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阿尔茨海默型痴呆
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  “阿尔茨海默型痴呆”译为未确定词的双语例句
     Pathologic diagnosis of non-Alzheimer type dementia
     非阿尔茨海默型痴呆的病理诊断
短句来源
     The 9 year cognitive decline before dementia of the Alzheimer type: A prospective population-based study
     出现在阿尔茨海默型痴呆前9年的认知功能下降:一项基于人群的前瞻性研究
短句来源
     Results Among the 22 cases of neurodegenerative dementia, 12 cases were identified as non-Alzheimer type dementia, including Pick′s disease (2 cases), progressive supranuclear palsy (3 cases) and corticobasal degeneration (3 cases), dementia with Lewy bodies (1 case), and Parkinson′s disease (3 cases).
     结果  2 2例神经变性痴呆中 ,12例诊断为非阿尔茨海默型痴呆。 其中皮克病 2例 ,进行性核上性麻痹和皮质基底节变性各 3例 ,皮质型路易小体痴呆 1例 ,帕金森病合并痴呆 3例。
短句来源
     Clinical Study on Althemer's Disease Treatment by Adding or Substracting the Recipe of Dihuang Yinzi
     加减地黄饮子治疗阿尔茨海默型痴呆(AD)的临床研究
短句来源
     Medified and inventory of diagnostic clinical features for dementia of the Alzheimer’s type(DAT) develpoed by Cummings and Benson.
     修订Cummings和Benson设计的阿尔茨海默型痴呆诊断性临床特点调查表,用于阿尔茨海默氏病性痴呆和脑血管性痴呆。
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  相似匹配句对
     Pathologic diagnosis of non-Alzheimer type dementia
     非阿尔茨海默痴呆的病理诊断
短句来源
     Study on Symptom Progression in Senile Dementia of the Alzheimer Type with TCM
     中医对阿尔茨海默老年性痴呆病程之探讨
短句来源
     (3)D shape.
     D
短句来源
     (2)C shape;
     C ;
短句来源
     Discussion on Course of Alzemeimer's Dementia with Traditional Chinese Medicine
     中医对阿尔茨海默老年性痴呆病程之探讨
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  alzheimer type dementia
Extracellular amyloid deposits are a feature of both Alzheimer type dementia and the 'normal' aging process.
      
Psychiatric symptoms were investigated and compared in 95 patients with Alzheimer type dementia (DAT) and in 39 patients with Parkinson's disease with dementia (PD-D).
      
Antiamnestic effect of α7-nicotinic receptor agonist RJR-2403 in middle-aged ovariectomized rats with Alzheimer type dementia
      
Chronic treatment with RJR-2403 and 17β-estradiol had a pronounced antiamnestic effect under conditions of Alzheimer type dementia in middle-aged ovariectomized rats.
      
Post-mortem brain tissue was obtained from 28 patients with brain disorders, of which 15 had clinically diagnosed schizophrenia, 6 Alzheimer type dementia, 5 dementia with tangles and 2 cases of Down's syndrome.
      
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Medified and inventory of diagnostic clinical features for dementia of the Alzheimer’s type(DAT) develpoed by Cummings and Benson. In a study of dementia of Alzheimer’s(AD)and cerebral vascular disease (VD),the results showed that the DAT inventory correctly identified 100% of DAT and VD.This DAT inventory is considered simple and facility,and might be aid for clini cians to diagnose Alzheimer’s disease.

修订Cummings和Benson设计的阿尔茨海默型痴呆诊断性临床特点调查表,用于阿尔茨海默氏病性痴呆和脑血管性痴呆。结果表明此调查表可100%地诊断两种痴呆。认为此调查表简单易行,对临床工作者在诊断阿尔茨海默病时可能有助。

Objective To analyze the influence of elderly dementia living in urban and rural areas of Beijing on their survival rate. Methods The elderly people with dementia aged 60 years and over lived in Beijing was investigated since 1997 by two step method and the mortality of the same population was followed up in 2000. Results A total of 2 788 patients were collected in 1997, and 2 721 of them were visited in 2000. Sixty seven(2 4%) of them were lost for follow up due to making a move and other...

Objective To analyze the influence of elderly dementia living in urban and rural areas of Beijing on their survival rate. Methods The elderly people with dementia aged 60 years and over lived in Beijing was investigated since 1997 by two step method and the mortality of the same population was followed up in 2000. Results A total of 2 788 patients were collected in 1997, and 2 721 of them were visited in 2000. Sixty seven(2 4%) of them were lost for follow up due to making a move and other reasons. Among the followed 2 721 cases , 2 307 were still alive (82 7%) and 414 died (14 9%), with the annual fatality rate being 3 79%(standardized). For all 205 cases diagnosed as dementia in 1997, the accumulated fatality rate was 42 46%(standardized), being 5 folds of the fatality for the non dementia. No significant difference was found in the fatality rate between male and female dementia. The fatality of dementia in rural area and over 75 years of age increased. Age and living conditions influenced significantly the fatality, and the fatality rate increased in patients with dementia and dysfunction of body moving. Conclusions Dementia is a disease impacting seriously the survival of elderly people.

目的 观察老年期痴呆对老年人生存的影响。 方法  1997年采用 2阶段法对北京城乡 6 0岁及以上老年人群进行痴呆患病率调查 ,2 0 0 0年对该人群全面随访并进行 3年的死亡追踪。 结果  1997年基线调查共 2 788人 ,2 0 0 0年访到 2 72 1人 ,其中存活 2 30 7人 (82 7% ) ,死亡 4 14人(14 9% ) ,另因搬迁等失访 6 7人 (2 4 % ) ,以追踪到的 2 72 1例为纵向预后分析样本 ,年死亡率为3 79% (标化 )。 2 0 5例痴呆老年人 3年中死亡 10 1例 ,累计死亡率高达 4 2 4 6 % (标化 ) ,约为非痴呆患者的 5倍。在痴呆患者中性别间的死亡率差异无显著性 ,农村地区及 75岁以上高龄痴呆老人死亡率增加。但 75岁以下低龄痴呆患者及阿尔茨海默型痴呆对生存的影响更大 ,伴有躯体功能障碍的痴呆老人死亡率增加。 结论 痴呆是影响老年人生存及生活质量的重要疾病 ,应加强防治。

Objective:To evaluate cerebrospinal fluid (CSF) levels of total tau protein and amyloid beta peptide 1 42 (Aβ1 42) as biomarkers for the diagnosis of Alzheimer's disease (AD) and to determine whether age or severity of dementia influenced these levels. Methods: The samples were taken from 63 patients with probable or possible AD, 49 with Parkinson's disease (PD), 22 with dementia of none Alzheimer type (NAD), 10 with vascular dementia (VD), 11 with normal pressure hydrocephalus (NPH) and 24 with other neurological...

Objective:To evaluate cerebrospinal fluid (CSF) levels of total tau protein and amyloid beta peptide 1 42 (Aβ1 42) as biomarkers for the diagnosis of Alzheimer's disease (AD) and to determine whether age or severity of dementia influenced these levels. Methods: The samples were taken from 63 patients with probable or possible AD, 49 with Parkinson's disease (PD), 22 with dementia of none Alzheimer type (NAD), 10 with vascular dementia (VD), 11 with normal pressure hydrocephalus (NPH) and 24 with other neurological disorders without dementia (ND). The CSF levels of Aβ1 42 and tau protein were measured by sandwich ELISA, with duplicate samples of CSF. Results: Levels of CSF tau were significantly higher, and levels of Aβ1 42 were significantly lower in the AD group than in all other groups. The average levels of both tau and Aβ1 42 in CSF did not change obviously between groups of different age, nor among groups with different Minimental scale examination (MMSE) scores. Conclusion: Combined analysis of CSF levels of tau and Aβ1 42 was better than the assay of only CSF tau or Aβ1 42 level in discriminating AD from other types of dementia,neurodegenerative disorders and ND. Whether it is useful for the discrimination with mixed Alzheimer's disease remains unknown.

目的 :为探讨联合分析脑脊液中Tau蛋白和Aβ1 4 2含量作为生化指标对诊断阿尔茨海默病的意义 ,以及患者年龄、痴呆严重程度对脑脊液中Tau蛋白和Aβ1 4 2含量的影响。方法 :利用夹心酶联免疫法进行同份标本同时测定 ,分析了 6 3例阿尔茨海默病 (AD)患者与 4 9例帕金森病 (PD)、2 2例非阿尔茨海默型痴呆、10例血管性痴呆、11例正常颅压脑积水以及 2 4例非痴呆的神经科患者脑脊液中Tau蛋白和Aβ1 4 2的含量。 结果 :AD组脑脊液中Tau值 (pg mL)明显升高 (491.3± 379.9) ,Aβ1 4 2值 (pg mL)明显降低 (486 .1± 2 93.5 )。脑脊液中Tau值及Aβ1 4 2值与年龄或痴呆的严重程度MMSE得分值间无相关性。结论 :同时测定脑脊液中Tau和Aβ1 4 2含量较单独测定Tau值或Aβ1 4 2值对于AD的诊断具有良好的特异性。这一方法对于AD的诊断以及其他类型痴呆和不伴痴呆的其他神经系统疾病的鉴别诊断具有意义。但对于区别混合型痴呆的意义尚难确定。

 
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