Effects of stress on myocardial nutritional blood flow (NBF), oxygen free radical (OFR)concentration, superoxide dismutase (SOD) activity and malondialdehyde (MDA) content of aged mice were studied for exploring the mechanism by which the aged heart is damaged by stress reaction.
The results show that the antioxidants all possess the scavenging capacities on oxygen radicals to some extent. The IC50 of scavenging for V-C,catechin and the extraction from Glyeyrrhize uralensis are respectively 2.04 g/mL,6.16 g/mL and 42.13 g/mL;
Conclusions Celecoxib provided protection against CIRI possibly by reducing the accumulation of PGE2,the production of oxygen radicals,altering the ration between TXB2 and 6-K-PGF1α and increasing the activity of SOD.
Reactive oxygen radicals generated in ammonium perfullate (AP) and N, N, N', N'-tetramethyl ethylenediamine (TEMED) system measured directly by ESR methods. It was studies that the effect of O2-·and HO·radicals in the system were scavenged by some drinks.
Among many pathogenic factors, the changes of vasoactive substances, participation of inflammatory mediators as well as OFR (oxygen free radical), endotoxin, etc.
Oxygen free radical damage of isolated cardiomyocytes: comparative protective effect of radical scavengers and calcium antagonis
Oxygen free radical formation has been implicated in lesions caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and iron.
It was found that after 20 minutes ischemia, the first peak of oxygen free radical appeared at about 0.5 minutes after the beginning of reperfusion, then the release of oxygen free radicals decreased with time.
Protective effect of carvedilol on abnormality of L-type calcium current induced by oxygen free radical in cardiomyocytes
During daytime, when temperature is high, the soluble sugar does not participate in the osmotic adjustment but eliminate the active oxygen free radicals.
Retrograde infusion of chondroitin-sulfate via pancreatic duct could alleviate the pancreatic cell damage as a sort of scavengers of oxygen free radicals.
The main target for ultrasound-generated oxygen free radicals were cystine residues oxidized to cysteic acid residues.
Oxygen free radicals appear to impair not only lens crystallins which will aggregate and precipitate forming opacities but also proteolytic enzymes whose function it would be to eliminate the damaged proteins.
No evidence of oxygen free radicals-mediated damage during the calcium paradox
Water-borne raspberry-like PMMA/SiO2 nanocom-posite particles were prepared via free radical copolymerization of methyl methacrylate (MMA) with 1-vinylimidazole (1-VID) in the presence of ultrafine aqueous silica sols.
Graft copolymers of hydroxylethyl cellulose (HEC) and PAA were prepared by free radical polymerization.
Results showed that the process has good characteristics of living free radical polymerization, i.e.
time both were linear indicating that the reaction was a controlled/living free radical polymerization.
Results showed that the process had some of the good characteristics of controlled/living free radical polymerization.