Methods:Female pregnant CBA/J mice in experimental group received an intraperitoneal (i.p) injection of 100μg of anti-mouse CD86 mAb in 200μl of PBS at d 4.5 of gestation,and the irrelevant-isotope matched rat IgG2b was administrated in control group with the same dosage and at same time.
Methods A prospective case-control study was performed in 59 women with abnormal gestational glucose tolerance(31 GDM and 29 GIGT) and 110 cases of normal oral glucose tolerance test(OGTT) as control recruited from Jun 2005 to Des 2005 in Taiyuan Maternal and Infant Health Care Hospital.
An increased allantoin level in the trophoblast and serum of pregnant women has been demonstrated.
Blood of healthy male and female volunteers lacked catalytically active antibodies, whereas antibodies from blood of pregnant women hydrolyzed DNA and RNA and their relative activity varied over a wide range.
The DNase activity of IgG and IgM from blood of healthy pregnant women was 4-5 times less than that from pregnant women with pronounced autoimmune thyroiditis.
Changes in osmolality and the concentration of cations (Na, K, Ca, Mg) were studied in blood serum of pregnant women from two weeks after conception, throughout the whole pregnancy, and within the first week after delivery.
Clinical and EEG spectral analysis was carried out in 14 pregnant women (five women at risk of preterm labor and four with miscarriage).
AFP expression appears in fetal hepatocytes at four weeks' gestation.
It peaks at 16-24 weeks' gestation and decreases gradually afterwards.
Fetal hepatocytes at 4-16 weeks' gestation are mainly constituted by HSCs characterized with bi-potential differentiation capacity.
At 16 weeks' gestation, most hepatic cord cells begin to differentiate into hepatocytes and abundant HSCs remain in ductal plate (the origin site of Hering canals).
The survival rate, physical development, and spontaneous behavior has been evaluated in pups of albino rats exposed to acute hypobaric hypoxia on the 9-10th day of gestation corresponding to the onset of organogenesis.