In order to inquire into the curative effect of promethazine in the treatment of salivation produced by clozapine, 98 male patients who had salivation after singly taking clozapine were selected and treated with promethazine (25-50mg/day).
Results: After dogs were injected Polysorbate 80 liquor or the Chinese drug injection 5ml·kg-1 containing Polysorbate 80 17.5mg·kg-1,the irritability reactions such as fall of blood pressure,bradycardia,skin erythema,salivation,emesis,spasm and convulsion apperaed;
The b-e grade ptyalism in 15 c ase were improved to a-c grade after training, and the effective rate of ptyali sm was 100%, there was very significant difference before and after treatment( χ2=40, P< 0.01).
Among them, the symptom of 66 patients with strabismus , 30 patients with ptyalism, 72 patients with slurred speech, 78 patients with finger incoordination of grasp function and other concomitant disturbances had been improved to varying degrees , there were no operative complications.
However,patients in quetiapine group reported much fewer side effects than those in clozapine group,especially in the items of reduced activities,constipation,sialorrhea,dizziness and low blood pressure on TESS (P<0.01 or P<0.05).
The adverse reactions of quetiapine group; such as hypoactivity, blurred vision, constipation, sialorrhea, dizziness and increase of body weight were less than those of clozapine group( P <0.01 or P <0.05 ).
Objective To analyze the reason of the clinical improvement of spasticity of upper limbs and amelioration of strabismus, slobbering and cacophonia after the lumbar-sacral selective posterior rhizotomy(L-S SPR).
This paper introduces the productive process of the soluble plastic film. Then,it disserts the design principle of the mechanism for tension and adjusting deviation of slobbering machine forming membrane steel band which produces soluble plastic package film,and the application to SL-1200 slobbering machine.
Clinical symptoms were mainly: forced respiration, muscular tremor to tetanoid spasms, cyanosis of the skin, salivation and sometimes vomiting.
severe hyperaemia of the paretic half of the face during intense salivation in response to atropine.
Facial hyperaemia during intense salivation after atropine administration is explained as a result of the intensified release of vasoactive intestinal polypeptide from the gland, stimulated by atropine, into the blood circulation.
Urinary disturbance developed rapidly and was followed by orthostatic syncope, absence of lacrimation, salivation and sweating, and sensory impairment.
The patient complained mainly of decreased salivation, constipation, dry skin, and orthostatic intolerance.