出骨缺损区标本进行大体观察和组织学切片观察,图像分析骨缺损区域骨小梁的生成数量;取第12周标本行生物力学检测。结果X线片显示术后4周三组动物的桡骨缺损区域均有明显骨痂生成;12周时三组的骨缺损完全愈合率分别为7/8、3/5、3/5;各时相局部X线阻射密度值与新生骨小梁百分比计量显示第一组的新生骨痂及骨小梁最多,并可见髓腔再通现象。生物力学检测结果显示第一组的压缩刚度、扭转刚度、三点弯曲断裂载荷均大于其他两组。结论含5.0mgBMP的PLGA支架与BMSCs复合构建的组织工程骨修复兔桡骨15mm骨缺损的效果最佳。

 
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