Further research on the signaling pathway of B7-H4 provides a promising way to modulate the T cell-mediated immune response in autoimmune disease,virus infectious diseases,and rejection of organ transplantation,also offers a new strategy for diagnosis and treatment of tumor.
Our data suggest that urine β2-m,albumin and IgG levels measurement are valuable in cancer diagnosis and are sensitive parameters in observing renal function of cancer patients,provided other renal diseases and autoimmune disease can be excluded.
In particular, the clearance of intracellular bacteria, fungi and protozoa requires the induction of host-derived IFN-γ by IL-18. Involvement in the progression of pathogenicity in autoimmune diseases, chronic inflammatory diseases and allergic diseases was reported.
Conclusions TWH possesses apoptosis inducing effect on HL 60 cells. This effect of TWH is probably related to its immunosuppressive and clinical therapeutic effect on autoimmune diseases and its side effects.
The development of lupus-like autoimmune disease of MRL/MpJ-lpr mice is an experimental model for study of autoimmune pathologies and immunopathogenesis.
Multiple sclerosis is a chronic inflammatory, putatively autoimmune disease characterized by multifocal demyelination in the central nervous system.
Systemic lupus erythematosus (SLE) is an autoimmune disease which occurs in over 80% in women during childbearing years.
The association with thymoma and raised AChR antibody suggests that this syndrome represents a unique type of autoimmune disease, in which antibodies against the AChR facilitate rather than inhibit cholinergic action.
The occurrence of a chronic inflammatory reaction in one of the two patients supports the idea that an autoimmune disease against GABA-ergic neurons may be involved in SMS.
Electrochmemiluminescence has been applied today to a wide range of analytes of biological interest including thyroid and fertility hormones, infectious desease, as well as various markers of cardiac, malignant and auto immune disease.
Trans fats are associated with auto immune disease, skin problems, growth problems in children and learning disabilities.
There are difficulties with the idea of MS being primarily an auto immune disease.
The presence of antibodies directed against the nucleus of the cell is a hallmark of auto immune disease.
The intermediate filament protein vimentin is a potential target antigen for autoantibodies in some infectious and autoimmune diseases.
We measured the level of anti-vimentin antibodies in patients with systemic autoimmune diseases (n=42), healthy blood donors (n=58), and patients with acute inflammation and showing anti-vimentin immunofluorescence (n=50).
There were no differences between the levels of anti-vimentin antibodies between patients with systemic autoimmune diseases and healthy individuals.
At the same time it is becoming apparent that some remedies usually used to treat somatic and psychic disorders also have immunomodulating properties, and may help manage multiple sclerosis and other autoimmune diseases.
Objective: Heat shock proteins (hsps) have been shown to be important antigens in a number of autoimmune diseases.