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结肠纤维镜
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AIM:To conclude the clinical characteristics of multiple primary colorectal carcinoma(MPCC). METHODS:The clinical data of 42 patients with MPCC out of 1354 primary colorectal cancer cas- es,who were treated in our hospital from 1980 to 2005,were retrospectively analyzed. RESULTS:The percentage of patients with MPCC was 3.10%(synchronous:0.96%;meta- chronous:2.14%).Of the 42 cases,20(1.48%) were accompanied by carcinoma of other or- gans.Adenocarcinoma was the most common cancer,locating at the right colon(46.3%)and...

AIM:To conclude the clinical characteristics of multiple primary colorectal carcinoma(MPCC). METHODS:The clinical data of 42 patients with MPCC out of 1354 primary colorectal cancer cas- es,who were treated in our hospital from 1980 to 2005,were retrospectively analyzed. RESULTS:The percentage of patients with MPCC was 3.10%(synchronous:0.96%;meta- chronous:2.14%).Of the 42 cases,20(1.48%) were accompanied by carcinoma of other or- gans.Adenocarcinoma was the most common cancer,locating at the right colon(46.3%)and rectum(31.3%).The tumors of other organs were mainly located at stomach,small intestine, breast,ovary and uterus.The data of 12 cases (12/42,28.6%)were in accordance with Am- sterdam criteriaⅡfor hereditary nonpolyposis colorectal cancer(HNPCC),and the data of 16 cases(16/42,37.2%)were in accordance with the Chinese criteria for HNPCC.Colon fiberscopy was helpful in the diagnosis of MPC. CONCLUSION:MPCC,with a high incidence rate,has particular epidemic,clinical and pathological characteristics.Colon fibers- copy is important in the diagnosis of MPC, and postoperative following up should be strengthened for the diagnosis of HNPCC.

目的:探讨大肠多原发癌及其肠外器官恶性肿瘤的流行病学、临床病理特点及诊治方法.方法:对我院1980-2005年收治的42例大肠多原发癌及其肠外恶性肿瘤的临床、病理及随访资料进行回顾性分析.结果:本组病例占我院同期收治的所有大肠癌的3.10%(42/1354),其中同时性大肠多原发癌13例(0.96%);异时性大肠多原发癌29例(2.14%);合并肠外器官恶性肿瘤的有20例(1.48%).大肠癌灶以右半结肠和直肠为多,肠外癌灶以胃、小肠、乳腺、卵巢、子宫为多;病理均以腺癌为主.共有12例(28.6%)符合遗传性非息肉病性大肠癌(HNPCC)阿姆斯特丹标准Ⅱ,16例(37.2%)符合中国人HNPCC诊断标准.结肠纤维镜检查有助于多原发癌的检出.结论:大肠多原发癌的发病率较高,其流行病学和临床病理特点突出.应注意重视结肠纤维镜检查,术中应仔细全面探查,加强术后随访有助于HNPCC的发现和诊断,以避免误诊漏诊.

 
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