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  cytologist
Performing bone biopsy and aspiration cytology by radiologist and cytologist in co-operation has proven highly accurate in diagnosing bone lesions.
      
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The man after whom it is named was not a cytologist engaged in studying the inner structure of the cell, but a pathologist searching to prove a neuroanatomical theory.
      
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In view of the great variation in the size of epithelial cell nucleic in benign changes in the mammary gland, the cytologist is often faced with diagnostic difficulties.
      
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The purpose of this paper is to provide cytologists and experts in hematologywith the methodology of analysing and studying cells through quantitative descrip-tions of various features of cell images given by computers.These quantitative descrip-tions also provide foundations for automatic classification of cell images and know-ledge expression of scene understanding in the research of pattern recognition.Through analysis of cell images,we have calculated 190 features that include 24optical density features,106...

The purpose of this paper is to provide cytologists and experts in hematologywith the methodology of analysing and studying cells through quantitative descrip-tions of various features of cell images given by computers.These quantitative descrip-tions also provide foundations for automatic classification of cell images and know-ledge expression of scene understanding in the research of pattern recognition.Through analysis of cell images,we have calculated 190 features that include 24optical density features,106 geometric features and 60 texture features.

本文旨在用计算机来定量地描述细胞图象的各种特征,为细胞学家和血液病专家提供对细胞分析研究的手段,也为在模式识别研究中对细胞自动分类和景物理解的知识表达提供依据。通过对细胞图象的定量计算,得到190个特征参数,其中有24个光密度特征参数,106个几何形状特征参数和60个纹理特征参数。

FNA cytologic diagnosis was performed in 10,816 patients with breast disease at the Section of Cytology, Tianjin Cancer Institute from July 1978 to June 1986. Of these, 3,541 patients were managed by surgery and the breast specimen examined histologically as control.The accuracy of cytologic diagnosis in malignancy was 89% and that of benign disease 90%. The overall false negative report was 6.8%. Accuracy was limited by the technique itself in small and deeply seated tumors. Negative reports also were due to...

FNA cytologic diagnosis was performed in 10,816 patients with breast disease at the Section of Cytology, Tianjin Cancer Institute from July 1978 to June 1986. Of these, 3,541 patients were managed by surgery and the breast specimen examined histologically as control.The accuracy of cytologic diagnosis in malignancy was 89% and that of benign disease 90%. The overall false negative report was 6.8%. Accuracy was limited by the technique itself in small and deeply seated tumors. Negative reports also were due to insufficient epithelial material for evaluation in the smear. The identification of cancer cells that are uniform in size and shape was frequently a problem even to the experienced cytologist, particularly in small cell cancer and those of well differentiated malignancies. It is also diffieult to make accurate diagnosis of a FNA smear under ordinary microscope. The cytologic criteria for diagnosing breast specimen were presented.

自1978年7月至1986年6月,天津市肿瘤研究所细胞学室共作乳腺疾患针吸细胞学诊断10,816例。其中有3,541例作了手术及组织学检查,以此为对照,细胞学诊断为恶性准确率的89%,良性乳腺疾患之细胞学诊断准确率为90%,假阴性报告为6.8%。细胞学诊断之准确性受技术性限制,如针吸时错过小的病变及深部肿瘤,涂片标本上皮成分不足等造成诊断困难,即使对有经验的细胞学家来说,仅凭细胞分化良好,形态单一去鉴别良、恶性也常有失误,本文对此进行了初步探讨。

 
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