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黑鼠
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     Effect of aging and sports loading on articular cartilage of C57 black mice—an histopathological study
     增龄及运动负荷对C57黑鼠关节软骨影响的组织病理学观察
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     Methods:By using RT PCR method,gene transcription of IL 1β,IL 6 and iNOS mRNA in the articular cartilage of the models of C57 black mice with osteoarthritis (OA) by sports loading was measured.
     方法 :以运动负荷造成 C5 7黑鼠 OA模型 ,以 RT- PCR方法测定各组动物关节软骨内 IL- 1β、IL- 6、i NOS m RNA基因转录水平。
短句来源
     Results:The gene expression of IL Iβ,iNOS increased distinctly in the articular cartilage of C57 black mice with OA,especially in the middle stage of OA.
     结果 :C5 7黑鼠关节软骨 IL- 1β、i NOS m RNA表达随增龄逐渐增强 ,OA中期最明显 ,晚期下降。
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     THE INFLUENCE OF TRADITIONAL CHINESE DRUGS ON SERUM SOD, HA AND NO LEVELS IN RATTUS RATTUS WITH KNEE OSTEOARTHRITIS
     中药对膝骨关节炎黑鼠血清SOD、HA、NO水平的影响
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     In a chronic experiment, young male C 57/BL mice were exposed to the inhalation of N-phenyl-2-naphthylamine aerosol in a specially devised cabinet;
     选用C_(57)黑鼠,在一特制的中毒橱中进行了PBNA气溶胶的吸入诱癌实验。
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     AFFERENT CONNECTIONS OF SUBSTANTIA NIGRA IN THE RAT
     大白质传入性联系
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     The Black Cat
    
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     Black Tulips
     郁金香
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     DIFFERENTIATION GRADIENT OF DOPAMINERGIC NEURONS IN SUBSTANTIA NIGRA OF RAT
     大白质多巴胺细胞化学分化的顺序(英文)
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     Immunogenicity of retina in mice
     视网膜的免疫原性
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  black rat
Using a Y-maze, we tested the hypothesis that female big brown bats (Eptesicus fuscus) avoid olfactory cues from known predators - raccoons (Procyon lotor) and black rat snakes (Elaphe obsoleta).
      
We found that big brown bats do not avoid cues from raccoon urine and there was a non-significant trend for bats to choose the arm with black rat snake cues.
      
In a second experiment, bats were exposed to olfactory and potentially auditory cues of live black rat snakes.
      
Three widely separated Malayan populations of Black rat, Rattus rattus diardii (Jentink), were found to comprise individuals with supernumerary (or B) chromosomes.
      
Banding pattern analysis of polymorphic karyotypes in the black rat by a new differential staining technique
      
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  house rat
Supernumerary (B-) chromosomes in the Malayan house rat, Rattus rattus diardii (Rodentia, Muridae)
      
The hair of the albino rat and the hair of the house rat are equal in length, but shorter than those of the wild norvegian rat.
      
The scales of the bristles are equal to those of the wild norvegian rat, the scales of the awns in the lower parts are equal to those of the house rat.
      
from the Malaysian house rat, Rattus rattus diardii
      
from the Malaysian house rat, Rattus rattus diardii, was studied with the electron microscope.
      
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In a chronic experiment, young male C 57/BL mice were exposed to the inhalation of N-phenyl-2-naphthylamine aerosol in a specially devised cabinet; atmospheric concentrations therein were 180—230 mg/m~3. Each mouse was exposed to the inhalation of aerosol 2 hours a day, 5 days a week for 1 year. All surviving experimental and control mice were sacrificed at the end of 22 months and subjected to detailed anatomical and histological examination. 50% (23/46) of 46 experimental mice developed various malignant tumors...

In a chronic experiment, young male C 57/BL mice were exposed to the inhalation of N-phenyl-2-naphthylamine aerosol in a specially devised cabinet; atmospheric concentrations therein were 180—230 mg/m~3. Each mouse was exposed to the inhalation of aerosol 2 hours a day, 5 days a week for 1 year. All surviving experimental and control mice were sacrificed at the end of 22 months and subjected to detailed anatomical and histological examination. 50% (23/46) of 46 experimental mice developed various malignant tumors with predominance of carcinoma of lungs (14/46). 47 untreated mice had 14.89% (7/47) malignant tumors without carcinoma of lung. Among the 14 lung cancers, 12 were adenocarcinomas.N-phenyl-2-naphthylamine is the main ingredient of a once widely used rubber antioxidant. The chemical tested in our experiment was 2-naphthylamine free as was shown by HPLC analysis. Therefore, the results demonstrated that very probably N-phenyl-2-naphthylamine itself is a carcinogen.

选用C_(57)黑鼠,在一特制的中毒橱中进行了PBNA气溶胶的吸入诱癌实验。中毒橱中PBNA的浓度为180—230毫克/立方米。动物每日吸入2小时,每周吸入5日,共吸入一年,饲养到22个月解剖。实验结果50%的实验动物(23/46)患了各种恶性肿瘤,其中肺癌14例。对照动物中14.89%患有恶性肿瘤(7/47),但无一例肺癌。实验组14例肺癌中12例为腺癌。PBNA是一种重要的橡胶配合剂,本实验用的PBNA经高压液相色层分析,证明不含2-萘胺,因此实验结果提示PBNA本身很可能是一个致癌物。

First we irradiated respectively RNA extracted from cancer cells with laser light at different wavelengths and energy then preheated the cancer cells RNA for 18 hrs and transplanted them into the absominal cavity of C_57 DL mice, and observed the influence of carcinoma growth. Result: Ⅰ3250A and 4416A group: no ascitic cancer for six months. Ⅱ.3371A group: ascitic cancer at some parts from the 21th day. Ⅲ.4880A~5145A-group: ascitic cancer caused in all mice from 50 th day, and a part engendered with abdominal...

First we irradiated respectively RNA extracted from cancer cells with laser light at different wavelengths and energy then preheated the cancer cells RNA for 18 hrs and transplanted them into the absominal cavity of C_57 DL mice, and observed the influence of carcinoma growth. Result: Ⅰ3250A and 4416A group: no ascitic cancer for six months. Ⅱ.3371A group: ascitic cancer at some parts from the 21th day. Ⅲ.4880A~5145A-group: ascitic cancer caused in all mice from 50 th day, and a part engendered with abdominal cavity consolidatic cancer.

从癌细胞提取的RNA,经3250A、4416A各8J,3371A6J及4880~5145A 9J分别照射,然后与定量癌细胞预温18小时,移植入C_(57)DL小黑鼠腹腔内,观察腹水癌形成与否的过程。实验结果:3250A及4416A组饲养6个月未发生腹水癌。3371A组从21天起部分形成腹水癌。4880~5145A组在50天内全部发生腹水癌,部分动物发生腹腔内实体癌。

Male C57 black mice showed moderately decreased hepatic glutathione (GSH) corteat 72 h after the injection of 1-methy1-4-pheny-1,2,3,6-tetrahydropyridine (MPTP), 35 mg/kg once a day for 7 days. In comparison with control, the levels of GSH in the hepatic mitochondria and microsomes were reduced by 28.1% and 32.4% respectively (p<0.01). Another group of mice received 3 injections of 35mg/kg at 4 intervals in a single day, exhibited slightly reduced GSH concentrations in the hepatic mitochondria, which were depleted...

Male C57 black mice showed moderately decreased hepatic glutathione (GSH) corteat 72 h after the injection of 1-methy1-4-pheny-1,2,3,6-tetrahydropyridine (MPTP), 35 mg/kg once a day for 7 days. In comparison with control, the levels of GSH in the hepatic mitochondria and microsomes were reduced by 28.1% and 32.4% respectively (p<0.01). Another group of mice received 3 injections of 35mg/kg at 4 intervals in a single day, exhibited slightly reduced GSH concentrations in the hepatic mitochondria, which were depleted by 21.3% compared with control (p<0.05). whereas GSH levels of hepatic microsomes were not affected. The result indicates that MPTP has dose-related effect of decreasing the hepatic GSH content of mice. It is suggested that our findings of low hepatic GSH concentrations in MPTP-treated mice may be due to excessive consumption of GSH in detoxification processes, or to MPTP-induced deficiency of GSH synthesis.

本文报道给雄性C_(57)小黑鼠腹腔注射两种剂量MPTP后,发现组2(MPTP35mg/kg每日1次7天)鼠肝线粒体和微粒体的谷胱甘肽(GSH)含量降低,比对照缉分别降低280.1%和32.4%(P<0.01)。组3(MPTP35mg/kg,4小时1次,共3次)鼠肝线粒体的GSH含量仅轻度下降,比对照组下降21.3%(P<0.05),微粒体的GSH含量则无改变。结果提示MPTP有降低鼠肝GSH含量的作用,并与其剂量有关。作用机理推测是由于GSH存清除MPTP诱致体内产生过量自由基的过程中自身过度耗竭,或是由于MPTP诱致GSH的合成障碍。

 
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