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腺泡腺癌
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     Prostate cancer with Gleason score of 8accounted for 25.3%(25/99)and 6.9%(8/115) in Changchunand Natori ,respectively. The differences werestatistically significant(P<0.01). Prostate cancer withGleason score of 6 accounted for 22.2%(22/99) and56.5%(65/115) in Changchun and Natori ,respectively.
     长春市人群中小腺泡腺癌所占比例为29.3%,名取市为73.9%(P<0.01)。
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  相似匹配句对
     Adenocarcinoma of the Esophagus
     食管腺癌
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     Primary esophageal adenocarcinoma
     原发性食管腺癌
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     The Expression or Inhibition of COX-2 in Pancreatic Cancer and Alcoholic Acinar Cells Retrogression
     环氧合酶-2与胰腺癌、酒精性胰腺腺泡细胞退行性变
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     (3) there was an increased incidence of adenocarcinoma, especially papillary adenocarcinoma and acinar adenocarcinoma and bronchioloalveolar carcinoma in the 1990s.
     (3)腺癌 ,特别是乳头状腺癌 ,腺泡样癌及细支气管肺泡癌增加。
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     (2) Alveolar node sign;
     (2)腺泡样结节;
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Objective To evaluate the differential diagnostic value of prostate specific antigen(PSA),P63,high molecular weight cytokeratin(CK34βE12)and P504S to prostate carcinoma(PA).Methods An immunohistochemical method for PSA,P63,CK34βE12 and P504S was modified as follows :(1) A reliably positive control tissue section was adhered beside the tested tissue section on the same slide;(2) The slide was treated with microwave oven to preserve and repair the antigens and(3) Developing the colour of sections must be controlled...

Objective To evaluate the differential diagnostic value of prostate specific antigen(PSA),P63,high molecular weight cytokeratin(CK34βE12)and P504S to prostate carcinoma(PA).Methods An immunohistochemical method for PSA,P63,CK34βE12 and P504S was modified as follows :(1) A reliably positive control tissue section was adhered beside the tested tissue section on the same slide;(2) The slide was treated with microwave oven to preserve and repair the antigens and(3) Developing the colour of sections must be controlled microscopically until the background was clear.Results The positive expression rates of PSA,CK34βE12,P63 and P504S 70.0%(14/20,80%((16/20),)66.3%(61/92),100.0%(20/20,80%((16/20),)5.4%(5/92),100.0%(20/20),90%(18/20,3.3%(3/92),and 10.0%(2/20),25%(5/20),85.7%(79/92)respectively.Positive rates of P63,CK34βE12 and P504S were significantly different(P<0.01) among three groups.Positive rates of P63 and CK34βE12 had close relation with Gleason histological grading of prostate carcinoma.PSA and CK34βE12 were not expressed in transitional cell carcinoma.Conclusion Modified immunohistochemistry and combined detection of PSA,P63,CK34βE12 and P504S can be most helpful for diagnosis and differential diagnosis of prostrates carcinoma.

目的探讨前列腺特异性抗原(PSA)、高分子量细胞角蛋白(CK34βE12)、P63和支链脂肪酸β氧化酶(P504S)改良免疫组化对前列腺癌鉴别诊断的作用。方法对92例前列腺癌(PA)、20例良性前列腺增生(BPH)和20例前列腺上皮内瘤(PIN)石蜡标本采用改良免疫组化染色法检查。即在同一侧贴附可靠的阳性对照组织,应用高压抗原修复法处理,尽可能保存和修复抗原,在显微镜下严格控制显色等方法以达到最佳染色效果并结合HE标本观察结果。结果PSA、CK34βE12、P63和P504S在BPH、PIN和PA中的阳性表达分别为70.0%(14/20)、80%(16/20)6、6.3%(61/92),100.0%(20/20)、80%(16/20)、5.4%(5/92),100.0%(20/20)、90%(18/20)、3.3%(3/92),10.0%(2/20)、25%(5/20)、85.7%(79/92)。3组间CK34βE12、P63和P504S阳性表达率有非常显著性差异(P<0.01)。CK34βE12和P63阳性表达与列腺腺泡腺癌的Gleason分级评分之间密切相关。膀胱尿路上皮癌PSA和CK34βE...

目的探讨前列腺特异性抗原(PSA)、高分子量细胞角蛋白(CK34βE12)、P63和支链脂肪酸β氧化酶(P504S)改良免疫组化对前列腺癌鉴别诊断的作用。方法对92例前列腺癌(PA)、20例良性前列腺增生(BPH)和20例前列腺上皮内瘤(PIN)石蜡标本采用改良免疫组化染色法检查。即在同一侧贴附可靠的阳性对照组织,应用高压抗原修复法处理,尽可能保存和修复抗原,在显微镜下严格控制显色等方法以达到最佳染色效果并结合HE标本观察结果。结果PSA、CK34βE12、P63和P504S在BPH、PIN和PA中的阳性表达分别为70.0%(14/20)、80%(16/20)6、6.3%(61/92),100.0%(20/20)、80%(16/20)、5.4%(5/92),100.0%(20/20)、90%(18/20)、3.3%(3/92),10.0%(2/20)、25%(5/20)、85.7%(79/92)。3组间CK34βE12、P63和P504S阳性表达率有非常显著性差异(P<0.01)。CK34βE12和P63阳性表达与列腺腺泡腺癌的Gleason分级评分之间密切相关。膀胱尿路上皮癌PSA和CK34βE12呈阴性表达。结论PSA、P63、P504S和CK34βE12改良的免疫组化法和抗体联合染色应用可作为前列腺癌诊断和鉴别诊断的重要指标。

 
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