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肌汁
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     Positive rate of biliary bacterial culture in hepatolithiasis paitents was significantly higher than that in gallstone paitents (65.7% vs 18.5% , P <0.05).
     胆管结石患者的肌汁细菌培养阳性率(65.7%)高于胆囊结石患者的胆汁细菌培养阳性率(18.5%)。
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     Study on the Preparation Of the Juice Of Carrots
     胡萝卜的研制
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     Peroneal Muscular Atrophy
     腓骨萎缩症
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     THE DEVELOPMENT OF CHINESE CHIVE JUICE
     韭菜的研制
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     ② Muscular wet weight.
     ②湿重。
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Objective To investigate the epidemiological characteristics of gallstone disease in Haiman Province. Methods 135 patients with gallstone from September 1991 to December 1997 were analyzed retrospectively. The clinical and epidemiological data were collected, and the composition of gallstone was determined. Results 51.9% of cases wefe hepatolithiasis and cholesterol stone was about 65.7% . The incidence of gallstone was higher in city residents, obese patients and those with high lipid intake. The incidence...

Objective To investigate the epidemiological characteristics of gallstone disease in Haiman Province. Methods 135 patients with gallstone from September 1991 to December 1997 were analyzed retrospectively. The clinical and epidemiological data were collected, and the composition of gallstone was determined. Results 51.9% of cases wefe hepatolithiasis and cholesterol stone was about 65.7% . The incidence of gallstone was higher in city residents, obese patients and those with high lipid intake. The incidence of hepatolithiasis was higher in patients in rural areas and those with low lipid intake. Positive rate of biliary bacterial culture in hepatolithiasis paitents was significantly higher than that in gallstone paitents (65.7% vs 18.5% , P <0.05). Conclusions Proportion of hepatolithiasis and gallstone was equal, and cholesterol stone was the main type in Hainan province. The incidence of hepatolithiasis and gallstone was related with voealion, living condition, dietany habit. Frequent biliary infection may play an important role in the formation of hepatolithiasis.

目的 探讨海南地区胆石病的临床流行病学特点及其影响因素。方法 对海南地区135例胆石病患者进行回顾性流行病学因素调查,对术中取得的胆石进行化学成份测定。 结果 胆管结石占51.9%,胆固醇类结石占65.9%。城镇居民、高脂饮食及肥胖者的胆囊结石发病率高,而农村居民、低脂饮食者的胆管结石发病率高。胆管结石患者的肌汁细菌培养阳性率(65.7%)高于胆囊结石患者的胆汁细菌培养阳性率(18.5%)。结论 海南地区胆石的分布部位胆囊结石与胆管结石比例接近;类型以胆固醇类结石为主。职业、生活条件、饮食习惯等因素与胆囊结石和胆管结石的发病率有关。高脂饮食及肥胖是造成胆囊结石的主要因素,而低营养、低脂饮食与胆管结石的形成有关。反复胆道细菌感染在胆管结石形成中可能起重要作用。

Objective To study the effects of calcitonin gene-related peptide( CGRP) and its antagonist of CGRP( h-CGRP 8-37) in normal and stress rats on bile reflux in stomach. Methods The study contained 85 SD rats and three parts. Part one:20 rats were randomly divided into control group and 10 μg/kg, 30 μg/kg, 50 μg/kg CGRP group. Peritoneal injection 30 min later,the bile acid in gastric juice was measured. Part two:The stress ulcer model was established by cold,water seaking. 35 rats were divided into 0 h(control...

Objective To study the effects of calcitonin gene-related peptide( CGRP) and its antagonist of CGRP( h-CGRP 8-37) in normal and stress rats on bile reflux in stomach. Methods The study contained 85 SD rats and three parts. Part one:20 rats were randomly divided into control group and 10 μg/kg, 30 μg/kg, 50 μg/kg CGRP group. Peritoneal injection 30 min later,the bile acid in gastric juice was measured. Part two:The stress ulcer model was established by cold,water seaking. 35 rats were divided into 0 h(control group) 2 h,4 h,6 h,8 h,10 h stress group and measured the gastric ulcer index and bile acid in gastric juice. The pyloric local CGRP was measured by a radioimmunoassay detection kit. Part three:30 rats were divided into stress group and h-CGRP 8-37 group. The gastric bile acid were measured after 2 h,4 h,6 h stress. Each hour group have 5 rats. Results The bile acid in CGRP group increased significantly compared with those of control group. The bile acid reached the maximum at 2 hours after finish stress. The ulcer index reached the maximum at 4 hours after finish stress. But the pyloric local CGRP decreased to the minimum at 4 hours after finish stress. And,the bile acid of h-CGRP 8-37 group was less than those of antagonist control group. Conclusion CGRP can promote bile add reflux in the stomach. CGRP affect and regulate the relaxation function of the pyloric sphincter.

目的探讨降钙素基因相关肽((CGRP)及其拮抗剂(h-CGRP 8-37)与正常和应激情况下大鼠胃内胆汁返流的关系。方法 SD大鼠85只,实验分三部分:第一部分大鼠20只随机分为四组:对照组和CGRP低、中、高剂量组各5只,分别腹腔注射生理盐水(1 ml)和CGRP(10 μg/kg 1ml)、CGRP(30μg/kg 1 ml)和CGRP(1 ml),0.5 h后处死,取胃液测胆汁酸(TBA)浓度。第二部分采用冷束缚应激法,将35只大鼠分为两组,对照组5只,实验组30只,从浸入水中开始取2、4、5、6、8、10 h共6个时段,每个时段各5只,分别检测其胃内胆汁酸的浓度和胃黏膜的溃疡指数(用Guth评分),用放免试剂盒检测幽门区CGRP含量。第三部分大鼠30只随机分为两组:应激组和h-CGRP 8-37组各15只,从浸入水中开始取2、4、6 h共3个时段,每个时段各5只。取胃液测TBA浓度。结果正常大鼠在腹腔注射不同剂量CGRP 0.5 h后胃内胆汁酸浓度明显增高;应激性溃疡大鼠于应激结束后2h(即从应激开始计时6 h)胃内胆汁酸达到峰值,溃疡指数和幽门区CGRP含量分别于应激结束后4 h达到峰值和降到波谷;...

目的探讨降钙素基因相关肽((CGRP)及其拮抗剂(h-CGRP 8-37)与正常和应激情况下大鼠胃内胆汁返流的关系。方法 SD大鼠85只,实验分三部分:第一部分大鼠20只随机分为四组:对照组和CGRP低、中、高剂量组各5只,分别腹腔注射生理盐水(1 ml)和CGRP(10 μg/kg 1ml)、CGRP(30μg/kg 1 ml)和CGRP(1 ml),0.5 h后处死,取胃液测胆汁酸(TBA)浓度。第二部分采用冷束缚应激法,将35只大鼠分为两组,对照组5只,实验组30只,从浸入水中开始取2、4、5、6、8、10 h共6个时段,每个时段各5只,分别检测其胃内胆汁酸的浓度和胃黏膜的溃疡指数(用Guth评分),用放免试剂盒检测幽门区CGRP含量。第三部分大鼠30只随机分为两组:应激组和h-CGRP 8-37组各15只,从浸入水中开始取2、4、6 h共3个时段,每个时段各5只。取胃液测TBA浓度。结果正常大鼠在腹腔注射不同剂量CGRP 0.5 h后胃内胆汁酸浓度明显增高;应激性溃疡大鼠于应激结束后2h(即从应激开始计时6 h)胃内胆汁酸达到峰值,溃疡指数和幽门区CGRP含量分别于应激结束后4 h达到峰值和降到波谷;经幽门局部给予CGRP拮抗剂能显著降低应激性溃疡大鼠胃内胆汁返流程度。结论 CGRP能促进胃内肌汁酸反流,CGRP参与了幽门括约肌舒张功能的调控。

 
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