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   自身免疫性疾病 在 临床医学 分类中 的翻译结果: 查询用时:1.187秒
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自身免疫性疾病     
相关语句
  autoimmune disease
    autoimmune disease 47 cases(24.4%);
    自身免疫性疾病47例(24.4%);
短句来源
    Objective To evaluate the immunofluorescence assay(IFA) BIOCHIP reagent kit in the detection of antinuclear antibodies(ANA) in patients with autoimmune disease.
    目的 评价生物薄片免疫荧光技术 (BIOCHIP IFA)检测抗核抗体 (ANA)在自身免疫性疾病诊断中的应用价值。
短句来源
  autoimmune diseases
    Evaluation of Serum Anti-LSP in Viral Hepatitis and some Autoimmune Diseases
    对病毒性肝炎及某些自身免疫性疾病病人血清中抗肝特异性膜脂蛋白抗体(抗-LSP)的探讨
短句来源
    The determination of serum soluble CD4 and CD8 antigen in patients with autoimmune diseases
    自身免疫性疾病患者血清可溶性CD4、CD8的测定及临床意义
短句来源
    Results:28/40 were with dRTA, 13/28 with autoimmune diseases, 18/28 with hypokalemic paralysis, 3/28 with renal diabetes insibidus.
    结果:28/40为远端肾小管性酸中毒(dRTA),13/28合并其他自身免疫性疾病,18/28合并低钾性麻痹,3/28合并肾性尿崩症。
短句来源
    \ Methods\ ICA were measured by immunofluorescence method in 30 healthy subjects,30 patients with autoimmune diseases,37 IDDM and 30 NIDDM patients.
    方法用间接免疫荧光法对37例胰岛素依赖型糖尿病(IDDM)、30例非胰岛素依赖型糖尿病(NIDDM)及其他自身免疫性疾病、正常人对照组各30例进行ICA测定。
短句来源
    Conclusion Immunomodulatory effects of pregnancy at the cytokine level may be related to the variations in the clinical course of organ-specific,T cell-mediated autoimmune diseases during pregnancy.
    IL - 8m RNA表达水平的变化与孕妇体内 HCG水平变化相反。 结论 妊娠期间如患有器官特异性 T细胞介导的自身免疫性疾病 ,其疾病发展进程与孕妇体内细胞水平免疫调节的变化呈相关性
短句来源
更多       
  auto immune diseases
    Evaluation of Serum Anti-LSP in Viral Hepatitis and some Autoimmune Diseases
    对病毒性肝炎及某些自身免疫性疾病病人血清中抗肝特异性膜脂蛋白抗体(抗-LSP)的探讨
短句来源
    The determination of serum soluble CD4 and CD8 antigen in patients with autoimmune diseases
    自身免疫性疾病患者血清可溶性CD4、CD8的测定及临床意义
短句来源
    Results:28/40 were with dRTA, 13/28 with autoimmune diseases, 18/28 with hypokalemic paralysis, 3/28 with renal diabetes insibidus.
    结果:28/40为远端肾小管性酸中毒(dRTA),13/28合并其他自身免疫性疾病,18/28合并低钾性麻痹,3/28合并肾性尿崩症。
短句来源
    \ Methods\ ICA were measured by immunofluorescence method in 30 healthy subjects,30 patients with autoimmune diseases,37 IDDM and 30 NIDDM patients.
    方法用间接免疫荧光法对37例胰岛素依赖型糖尿病(IDDM)、30例非胰岛素依赖型糖尿病(NIDDM)及其他自身免疫性疾病、正常人对照组各30例进行ICA测定。
短句来源
    Conclusion Immunomodulatory effects of pregnancy at the cytokine level may be related to the variations in the clinical course of organ-specific,T cell-mediated autoimmune diseases during pregnancy.
    IL - 8m RNA表达水平的变化与孕妇体内 HCG水平变化相反。 结论 妊娠期间如患有器官特异性 T细胞介导的自身免疫性疾病 ,其疾病发展进程与孕妇体内细胞水平免疫调节的变化呈相关性
短句来源
更多       
  auto immune disease
    autoimmune disease 47 cases(24.4%);
    自身免疫性疾病47例(24.4%);
短句来源
    Objective To evaluate the immunofluorescence assay(IFA) BIOCHIP reagent kit in the detection of antinuclear antibodies(ANA) in patients with autoimmune disease.
    目的 评价生物薄片免疫荧光技术 (BIOCHIP IFA)检测抗核抗体 (ANA)在自身免疫性疾病诊断中的应用价值。
短句来源

 

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      autoimmune disease
    The development of lupus-like autoimmune disease of MRL/MpJ-lpr mice is an experimental model for study of autoimmune pathologies and immunopathogenesis.
          
    Multiple sclerosis is a chronic inflammatory, putatively autoimmune disease characterized by multifocal demyelination in the central nervous system.
          
    Systemic lupus erythematosus (SLE) is an autoimmune disease which occurs in over 80% in women during childbearing years.
          
    The association with thymoma and raised AChR antibody suggests that this syndrome represents a unique type of autoimmune disease, in which antibodies against the AChR facilitate rather than inhibit cholinergic action.
          
    The occurrence of a chronic inflammatory reaction in one of the two patients supports the idea that an autoimmune disease against GABA-ergic neurons may be involved in SMS.
          
    更多          
      autoimmune diseases
    The intermediate filament protein vimentin is a potential target antigen for autoantibodies in some infectious and autoimmune diseases.
          
    We measured the level of anti-vimentin antibodies in patients with systemic autoimmune diseases (n=42), healthy blood donors (n=58), and patients with acute inflammation and showing anti-vimentin immunofluorescence (n=50).
          
    There were no differences between the levels of anti-vimentin antibodies between patients with systemic autoimmune diseases and healthy individuals.
          
    At the same time it is becoming apparent that some remedies usually used to treat somatic and psychic disorders also have immunomodulating properties, and may help manage multiple sclerosis and other autoimmune diseases.
          
    Objective: Heat shock proteins (hsps) have been shown to be important antigens in a number of autoimmune diseases.
          
    更多          
      auto immune diseases
    MacKay and Burnet3 categorize the auto immune diseases in several main groups.
          
    These include certain viral infections, auto immune diseases and pregnancy.
          
      auto immune disease
    Electrochmemiluminescence has been applied today to a wide range of analytes of biological interest including thyroid and fertility hormones, infectious desease, as well as various markers of cardiac, malignant and auto immune disease.
          
    Trans fats are associated with auto immune disease, skin problems, growth problems in children and learning disabilities.
          
    There are difficulties with the idea of MS being primarily an auto immune disease.
          
    The presence of antibodies directed against the nucleus of the cell is a hallmark of auto immune disease.
          


    Serum thyroid autoantibodies from patients with nonthyroid diseases or autoi-mmune diseases have been examined by ELISA.The thyroid microsome antibody(TMAb) incidences of patients with systemic lupus erythematosus (SLE),insulindependent diabetes mellitus (IDDM) and nephrotic syndrome were significantly higherthan those of normal persons (P<0.01 or P<0.05).However,thyroglobulin antibody(TGAb) titer appeared significantly higher only in SLE group (P<0.05).Comparisonof serum autoantibodies of patients with nonthyroid...

    Serum thyroid autoantibodies from patients with nonthyroid diseases or autoi-mmune diseases have been examined by ELISA.The thyroid microsome antibody(TMAb) incidences of patients with systemic lupus erythematosus (SLE),insulindependent diabetes mellitus (IDDM) and nephrotic syndrome were significantly higherthan those of normal persons (P<0.01 or P<0.05).However,thyroglobulin antibody(TGAb) titer appeared significantly higher only in SLE group (P<0.05).Comparisonof serum autoantibodies of patients with nonthyroid diseases was made with thoseof patients with thyroid disease,and the clinical significance of detection of TMAband TGAb was discussed.

    用酶联免疫吸附试验(ELISA)方法对7种非甲状腺自身免疫性疾病或与自身免疫发病因素有关的疾病患者血清中 TMAb 和 TGAb 进行检测。其中 SLE,IDDM 及肾病综合征的TMAb 阳性率明显地高于正常人(P<0.01及 P<0.05),而 TGAb 水平只在 SLE 病患者中有意义(P<0.05)。本文结合与甲状腺疾病患者血清的检测结果的比较,初步探讨了临床上对多种疾病患者血清中 TMAb 和 TGAb 检测的意义。

    Indirect immunogold-silver staining ( IIGSS ) was applied to detect anti-nuclear antibodies ( ANA )in sera from 115 patients with autoimmune diseases, such as systemic lupus erythematosus, etc, and from 34 normal persons. The results were compared with those obtained simultaneously from indirect fluoresent antibody test ( IFAT ) . Forty-five of the 1^9 sera were found to be ANA positive by IIGSS, but 29 by IFAT. And doubtful results appeared in IFAT. However,2 doubtful results in IIGSS Further, the ANA titer...

    Indirect immunogold-silver staining ( IIGSS ) was applied to detect anti-nuclear antibodies ( ANA )in sera from 115 patients with autoimmune diseases, such as systemic lupus erythematosus, etc, and from 34 normal persons. The results were compared with those obtained simultaneously from indirect fluoresent antibody test ( IFAT ) . Forty-five of the 1^9 sera were found to be ANA positive by IIGSS, but 29 by IFAT. And doubtful results appeared in IFAT. However,2 doubtful results in IIGSS Further, the ANA titer for IIGSS was higher and the patterns of nuclear staining were clearer than those in IFAT. These results indicate that IIGSS. is highly specific, sensitive and reliable in detecting serai ANA. The patterns of nuclear staining with IIGSS are also mentioned in this paper.

    应用间接免疫金银染色(IIGSS)检测了系统性红斑狼疮等自身免疫性疾病病人及正常人血清中的抗核抗体(ANA),并与间接荧光抗体试验(IFAT)作了比较。在149份血清中IIGSS检出45份阳性,IFAT只检出29份阳性。IFAT有32份为可疑,IIGSS只有2份为可疑。且ANA滴度以IIGSS为高,核型显示以IIGSS更清楚。结果表明,IIGSS检测血清ANA特异性高,较IFAT更敏感、可靠、并能反映ANA组分。

    Detection of antibodies to thyroid microsomal antigen (TMAb) or thyroid peroxidase (TPO-Ab) has been widely used in the diagnosis of autoimmune thyroid diseases. Crude human TM contains thyroglobulin (TG) residue and other human membrane antigens so that the sensitivity of TMAb-ELISA may be affected. Highly purified TM was prepared by affinity chromatography and a sensitive TM-ELISA was developed. The intra-assay coefficient of variation was 3. 2±0. 01% (n = 80) and the interassay CV 8. 3±0.02% (n=8). The positivity...

    Detection of antibodies to thyroid microsomal antigen (TMAb) or thyroid peroxidase (TPO-Ab) has been widely used in the diagnosis of autoimmune thyroid diseases. Crude human TM contains thyroglobulin (TG) residue and other human membrane antigens so that the sensitivity of TMAb-ELISA may be affected. Highly purified TM was prepared by affinity chromatography and a sensitive TM-ELISA was developed. The intra-assay coefficient of variation was 3. 2±0. 01% (n = 80) and the interassay CV 8. 3±0.02% (n=8). The positivity rate for TMAb in the clinical hyperthyroidism was 80. 4% (n = 46). Compared to other assays developed at home,the positivity rate for TMAb in Graves' disease and Hashimoto's disease was raised by 20% and 11. 7%,respectively.

    甲状腺微粒体抗体(TMAb)或称甲状腺过氧化物酶抗体(TPO-Ab)已广泛用于人类甲状腺自身免疫性疾病的诊断,但粗提的人甲状腺微粒体制备物含有残留的甲状腺球蛋白(TG)和其它膜抗原,影响方法的灵敏度,我们采用亲和层析的方法,得到纯度较高的TM抗原,建立了灵敏的TMAb-ELISA。该方法的批内变异系数为3.2±0.01%(n=80),批间变异系数为8.3±0.02%(n=8);临床甲亢病人的阳性率为80.0%(n=46),与国内同类放免试剂盒相比,对Graves病的阳性检出率提高20%(n=20),桥本氏甲状腺炎的阳性检出率提高11.7%(n=26)。

     
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