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  elderly patients
The early percutaneous coronary intervention in elderly patients with acute coronary syndrome
      
It was shown that early PCI might be an effective and safe method to treat elderly patients with ACS.
      
Correlations between the impairments of higher cortical functions (assessed by clinical scores and neuropsychological tests) and multichannel EEG spectra were analyzed in elderly patients with mild dementia and children with cognitive problems.
      
Thus, the 5-HTT gene polymorphisms do not affect the risk of depression but is possibly associated with specific clinical signs of the disease, at least in elderly patients.
      
The risk factors for RCIN are primarily pre-existing (even mild) renal dysfunction, diabetes mellitus, absolute or relative hypovolemia, nephrotoxic drugs, etc., particularly in elderly patients.
      
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To explore the efficacy and security of intravenous thrombolytic therapy in patients of different ages,the urokinase(UK) was intravenously used to 113 patients with acute myocardiac infarction (AMI) onsetting with in 24 hours.The dosage was ranged for 1 to 1.5 million units and it was mixed with 100 ml normal saline in 30 min for intravenous drip.The patients were divided into four groups according to their ages:<49,50~59,60~69 and >70.The results were as follows:①when UK was given within 6 hours after AMI onset,the...

To explore the efficacy and security of intravenous thrombolytic therapy in patients of different ages,the urokinase(UK) was intravenously used to 113 patients with acute myocardiac infarction (AMI) onsetting with in 24 hours.The dosage was ranged for 1 to 1.5 million units and it was mixed with 100 ml normal saline in 30 min for intravenous drip.The patients were divided into four groups according to their ages:<49,50~59,60~69 and >70.The results were as follows:①when UK was given within 6 hours after AMI onset,the differences of the repatency rate,complications such as bleeding and death rate within 5 weeks were not significant (P>0.05) among these groups;②when UK was given at 7~12 hours after AMI onset,the repatency rates of the groups under 69 years were near each other (P>0.05);③when UK was given at over 12 hours after AMI onset ,there were no repatency in all treated groups.The facts indicate that the key to improve the efficacy of the thromblytic therapy is time.The earlier,the better.Ages should not be restrictive factor for thrombolytic therapy.

为了探讨不同年龄急性心肌梗塞患者静脉溶栓治疗的有效性及安全性,本试验对113例起病在24h内的患者行尿激酶静脉溶栓治疗,剂量100~150万U加生理盐水100ml30min内静滴。分<49岁,50~59岁,60~69岁,≥70岁4个年龄组进行分析比较。结果各年龄组6h内再通率,出血等并发症及5周病死率无显著性差异(P>0.5);7~12h再通率前3组无显著差异(P>0.5),≥70岁组无再通;>12h各年龄组均无再通。表明提高溶栓疗效关键是争取时间,认为年龄不应作为限制溶栓的条件,只要时间把握好,无禁忌证,>70岁高龄患者仍要积极溶栓,其利大于弊。

The 20 years data from 2 792 cases of acute myocardial infarction (AMI) were divided into 4 groups in every five years, and the morbidity, mortality and prognosis were compared. The results showed, during the last 15 years, the total case numbers admitted to hospital were increased gradually for every fiveyear period. During the recent 10 years, the aged cases increased significantly, and the case number complicated with heart failure rose up and that with arrhythmias went down obviously. For constitute ratio...

The 20 years data from 2 792 cases of acute myocardial infarction (AMI) were divided into 4 groups in every five years, and the morbidity, mortality and prognosis were compared. The results showed, during the last 15 years, the total case numbers admitted to hospital were increased gradually for every fiveyear period. During the recent 10 years, the aged cases increased significantly, and the case number complicated with heart failure rose up and that with arrhythmias went down obviously. For constitute ratio of death, there was a trend that aged cases and reinfarction increased steadily. Most deaths resulted from heart failure,ventricular fibrillation or cardiac shock, the main death cause was heart failure especially for aged AMI. Therefor, It is the key measure for AMI cases to be hospitalized to prevent from heart failure. 

将我院近20年的2792例急性心肌梗塞(AMI)患者的资料,按不同时期分为4组进行比较。结果表明,近15年来,AMI住院总数呈现每5年递增趋势,进入90年代后高龄患者明显增多,合并症中心衰增多,心律失常大大减少。病死构成比显示,近10年来高龄组及再发梗塞患者有所增加。总死因的前3位分别为心衰、室颤并心衰和(或)休克以及心衰并休克;高龄组主要死因为心衰。因此在AMI患者住院期间积极预防和控制泵衰竭是减少病死率的关键。

Objective To investigate the effectiveness of defferent emergency measures for acute myocardial infarction.Methods 126 cases of acute myocardial infarction were divided into non thrombolytic therapy group ( n =37), thrombolytic therapy group in 6 h ( n =49) and thrombolytic therapy group after 6 h ( n =40). Coronary reopen, heart event and complications were compared among the three groups after treatment.Results There was significant difference in the coronary reopen, heart event and omplications...

Objective To investigate the effectiveness of defferent emergency measures for acute myocardial infarction.Methods 126 cases of acute myocardial infarction were divided into non thrombolytic therapy group ( n =37), thrombolytic therapy group in 6 h ( n =49) and thrombolytic therapy group after 6 h ( n =40). Coronary reopen, heart event and complications were compared among the three groups after treatment.Results There was significant difference in the coronary reopen, heart event and omplications between thrombolytic therapy group and non thrombolytic therapy group ( P < 0.01 , P < 0.05 ). There was significant difference in the coronary reopen between thrombolytic therapy group in 6 h and thrombolytic therapy group after 6 h ( P < 0.05 ).Conclusion The effectiveness of early thrombolytic therapy for acute myocardial infarction was satisfactory. Time window of throbmolytic therapy does not limit in 6 h. Some patients who have better physical state and can adapt to thrombolytic therapy should take active thrombolytic therapies as the principle.

目的 采取不同的急救措施 ,探索心肌梗死的治疗效果。方法 将 12 6例患者分成非溶栓治疗组 (37例 )、6h以内溶栓治疗组 (49例 )、6h以后溶栓治疗组 (40例 )。治疗后进行各组冠状动脉再通、心脏事件和并发症的比较。结果 溶栓治疗和非溶栓治疗组 ,冠状动脉再通、心脏事件及并发症的比较P <0 .0 1、P <0 .0 5。 6h以内溶栓治疗组和 6h以后溶栓治疗组 ,冠状动脉再通、心脏事件及并发症的比较P <0 .0 5、P >0 .0 5。结论 急性心肌梗死早期采取溶栓治疗效果比较理想 ,而溶栓治疗的时间窗并不一定限制在 6h以内。对身体状况好 ,又适应溶栓治疗的患者 ,仍以积极溶栓治疗为原则 ,但高龄患者溶栓治疗应持谨慎态度

 
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