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|  | | 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。 | |
From a biological point of view, it is surprising that the replication-competent genomes contained only an average of one artificial mutation.
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| | RCP-RFLPs is a fast,sensitive, economical and simple method to detect gene mutation,especially in the clinical study.In this research,we designed a pair of primers containing an artificially mutated point in order to use RCP-PFLPs.36 human rectal carcinomas,adjacent tissues and normal colon mucos were analyzed, and dicussed with the pathologic data.The result shows that the mutation rate of K-ras genes in cancerous tissues is significantly higher than that in normal or adjacent tissues(P<0.01).Three mutatio... | | PCR-RELPs法是一种快速灵敏、简单经济的基因突变检测手段,适于在临床上推广使用。K-RAS基因12位密码子是常见的突变热点,我们设计并合成一对在近3'-末端存在人为突变碱基的引物,对36例直肠癌手术切除标本、癌旁肉眼观察"正常"的粘膜组织标本及正常肠粘膜进行K-RAS基因扩增,并酶切分析12位密码子点突变,结果表明12位密码子突变所激活的K-RAS基因是伴随直肠癌的一种基因异常表现,是直肠癌的主要成因之一,并证明基因突变是癌变发生的早期行为。 | | 文摘来源 | |   |
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