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低剂量     
相关语句
  low dose
    Molecular Mechanism and Modulation of Low Dose Mitomycin C That Induces Bladder Cancer Cell Apoptosis and Inhibits Proliferation
    低剂量丝裂霉素诱导膀胱癌细胞凋亡和抑制增殖的分子机制及调控
短句来源
    PRELIMINARY STUDY ON CHROMOSOME DAMAGE INDUCED BY LOW DOSE X-RAYS IN SECONDARY OOCYTES OF MICE
    小剂量低剂量率X射线诱发小鼠卵母细胞染色体畸变的研究
短句来源
    ULTRASTRUCTURE FEATURES OF DIPLOID CELL OF HUMAN EMBRYO LUNG IN VITRO UNDER LOW DOSE OF CARCINOGEN
    低剂量苯并芘作用下传代培养人胚肺二倍体细胞的超微结构特征
短句来源
    Inhibitory effect of low dose radiation on the implanted tumor and its influence on genetic
    低剂量辐射对种植肿瘤的抑制作用及其对遗传物质的影响
短句来源
    Treatment of Cutaneous Hemangioma with Low Dose Superficial X-ray
    低剂量X线治疗皮肤血管瘤
短句来源
更多       
  low-dose
    Early detection of central lung cancer:preliminary study with low-dose spiral CT
    低剂量螺旋CT早期检出中央型肺癌的初步研究
短句来源
    The Experimental and Clinica Studies of Low-dose Cyclophosphamide Combined with Ginsenoside Rg3 on Advanced Non-small Cell Lung Cancer
    低剂量环磷酰胺联合人参皂甙Rg3治疗晚期非小细胞肺癌的实验及临床研究
短句来源
    A SIMPLIFIED CALCULATION FOR TDF OF MULTIPLE FRACTIONS LOW-DOSE RATE BRACHYTHERAPY
    多次低剂量率腔内治疗的时间、剂量因子(TDF)简易计算法
短句来源
    MethodsThe 40 enrolled patients with AML were randomly divided into experimental and control groups. The experimental group(n=21)was given rhG-CSF combined with low-dose TA /NA chemotherapy,the control group(n=19)was given the standard dose of TA/NA chemotherapy.
    方法40例初治、复发的AML患者随机分为实验组和对照组,实验组21例采用rhG-CSF联合低剂量方案诱导化疗,对照组19例采用标准剂量的TA/NA方案诱导化疗。
短句来源
    ConclusionrhG-CSF combined with low-dose TA/NA chemotherapy has comparable curative effect and less side effects as compared with standard TA/NA regimen,yet can shorten the length of hospitalization without increase of costs.
    结论rhG-CSF联合低剂量TA/NA方案治疗AML的CR率和总有效率与标准剂量的化疗方案疗效相当,其毒副作用较轻,并可减少住院时间及缩短中性粒细胞的减低时间,而不增加住院费用。
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  low does
    Clinical Efficacy and Adverse Effects of Weekly Dose of Paclitaxel Combined with Low Does of FP Regimen in the Treatment of 22 Patients with Advanced Gastric Cancer
    周剂量紫杉醇联合低剂量FP方案治疗晚期胃癌临床观察
短句来源
    Effect of low does irradiation on expression of DNA repair genes and ceD cycle of A549 and 2BS cells
    低剂量照射对细胞周期和修复基因表达的影响
短句来源
    It was found that apoptosis is the main pattern of HL 60 cell death induced by low does VP 16 in a short time, and it can be suppressed when protein kinase C(PKC) is activated.
    结果显示 ,低剂量VP 16短时间作用HL 6 0细胞 ,细胞的死亡以凋亡为主 ,并可被蛋白激酶C(PKC)激活所抑制 ;
短句来源
    Objective To investigate the effect of low does irradiation on expression of DNA repair genes and cell cycle of A549 and 2BS cells.
    目的观察低剂量照射对A549(肺癌细胞)和2BS细胞(人胚胎肺成纤维细胞)细胞周期及修复基因表达的影响。
短句来源
  low level exposure
    The Role of Biomarker in Risk Assessment of Low level Exposure of Carcinogen
    生物标志物在低剂量致癌物暴露危险度评价中的作用
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      low dose
    Maximum values of the growth index and specific growth rate, determined for dry biomass, were observed at a low dose of irradiation (0.2 W/m2) and an exposure of 3 h.
          
    The influence of high and low doses of cisplatin and its low dose in combination with ecdysterone on the dynamics of protein and DNA biosynthesis in the liver, pancreas, thymus, spleen, and adrenals of tumor-bearing mice were also studied.
          
    The ultra-low dose of the drug seems promising as a prophylactic agent.
          
    An effect of low dose (3 Gy) of irradiation on the accessibility of amino acid residues has been unequivocally demonstrated.
          
    A low dose of CG (10 IU/ml) increased the spontaneous apoptosis of neutrophils, whereas its combination with estradiol and progesterone corresponding to that of trimester III of pregnancy significantly decreased this parameter.
          
    更多          
      low-dose
    The mechanism of low-dose long-term exposed to SO2 is more complex.
          
    Elevated Micronucleus Frequency in Bone Marrow Erythrocytes in the Progeny of Male Mice Exposed to Chronic Low-Dose Gamma Irradi
          
    The micronucleus frequency in bone marrow erythrocytes from the F1 progeny of male mice exposed to chronic low-dose γ-irradiation was determined.
          
    Low-Dose Latrotoxin Effects on Behavior in White Rats
          
    This allowed us to estimate the contribution of extremely low-dose gamma-irradiation into the mutagenic effect, which was impossible under routine conditions.
          
    更多          
      low does
    Blood pressure control-Effects on diabetic nephropathy progression: How low does blood pressure have to be
          
    The answer to the question of how low does blood pressure have to be to minimize the effects of blood pressure on diabetic nephropathy progression might be "the lower, the better."
          
    "Live high, train low" does not change the total haemoglobin mass of male endurance athletes sleeping at a simulated altitude of
          
    Calli ofNicotiana tabacum (tobacco) were treated with two dose ranges of aflatoxin B1 (0.1-2.0 μg ml-1 - low does; 5-25 μg ml-1 aflatoxin B1).
          
    The Aleutian low does not extend as far east as observed and the high pressure ridge over northern Africa is too strong.
          
    更多          
      low level exposure
    Some mechanisms are described by which selenium, vitamin E, and other factors might facilitate MeHg breakdown to inorganic Hg during long term low level exposure to MeHg.
          
    After subchronic (90 days) low level exposure there was a more pronounced effect on activation of the alveolar macrophages, with increased phagocytic activities.
          
    These results suggest that the NMDA receptors in the mouse brain are sensitive to relatively low level exposure to TBTCl.
          
    Es wird diskutiert, ob es sich bei den beobachteten mitoseabh?ngigen Zellatypien um Sp?tfolgen einer sogenannten "low level exposure" handeln k?nnte.
          
    Also, in spite of the favourable excretion kinetics, the impact of smoking and the large interindividual variation warrant the same conclusion for o-cresol as a means of monitoring low level exposure in an individual worker.
          
    更多          


    The dinitrosopiperazine (DNP) in its subthreshold dose was used as an initiator and Niso4 gel (Ni-gel) or Niso4 water solution (Ni-water) as a promotor in inducing NPC in rats. In the experiment four groups, namely, DNP + Ni-gel, DNP + Ni-water, Ni-gel and DNP, were designed. The results showed that five carcinomas were found in 22 rats of the DNP + Ni-gel experimental group and no carcinoma developed in the other three groups. This demonstrated that nickel sulfate may be recognised as a promotor in inducing...

    The dinitrosopiperazine (DNP) in its subthreshold dose was used as an initiator and Niso4 gel (Ni-gel) or Niso4 water solution (Ni-water) as a promotor in inducing NPC in rats. In the experiment four groups, namely, DNP + Ni-gel, DNP + Ni-water, Ni-gel and DNP, were designed. The results showed that five carcinomas were found in 22 rats of the DNP + Ni-gel experimental group and no carcinoma developed in the other three groups. This demonstrated that nickel sulfate may be recognised as a promotor in inducing NPC which had been reported previously by the authers themselves.Among the five carcinomas 2 occured in the nasopharynx (carcinoma in situ and early squamous cell carcinoma), 2 in the nasal cavity (undifferentiated carcinoma and squamous cell carcinoma) and 1 on the hard palate (Squamous cell carcimoma). It is worthwhile to point out that the carcinomas induced by the application of subthreshold dinitrosopiperazine and nickel sulfate developed not only in the nasopharynx but in the nasal cavity as well as hard palate also. This finding reveals that though the dinitrosopiperazine has the affinity to the nasopharynx for carcinogenesis, the nasal cavity and hard palate may alco be the sites to be affected.

    本文报导我们再次应用一次低剂量的二亚硝基哌嗪作为起动因子,用硫酸镍作为促动因子,进行诱发大鼠鼻咽癌的实验。将90只成年大鼠分为四组,即:二亚硝基哌嗪+镍胶组,二亚硝基哌嗪+镍水组,镍胶组和二亚硝基哌啼组。实验进行270天以后,将全部大鼠处死作病理检查。结果表明,在二亚硝基哌嗪+镍胶组的22只大鼠中,有5例发生恶性肿瘤(鼻咽原位鳞癌和早期鳞癌各1例,鼻腔未分化癌和鳞癌各1例,硬腭鳞癌1例),其它组则未见肿瘤发生。这再次表明,微量元素镍在诱发大鼠鼻咽癌中有促癌作用。 本实验还表明,肿瘤不仅发生在鼻咽,而且也发生在鼻腔和硬腭,因此,二亚硝基哌嗪不仅对鼻咽有亲合力,对鼻腔和硬腭也是有亲合力的。

    The mechanism of action pseudolycorine has been studied in Erhrich Ascites carcinoma (EAC) by the incorporation of 3H-pseudolycorine, 3H-TdR, and 3H-UR. It was shown that the radioactivity detected in DNA of EAC cells was about 68% of total amount of 3H-pseudolycorine in the cancer cells. It was shown that pseudolycorine caused a definite inhibition on DNA biosynthesis in a lower dose level and possessed some depressive action on RNA biosynthesis in a higher dose level. In pseudolycorine treated EAC cells, the...

    The mechanism of action pseudolycorine has been studied in Erhrich Ascites carcinoma (EAC) by the incorporation of 3H-pseudolycorine, 3H-TdR, and 3H-UR. It was shown that the radioactivity detected in DNA of EAC cells was about 68% of total amount of 3H-pseudolycorine in the cancer cells. It was shown that pseudolycorine caused a definite inhibition on DNA biosynthesis in a lower dose level and possessed some depressive action on RNA biosynthesis in a higher dose level. In pseudolycorine treated EAC cells, the incorporation of 3H-TdR into EAC cells was inhibited, however, the incorporation rates tended to increase in various time after the removal of pseudolycorine, showing a progressively increasing curve. This suggested that pseudolycorine did not induce a permanent destruction of DNA structure, otherwise it might be intercalated into the DNA moleculer to interfere with the DNA biosynthesis.

    应用~3H标记的伪石蒜碱、脱氧胸苷及尿苷参入作用在艾氏腹水癌(EAC)研究了伪石蒜碱的作用机理。已证明癌细胞中测得~3H-伪石蒜碱的量68%在其细胞DNA中。已证明伪石蒜碱在较低剂量下可引起DNA合成的肯定的抑制,而在较高浓度下才抑制RNA合成。在伪石蒜碱处理的EAC细胞中,~3H-脱氧胸苷参入EAC细胞受抑制,除去伪蒜石碱后不同时间内,渗入率倾向于增加,形成递增型曲线,这提示伪石蒜碱不引起DNA结构的永久性破坏。反之,它可能嵌入DNA分子中,而干扰DNA的生物合成。

    TEA determination of nitrosamine was performed in the homemade FS from the prevalent area of esophageal cancer. Seven out of eight samples were positive. Nitroso-diethylamine was detected in six samples.It is as high as 6.83ppb in some samples.Urine nitrosamine was determined. The amount of nitrosamine in the uri.....ne of persons after taking FS increased from 3.16±0.972 ppb to 5.75±2.72 ppb- No inhibitory effect was obereved when low dose Vit-C was given simultaneously.In order to provide preventive guide...

    TEA determination of nitrosamine was performed in the homemade FS from the prevalent area of esophageal cancer. Seven out of eight samples were positive. Nitroso-diethylamine was detected in six samples.It is as high as 6.83ppb in some samples.Urine nitrosamine was determined. The amount of nitrosamine in the uri.....ne of persons after taking FS increased from 3.16±0.972 ppb to 5.75±2.72 ppb- No inhibitory effect was obereved when low dose Vit-C was given simultaneously.In order to provide preventive guide to the prevalent area of esophageal cancer, other preventive measures are being searched for.

    本文初步报道食管癌高发区民用、家制鱼露内含亚硝胺的情况:8种样品中7种阳性,6种能检出二乙基亚硝胺,有的高达6.83ppb。人服用高发区民用鱼露体内代谢尿中的亚硝胺亦有较大改变:眼前:3.16±0.972ppb,服后:5.75±12.72ppb。低剂量的维生素C尚无阻断作用。我们正在进一步寻找阻断的方法,为食管癌高发区提供预防方案。

     
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