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     ObjectiveTo investigate the effects of hypoxia-ischemia(HI)on neural stem cells(NSCs), neurons, glial cells(astrocytes, oligodendrocyte progenitors and microglia cells )in human fetal SVZ and compare the different survivabilities of SVZ cells to HI,thus to explore the pathogenesis of hypoxic-ischemic brain damage (HIBD) on the cellular lever.
     目的研究缺氧缺血(hypoxic ischemic, HI)对妊娠中期人类胚胎脑脑室管膜下区(subventricular zone, SVZ)神经干细胞(neural stem cells,NSCs)、神经元、神经胶质细胞(星形胶质细胞、少突胶质祖细胞和小胶质细胞)的影响,比较不同细胞对HI损伤的耐受性差异,揭示缺氧缺血脑损伤(Hypoxic-ischemic brain damaged , HIBD)及其它发育脑损伤性疾病的多种脑功能障碍表现的细胞学基础。
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     Results, nestin positive cells were found in the hippocampus, striatum and under ependymal of the embryonic human brain we observed, of which gestation weeks were 16W 17W 20+3W 22 W 23W 24+5W 25W 27W .
     结果发现分别在 166、17w、2000、222、23W、24吁、25W、27W胎)L的胎脑脑室管膜下区或海马或纹状体可见Nestin阳性细胞表达,且不同胎龄不同部位Nestin阳性细胞数量不一。
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     Conclusion IL-1 β and TNF-α may play a role in producing injury in infectious brain edema. The contents of IL-1 β and TNF-α related to activation of NF-κB.
     结论 脑组织中 IL-1β、TNFα含量显著增加与感脑脑损害有关 ,其 IL- 1β、TNFα含量增多与 NF- κB活性增加相关。
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     ③Determination of cerebral infarction volume:Every 6 rats were executed with narcotic overdose at 24,48 and 72 hours after reperfusion,respectively.
     ③脑梗死体积测定:于再灌注后24,48,72h将大鼠过量麻醉处死、取脑,脑片经红四氮唑染色,多聚甲醛固定;
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     The purpose of this study was to evaluate the effect of NAC on lipopolysaccharide (LPS)-sensitized neonatal rat hypoxia ischemia (HI) brain injury and possible mechanisms except the antioxidant effect.
     本研究将NAC应用于已经建立的内毒素(LPS,lipopolysaccharide)增敏新生大鼠缺氧缺血性(HI)脑损伤模型,探讨NAC对未成熟脑脑损伤的影响和作用机制。
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     brain
    
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     Hemangioreticuloma of the Brain
     血管网状细胞瘤
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OX-BB creatine kinase was purified

本文报道了用乙醇、硫酸铵分级,然后用磷酸纤维素、DEAE-纤维素离子交换柱层析以及Sephadex G-100凝胶过滤等方法,提纯了牛脑脑型肌酸激酶。酶制剂比活性提高约33倍,活力回收0.72%。在聚丙烯酰胺凝胶电泳染色,只显示一个区带。

The methods of continuous arterio-venous perfusion and clearing of thick section were applied. Under SXP-1 steromicroscope. the morphology, location, origin, type, drainage of the superficial veins and the outlet of the internal pontine veins of 27 adult fresh pons among which internal veins of 10 adult pons were observed. The superficial pontine veins include the anteromedian pontine vein, the anterolateral pontine vein, the lateral pontine vein, the superior transverse pontine vein and the inferior transverse...

The methods of continuous arterio-venous perfusion and clearing of thick section were applied. Under SXP-1 steromicroscope. the morphology, location, origin, type, drainage of the superficial veins and the outlet of the internal pontine veins of 27 adult fresh pons among which internal veins of 10 adult pons were observed. The superficial pontine veins include the anteromedian pontine vein, the anterolateral pontine vein, the lateral pontine vein, the superior transverse pontine vein and the inferior transverse pontine vein. The internal pontine anteromedian, anterolateral, lateral and posterior veins and their long veins, short veins and peripheral small veins were also discribed and discussed.

用动—静脉连续灌注和厚切片透明法,在SXP-1手术显微镜下观察了27个(54侧)新鲜成人脑的脑桥浅静脉和其中的10个脑桥内部静脉的形态、位置、起源、类型、汇流和内部静脉穿出点。脑桥浅静脉包括脑桥前正中静脉、脑桥前外侧静脉、脑桥外侧静脉。脑桥上横静脉和脑桥下横静脉。对脑桥内部的前内、前外、外侧和后静脉及其长静脉、短静脉和周边小静脉作了描述与讨论。

HRP was injected into the cervical(I-group)and lumbar enlargement (II-group) spinal cord unilaterally in pigs. The origins of the reticulo-spinal tracts in the medulla oblongata and pons were studied. In group-I, labeled cells were found in reticular formations of the medulla oblongata and pons. The numbers of labeled cells of nuclei were found as. GC>CV>Poo>Poc>Pmv>Cd>Pc, in group-II, the numbers were found as: GC>Poc>CV>Poo>Pmv>Cd. These cells were mainly found in the ipsilateral, only a few in the contralateral....

HRP was injected into the cervical(I-group)and lumbar enlargement (II-group) spinal cord unilaterally in pigs. The origins of the reticulo-spinal tracts in the medulla oblongata and pons were studied. In group-I, labeled cells were found in reticular formations of the medulla oblongata and pons. The numbers of labeled cells of nuclei were found as. GC>CV>Poo>Poc>Pmv>Cd>Pc, in group-II, the numbers were found as: GC>Poc>CV>Poo>Pmv>Cd. These cells were mainly found in the ipsilateral, only a few in the contralateral. Labeled cells were mainly observed in the magnocelluar part of the bulbopontine reticular formation in the medial part of the tegmentum, a few of them in the lateral part of the tegmentum. In both groups, labeled cells in the bulbar reticular formation were more than that of pons.

将HRP注射于猪脊髓颈膨大(第一组),或腰膨大(第二组)一侧灰质,逆行追踪了延脑和脑桥网状结构向脊髓投射的起源部位。在延脑、脑桥网状结构中第一组出现的标记细胞数GC>CV>Poo>Poc>Pmv>Cd>Pc,第二组GC>Poc>CV>Poo>Pmv>Cd,两组各核团标记细胞数同侧多于对侧。标记细胞主要分布在网状结构内侧大细胞部,外侧小细胞部也发现了标记细胞。两组的延脑网状结构中出现的标记细胞皆多于脑桥。

 
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