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   ⅰ型前胶原 的翻译结果: 查询用时:1.263秒
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心血管系统疾病
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型前胶原     
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  procollagen ⅰ
     Results The TRH1 polypeptide could significantly inhibit the TGFβ1-induced collagen synthesis and down-regulate the expression of procollagen Ⅰ mRNA in the fibroblasts from keloids.
     结果 TRH1可以明显抑制TGF - β1所诱导的瘢痕疙瘩成纤维细胞的胶原合成及细胞Ⅰ型前胶原mRNA的表达。
短句来源
     procollagen Ⅰ mRNA in pulmonary arterioles and mPAP? MT%.
     ⑤肺细小动脉Ⅰ型胶原、Ⅰ型前胶原mRNA与mPAP、MT %均呈正相关。
短句来源
     The mRNAs of trans- forming growth factorβ_1(TGFβ_1)and procollagenⅠwere detected by reverse transcription-polymerase chain reaction(RT-PCR).
     应用逆转录-聚合酶链式反应(RT-PCR)检测胰腺组织转化生长因子β_1(TGFβ_1)、Ⅰ型前胶原mRNA表达;
短句来源
     The aqueous extracts of RPR reduced the expresstion of procollagen Ⅰ mRNA by 29 %, procollagen Ⅲ mRNA by 33 %.
     赤芍水提取物可以使Ⅰ型前胶原表达减少29%,Ⅲ型减少33%;
短句来源
     The serum content of procollagen Ⅰ(PCⅠ), procollagen Ⅲ(PCⅢ), laminin(LN) were measured by radioimmunoassay with all patients and 20 normal serum samples composing the control groups individually.
     放射免疫法测定心肌纤维化患者与健康对照组(20例)血清ECM[含Ⅰ型前胶原(PCⅠ)、Ⅲ型前胶原(PCⅢ)、黏连蛋白(LN)]含量,并与CVF、心功能作相关性分析。
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  procollagen type i
     Methods Procollagen type I (PCⅠ),procollagen type Ⅲ(PCⅢ),laminin(LN) and hyaluronic acid (HA) in serum were measured in 38 cases of myocardial infarction(MI group),32 cases of angina pectoris (AP group) and 34 normal aged people (NS group).
     方法 测定MI患者 38例 ,心绞痛 (AP)患者 32例及健康老年人 (对照组 ) 34名的血清Ⅰ型前胶原 (PCⅠ )、Ⅲ型前胶原 (PCⅢ )、层粘连蛋白 (LN)和透明质酸 (HA)水平。
短句来源
     Significance of increased serum procollagen type I carboxy terminal peptide in essential hypertension
     高血压病患者血清Ⅰ型前胶原羧基端肽水平升高的意义
短句来源
     The serum procollagen type I(PCI)of 76 healthy controls and 89 patients with various liver diseaseswere determined by radioimmunoassay.
     本文采用放免法检测了76例健康献血员、89例不同肝病患者血清Ⅰ型前胶原(PCI)的含量。
短句来源
     Relation of serum procollagen type I carboxy terminal peptide and left ventricular hypertrophy in essential hypertension
     高血压病患者血清Ⅰ型前胶原羧基端肽水平与左心室肥大的关系
短句来源
     METHODS: The right common carotid artery of male rabbits were injured with 3.5F balloon catheter. Four weeks after operation, arterial tissure collagen content, serum procollagen type I(PCI), procollagen type Ⅲ(PCⅢ) concentration, neointimal thickness and the rate of stenosis were measured.
     方法 :用家兔复制成颈总动脉内皮损伤模型 ,4周后检测血清中Ⅰ型前胶原 (PCI)、Ⅲ型前胶原 (PCⅢ )及动脉组织胶原含量 ,并行动脉组织病理形态学检查。
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  type i procollagen
     L~(-1) could obviously inhibit gene expression of type I procollagen(p<0.05), but the effect was not obvious at the concentration of 50g.
     L~(-1)浓度的茅台酒能明显抑制Ⅰ型前胶原基因表达(P<0.05),而50g.
短句来源
     Results Collagen synthesis and type I procollagen mRNA level in HS and normal dermal fibroblasts remained unchanged at energy level of 500J/cm 2,and were significantly decreased at energy densities of 1500 and 200J/cm 2(P<0.001).
     结果 肥厚性瘢痕与正常皮肤成纤维细胞胶原合成、Ⅰ型前胶原mRNA水平在 5 0 0J/cm2 照射后无变化 ,15 0 0J/cm2 、2 0 0 0J/cm2 照射后显著降低 (P <0 .0 0 1) ;
短句来源
     The serum concentrations of the carboxyterminal propeptide of type I procollagen (PICP) and aminoterminal propeptide of type Ⅲ precollagen (PⅢNP) on days 5, 15, 30 and 90 were determined by the radioimmunologic method.
     应用放射免疫法测定两组患者AMI后第 5、15、30、90天血清Ⅰ型前胶原羧基端肽 (PICP)和Ⅲ型前胶原氨基端肽 (PⅢNP)浓度。
短句来源
     Methods:Serum level of Osteocalcin (BGP), Calcitonin(CT), Parathyroid hormone(PTH), 25-hydroxyvitamin D(25-OH-D), Cross-linked carboxyterminal telopeptide of type I collagen (ICTP), Aminoterminal propeptide of type I procollagen (PINP) were measured by radioimmunoassay in 30 renal transplant recipients and 25 healthy people.
     方法:采用竞争性放射免疫分析法测定30例肾移植患者和25例健康献血者的血清骨代谢生化指标:骨钙素(BGP)、降钙素(CT)、甲状旁腺激素(PTH)和25羟基维生素D(25OHD)、Ⅰ型胶原羧基端交联肽原(ICTP)和Ⅰ型前胶原氨基端伸展肽(PINP)水平。
短句来源
     Objective To observe the changes of the serum concentrations of the carboxyterminal propeptide of type I procollagen (PⅠCP),aminoterminal propeptide of type Ⅲ precollagen (PⅢNP) and the left ventricle mass index (LVMI),and to evaluate the effects of spironolactone on myocardial collagen metabolism in patients with essential hypertension with left ventricle hypertrophy.
     目的观察在常规抗高血压治疗的基础上联合应用螺内酯对伴左心室肥厚的原发性高血压(EH)患者血清Ⅰ型前胶原羧基端肽(PⅠCP)、Ⅲ型前胶原氨基端肽(PⅢNP)和左心室质量指数(LVMI)的改变,了解螺内酯对EH患者心肌胶原纤维代谢的影响。
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  procollagen type ⅰ
     RT-PCR was performed to detect the expression of procollagen type Ⅰ mRNA.
     用RT-PCR方法检测Ⅰ型前胶原mRNA的表达。
短句来源
     The expression of procollagen typeⅠmRNA inⅠgroup was higher than that in control group(P<0.05).
     ②Ⅰ组肺组织Ⅰ型前胶原mRNA表达显著高于正常对照组和Ⅱ组(P均<0.05)。
短句来源
     Objective To investigate serum concentration of procollagen type Ⅰ carboxyterminal peptide (PⅠP), type Ⅲ aminoterminal peptide (PⅢP) and type Ⅰ collagen telopeptide (ICTP) in essential hypertension (EH).
     目的 测定高血压病 (EH)患者血清Ⅰ型前胶原羧基端肽 (PⅠP)、Ⅲ型前胶原氨基端肽 (PⅢP)和Ⅰ型胶原羧端交联肽 (ICTP)水平的改变 ,探讨其在高血压性心肌纤维化中的诊断价值。
短句来源
     (3)Expression of procollagen type Ⅰ mRNA in small and mid pulmonary arteries of the three groups:compared with rats in the control group,the expression increased by 49% and 68% respectively(P<0.01) for rats in the hypoxia group;
     (3)各组大鼠肺小型、中型肌性动脉中Ⅰ型前胶原mRNA表达的比较:低氧组较对照组分别增加49%、68%(P<0·01);
短句来源
     ObjectiveTo investigate the change of serum concentration of procollagen type Ⅰ carboxy-terminal peptide (PⅠCP) of patien ts with chronic Keshan disease.
     目的 探讨慢型克山病患者血清Ⅰ型前胶原羧基末端肽 (PⅠCP)浓度的变化。
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  procollagen type i
In the course of CVB3 myocarditis, CTGF upregulation coincided with increased cardiac TGF-β and procollagen type I mRNA expression, preceding the formation of fibrotic lesions.
      
The significantly enhanced transcript levels of TGF-β, CTGF, and procollagen type I in cultivated CVB3-infected primary cardiac fibroblasts substantiate the role of fibroblasts as a relevant cell population in cardiac remodeling processes.
      
Immunohistochemistry was performed using antibody of the amino-terminal end of the procollagen type I propeptide (M-57).
      
Serum concentration of procollagen type I carboxyterminal propeptide in systemic sclerosis
      
A 50% decrease in the amount of procollagen type I and type III mRNAs was observed after 2 and 4 days of coculture while collagenase gene expression was upregulated by 300% when compared with control lattices.
      
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  type i procollagen
Targeted inhibition of type I procollagen synthesis by antisense DNA oligonucleotides
      
Antisense DNA oligonucleotides directed against specific sequences within α1(I) and α2(I) mRNA of type I procollagen were complexed to a cell-specific carrier, and screened for their effectiveness in reducing α1(I) and α2(I) mRNA levels.
      
Osteocalcin, a biochemical marker for osteoblast activity, and the carboxy-terminal propeptide of type I procollagen (PICP), a marker of collagen formation, were slightly but not significantly higher in gastrectomy-treated patients.
      
Simultaneously, circulating carboxyterminal propeptide of type I procollagen (PICP) was released in the perfusion medium (threefold versus C).
      
Gene expression of type I procollagen was significantly greater in Group MH than in Group MC at 7?days postoperatively and was also significantly greater in Group AH than in Group AC at 28?days (P?>amp;lt;?0.05).
      
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