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性溃疡
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     Results: The children with duodenal ulcer (DU) accounted for 84.8%(39/46); gastric ulcer (GU),13%(6/46); complex ulcer, 2.2% (1/46).
     结果 :十二指肠溃疡 (DU)占 84.8% (39/ 46 ) ,胃溃疡 (GU)占 13 % (6 / 46 ) ,复合性溃疡占 2 .2 % (1/ 46 ) ;
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     Among them,48.22% (2 097cases) were of duodenal ulcer,44.18% (1 921 cases) of gastric ulcer, and the rest 7.59% (330 cases) of complex ulcer.
     结果在所有被检查患者中检出消化性溃疡 4 348例( 15.23%),其中十二指肠溃疡 2 097例( 48.22%),胃溃疡 1 921例( 44.18%),复合性溃疡 330例( 7.59%)。
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     The detection rates of H.pylori in patients with chronic gastritis(CG), peptic ulcer(PU) gastric ulcer(GU), duodenal ulcer(DU),compound ulcer(COU)were 66.1%(121/183),82.0%(109/133), 74.2%(23/31), 84.7%(72/85) and 82.4% (14/17) respectively.
     消化性溃疡的感染率为82.0%(109/133), 其中胃溃疡的感染率为74.2%(23/31),十二指肠溃疡感染率为84.7%(72/85),复合性溃疡感染率为82.4%(14/17)。
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     Long-term complications included epigastric pain and sour regurgitation in 16 cases(7.8%), enterolysis in 4(1.9%), duodenal bulb allaxis in 39(18.2%), chronic gastritis in 21(10.3%), and recurrent ulcer in 6(2.9%).
     术后远期并发症有:偶尔上腹痛、返酸16例(7·8%),粘连性肠梗阻4例(1·9%),十二指肠球变型39例(18·2%),慢性胃炎21例(10·3%),复发性溃疡6例(2·9%)。
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     Results In all endoscopic cases,2298 cases of peptic ulcer were found,the detecting rate was 14.52%. Among them,58.98%(1376 cases) were of duodenal ulcer,32.16%(739 cases) were of gastric ulcer,7.96%(183 cases) were of complex ulcer.
     结果消化性溃疡检出2298例,检出率14.52%,其中十二指肠溃疡(DU)1376例(59.88%),胃溃疡(GU)739例(32.16%),复合性溃疡(CU)183例(7.96%)。
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     Complications of Ulcerative Colitis
     溃疡结肠炎的并发症
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     ⑦callour perforated ulcer;
     ⑦胼胝溃疡穿孔;
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In this article three patients with gastrinoma were reported. Clinically, those patients have shown abdominal pain, diarrhea, melena, racnrrent ulcer and association with other endocrine diseases. The symptomatology of this condition often resembles that of ordinary peptic ulcer. The diagnosis is made on the basis of clinical manifestations, radiologic findings, gastric anaylsis and serum gastrin measnrmerit. On the other hand, whenever a patient with severe intractable ulcer, marginal ulcer, peptic ulcer associated...

In this article three patients with gastrinoma were reported. Clinically, those patients have shown abdominal pain, diarrhea, melena, racnrrent ulcer and association with other endocrine diseases. The symptomatology of this condition often resembles that of ordinary peptic ulcer. The diagnosis is made on the basis of clinical manifestations, radiologic findings, gastric anaylsis and serum gastrin measnrmerit. On the other hand, whenever a patient with severe intractable ulcer, marginal ulcer, peptic ulcer associated with diarrhea and/or other endocrine abnomalities, the possibility of gastrinoma should be seriously considered.

本文报告胃泌素瘤3例,其临床表现为腹痛、腹泻、黑便、胃次全切除术后复发性溃疡或并发其他内分泌异常等,常与普通溃疡病相似。诊断主要依靠临床表现,胃肠X线检查,胃液分析与测定血清胃泌素等,若遇严重、顽固性溃疡病,边缘溃疡,溃疡并发腹泻或内分泌疾患应高度警惕本病。并结合文献讨论此病的手术治疗问题。

Radioimmunoassay of serum gastrin was performed with 430 blood samples in different subjects. The fasting serum gastrin level obtained from 34 healthy people was 57±38 pg/ml, and showed no significant difference in sex distribution.Of the fasting serum gastrin level determined in patients with 15 kinds of various diseases, hypergastrinemia occurred in gastrinoma (one case, 700 pg/ml), diabetes mellitus (95 pg±16 pg/ml), hyperthyroidism (109±21 pg/ml) and uremia (171±41 pg/ml), and hypogastrinemia appeared in...

Radioimmunoassay of serum gastrin was performed with 430 blood samples in different subjects. The fasting serum gastrin level obtained from 34 healthy people was 57±38 pg/ml, and showed no significant difference in sex distribution.Of the fasting serum gastrin level determined in patients with 15 kinds of various diseases, hypergastrinemia occurred in gastrinoma (one case, 700 pg/ml), diabetes mellitus (95 pg±16 pg/ml), hyperthyroidism (109±21 pg/ml) and uremia (171±41 pg/ml), and hypogastrinemia appeared in hypothyroidism (21±7 pg/ml). The fasting serum gastrin level was within normal limits in patients with the rest of diseases, such as peptic ulcer, chronic gastritis, subtotal gastrectomy, gastric cancer, liver cirrhosis, hypercorticalismus and hepatoma.Both hyperthyroidism and hypothyroidism showed no correlation between fasting serum gastrin level and serum T_3(or T_4) level, and their coefficient of correlation was 0.17 and 0.16 respectively.Except gastrinoma, both basal gastric acid secretion and peak gastric acid secretion after administration of maximal histamine were adversely related to the fasting serum gastrin level, namely, the higher the gastric acid level, the lower the gastrin level, and vice versa.After renal dialysis, the fasting serum gastrin level in patients with uremia decreased in the majority of patients, but there was no significant difference in comparison with the two groups before and after the dialysis.Fasting serum gastrin level always increased following gastroscopy, and the increment lasted for about two hours.There was no influence on fasting serum gastrin level at 30 minutes and 60 after administration of maximum histamine.The calcium provocative test was performed in order to increase the diagnostic effectivity in gastrinoma.We performed the preliminary observation on the G-cell in the gastric antrum.

用放射免疫法测定血清胃泌素430例次。34例正常人空腹血清胃泌素为57±38pg/ml,男女无差别。为15种病患者测血清基础胃泌素含量,增高者有胃泌素瘤(1例,700pg/ml)、糖尿病(95±16pg/ml)、甲状腺机能亢进症(109±21pg/ml)、尿毒症(171±41pg/ml),减低者有甲状腺机能低下(21±7pg/ml)。其它如消化性溃疡、慢性胃炎、胃次全切除术后、胃癌、肝硬化、肾上腺皮质机能亢进、肝癌等均在正常范围。甲状腺机能亢进和机能低下患者,血清中的T_3或T_4含量,与其血清基础胃泌素含量的相关系数r分别为0.17和0.16,均不相关(P>0.05)。除胃泌素瘤外,胃酸(无论基础胃酸或最大组织胺后的高峰胃酸)与血清基础胃泌素含量间呈相反的关系,即胃酸愈高,胃泌素愈低,反之亦然。尿毒症经肾透析后,血清胃泌素多能下降,但将透析前后分别作为二组来比较,则无显著差异。胃镜检查后血清胃泌素显著上升,持续2小时方恢复正常。最大组织胺试验后30和60分钟时,对血清胃泌素含量无影响。开展钙兴奋试验,以提高对胃泌素瘤的诊断效率。对胃窦的G细胞进行了初步观察。

This paper reports 520 cases hospitalized due to upper gastrointestinal tract hemorrhage during a period of 12 years. The most common causes were: peptic ulcer, portal hypertension, gastritis and stomach cancer. Usually the degree of bleeding in peptic ulcer was mild; massive hemorrhage was more often in portal hypertension, which might be correlated to liver failure in blood coagulation disorder, yielding a fatality of 39.1%. Acute and chronic superficial gastritis might be the cause of bleeding among gastritis....

This paper reports 520 cases hospitalized due to upper gastrointestinal tract hemorrhage during a period of 12 years. The most common causes were: peptic ulcer, portal hypertension, gastritis and stomach cancer. Usually the degree of bleeding in peptic ulcer was mild; massive hemorrhage was more often in portal hypertension, which might be correlated to liver failure in blood coagulation disorder, yielding a fatality of 39.1%. Acute and chronic superficial gastritis might be the cause of bleeding among gastritis. Malignant tumor as an unusual source of hemorrhage was more frequent than its benign counterpart. In general, though the causes of upper gastrointestinal tract hemorrhage are various in type, a careful history and examinations including endoscopic and radiologic studies may give a definite diagnosis.

本院在过去的12年内共收治上消化道出血520例,引起出血的最常见疾病是消化性溃疡和门脉高压,其次是胃炎和胃癌.溃疡病的出血多不严重,难以控制的致命性大出血比较少见.肝硬化门静脉高压的出血常是大量的急性出血,病死率高达39.1%,这可能与出血量多及肝功能衰竭等因素有关.最易导致出血的胃炎为急性出血性胃炎和慢性浅表性胃炎.在上消化道肿瘤中恶性较良性的易于发生出血.总之,上消化道出血的原因是多种多样的,只要进行认真的检查,一般都可以作出明确诊断.

 
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