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   移行细胞癌 在 妇产科学 分类中 的翻译结果: 查询用时:0.027秒
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移行细胞癌
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  transitional cell carcinoma
Nephroureterectomy with removal of a bladder cuff was performed successfully on a 47-year-old man for transitional cell carcinoma of the right renal pelvis using hand-assisted laparoscopy.
      
Alteration of G1-cyclins (D1 and E) in transitional cell carcinoma of human urinary bladder with infection of HPV-18
      
Objective: This study was designed to investigate differential pattern of G1-cyclins (D1 and E) in transitional cell carcinoma (TCC) of human urinary bladder with or without human papillomavirus-18 (HPV-18) infection.
      
Recurrence risk factors in patients with transitional cell carcinoma of bladder
      
Methods: An analysis on recurrence-related factors was made by Cox's proportional hazards model analysis and logistic multiple linear regression model analysis in 212 patients with transitional cell carcinoma treated surgically from 1995~2001.
      
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Biopsy of transitional cell carcinoma of urinary bladder taken before and after photodynamic therapy (PDT) from 15 patients were examined by electron microscopy. It has been demonstrated that this tumor is highly sensitive to PDT using hematoporphyrin derivative (HPD, China-made) and laser irradiation. Within the tumor tissues, the capillaries are most sensitive to PDT action, displaying distinct injuries of endothelium immediately after 20 minutes irradiation. 24 h after PDT, almost all capillaries became necrotic....

Biopsy of transitional cell carcinoma of urinary bladder taken before and after photodynamic therapy (PDT) from 15 patients were examined by electron microscopy. It has been demonstrated that this tumor is highly sensitive to PDT using hematoporphyrin derivative (HPD, China-made) and laser irradiation. Within the tumor tissues, the capillaries are most sensitive to PDT action, displaying distinct injuries of endothelium immediately after 20 minutes irradiation. 24 h after PDT, almost all capillaries became necrotic. The cancer cells are less sensitive to PDT, showing destruction later and less serious as compared with that of capillaries. 4 days after PDT, the cancer tissue became completely necrotized. 3 weeks and 80 days after PDT, the tumor bed was still covered with necrotic debris. It is concluded that in PDT treated tumors, the capillary endothelium will be primarily damaged while destruction of cancer cells be mainly caused by structural and functional changes in microcirculation.

电镜观察15例光动力学治疗前后膀胱移行细胞癌的活检材料,证实此治疗对膀胱癌有显著作用。肿瘤组织内的毛细血管对光动力学作用最为敏感,照光20min后即出现明显损伤,24h后,毛细血管几乎完全坏死崩解。癌细胞的破坏出现较晚,迟于毛细血管。治疗4d后肿瘤组织水肿、出血,几全部坏死。治疗21~80d后,瘤床仍水肿并有出血及坏死物质复盖。表明血管的结构损伤与功能障碍在肿瘤光动力学治疗机理中起主要作用。

Cytokeratin and Carcinoembryonic Antigen (CEA) in bladder cancer cells were studied in 28 and 26 cases respectively using Avitin-Biotin-peroxidase Complex (ABC) method. The results showed that the low molecular weight cytokeratin and CEA expressed during the embryo development were also expressed in transitional cell carcinomas. Both were increased with the increase of pathological grade and de- creased with degree of cancer cell differentiation. It is suggested that tha differences of both cytokeratin and CEA...

Cytokeratin and Carcinoembryonic Antigen (CEA) in bladder cancer cells were studied in 28 and 26 cases respectively using Avitin-Biotin-peroxidase Complex (ABC) method. The results showed that the low molecular weight cytokeratin and CEA expressed during the embryo development were also expressed in transitional cell carcinomas. Both were increased with the increase of pathological grade and de- creased with degree of cancer cell differentiation. It is suggested that tha differences of both cytokeratin and CEA in the different pathological grading of bladder car- cinoma might be an index related to the differentiation of cancer cell. The results also showed that by using higher sensitive method and specific antibody, the antigen of cancer cell may be demonstrated well in formalin-fixed, fresh or older, paraffin- embedded tissues.

本文应用ABC免疫过氧化酶技术分别对28例和26例膀胱癌细胞角蛋白和癌胚抗原进行了检查。结果表明,移行细胞癌随着细胞分化程度的降低,于胚胎发育过程及正常上皮细胞成熟过程早期表达的部分基因,在膀胱癌细胞内重新表达或表达失常,从而影响细胞的分化;不同病理组织学分级的膀胱癌细胞内角蛋白含量的差异,可作为癌细胞分化程度的一项指标。本文还提出,应用高敏感性的方法及高特异性抗体仍可较好地检测出福尔马林固定、石蜡包埋的新鲜或陈旧的组织中癌细胞的抗原性。

The volume weighted mean nuclear volumes of the transitional cancer of blad-ders were estimated and a good correlation between the mean Vo lume and thegradings was present.

本文对不同病理分级的膀胱移行细胞癌的癌细胞核的体积加权平均体积作了初步的回顾性研究,该平均体积与病理分级成正相关关系。并说明在癌细胞的病理诊断中有重要意义。

 
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