myeloablative PBSCT group received cyclophosphamide (Cy) 120 mg/kg and single total body irradiation (STBI) 9~10 Gy or BU 16 mg/kg/melphalan(Mel)140~160 mg/m 2 plus Ara-c.
Pretreatment included consistent intravenous drip of cyclophosphamide in the dosage of 50 mg/kg for few days, ~(60)Co fractionated total body irradiation 5-6 Gy and total lymph nodes irradiation 6-8 GY.
Conclusions Fractional total body irradiation in 2 days with dose rate of 5 cGy/min, once per day, total dose of 7-12 Gy, the median lung absorbed dose under 7.5 Gy is a safe and effective pretreatment for hematopoietic stem cell transplantation.
Conclusion The results indicate that adaptive response of TCR +,CD3 +,CD4 +CD8 +,CD4 +CD8 - and CD4 -CD8 + subsets of thymocytes can be induced by whole body irradiation with 0.075 Gy X rays.
Conclusion: The results mentioned above indicate that when the mice were irradiated with 75 mGy (D_1, 12.5 mGy/min ) 3~12 hours before 1.5 Gy (D_2, 0.285 Gy/min) exposure, the adaptive response of apoptosis and cell cycle progression may be induced with the thymocytes cultured for 4 and 20 hours after whole-body irradiation with D_2. 〔
Methods: In the experiment the medel of Kunming male mice with whole-body irradiation (WBI) was used. The inductive dose(D1) was 75 mGy and the challenge dose (D2) was 1.5 or 2.0 Gy. The interval time between D1 and D2 was 6h.
Lewis lung carcinoma or B_(16)melanoma cells were injected into the retrobulbar vein of mice 24h after whole-body irradiation (WBI) with 50, 75 , 100 or 150 mGy X-rays.
The morphological changes of Auerbach's ganglions in the duodenums of 12 rats were investigated 24,48 and 72 hours after whole-body irradiation by 25 Gy ~(60)Co γ-ray.
myeloablative PBSCT group received cyclophosphamide (Cy) 120 mg/kg and single total body irradiation (STBI) 9~10 Gy or BU 16 mg/kg/melphalan(Mel)140~160 mg/m 2 plus Ara-c.
Bone marrow aplasia was induced by fractionated whole body irradiation with 3000 R and restitution was started by autologous bone marrow transplantation.
Considerable insight has been gained in electromagnetic induced heat deposition patterns for the case of whole body irradiation and for local irradiations which can cause hot spot type of heating patterns.
Neutropenia was induced by 600 rad whole-body irradiation; an infection was induced by the injection of 5 × 106Escherichia coli into the thigh on Day 5 after irradiation.
Therefore, effects from low dose (1.0 R) whole-body irradiation would appear to include a recurrent defect in the expression of the net negative surface charge.