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妊娠
相关语句
  pregnancy
    A Fluorospectrophotometric Determination of Rivanol in Plasma for Inducing Abortion in Middle Pregnancy
    体液中药物测定方法的研究 Ⅰ.中期妊娠引产药利凡诺的荧光分光光度法
短句来源
    SERUM THYROXINE-BINDING GLOBULIN DURING PREGNANCY AND ITS RELATION BETWEEN URINARY ESTRIOL AND SERUM THYROXINE
    妊娠期血清甲状腺素结合球蛋白及其与甲状腺素和尿雌三醇的关系
短句来源
    [Objective] To evaluate whether the combination of an antiprogestin (mifepristone)+aromatase inhibitors (letrozole or aminoglutethimide) or an iNOS inhibitor (aminoguandine) are effective in ending pregnancy during early gestation in rhesus monkeys.
    [目的]评价抗黄体酮(mifepristone)联合Aromatase抑制剂(letrozole或aminoglutethimide)或iNOS抑制剂(aminoguandine)是否能有效终止恒河猴早期妊娠
    QSAR STUDY ABOUT PREGNANCY\|TERMINATING ACTIVITY OF 3,5-DIARYL\|s\|TRIAZOLES
    3,5-二芳基-s-三氮唑类化合物终止妊娠活性的QSAR研究
短句来源
    Effects of mifepristone on ultrastructure of placental Hofbauer cells in early human pregnancy
    米非司酮对妊娠早期人绒毛Hofbauer细胞超微结构的影响
短句来源
更多       
  pregnant
    INFLUENCES OF 15-METHYL-PROSTAGLANDIN F_(2α)AND 13-DEHYDRO-ω-EIHYL-PROSTAGLANDIN F_(2α)ON PLASMA PROGESTERONE OF PREGNANT RATS
    15甲基前列腺素 F_(2α)和13去氢ω—乙基前列腺素 F_(2α)对妊娠大鼠血中孕酮的影响
短句来源
    TERATOGENESIS OF 2-N, N-BIS (HRDROXYMETHYL) AMINO -1,3, 4-THIADIAZOLE (BIS-HM-A-TDA) ON PREGNANT RATS AND DETOXICATION OF NICOTINAMIDE (NA) AS WELL AS NICOTINIC ACID (NiA)
    2-N,N-双(羟甲基)氨基-1,3,4噻二唑对妊娠大白鼠的致畸和菸酰胺及菸酸的解毒作用
短句来源
    TERATOGENIC EFFECTS OF ROUTES OFDIFFERENT ADMINISTRATION OF 2-N, N-BIS (HYDROXYMETHYL)AMINO-1, 3, 4-THIADIAZOLE (BIS-HM-A-TDA)ON PREGNANT RATS AND DETOXICATION OF NICOTINAMIDE (NA) AND NICOTINIC ACID (NIA)
    2-N.N-双(羟甲基氨基)-1.3.4-噻二唑不同给药途径处理对妊娠大白鼠的致畸效应及菸酰胺和菸酸的解毒作用
短句来源
    Effect of RU486 on Glycoprotein in Pregnant Tissue
    RU486对人妊娠组织糖蛋白影响的研究
短句来源
    STUDY ON ANTAGONISM OF TRACE ELEMENT ON Cd-INDUCED DAMAGE OF PREGNANT RAT'S HEPATIC CELLS──Ⅰ. PROTECTIVE ACTION OF VARIOUS DOSES COMPOUND ZINC PREPARATION ON LIVER FROM Cd-INDUCED DAMAGE
    锌、硒拮抗镉致妊娠大鼠肝细胞损伤的研究──Ⅰ.不同剂量的复方锌对镉致妊娠大鼠肝细胞损伤的保护作用
短句来源
更多       
  preg nancy
    A Fluorospectrophotometric Determination of Rivanol in Plasma for Inducing Abortion in Middle Pregnancy
    体液中药物测定方法的研究 Ⅰ.中期妊娠引产药利凡诺的荧光分光光度法
短句来源
    SERUM THYROXINE-BINDING GLOBULIN DURING PREGNANCY AND ITS RELATION BETWEEN URINARY ESTRIOL AND SERUM THYROXINE
    妊娠期血清甲状腺素结合球蛋白及其与甲状腺素和尿雌三醇的关系
短句来源
    [Objective] To evaluate whether the combination of an antiprogestin (mifepristone)+aromatase inhibitors (letrozole or aminoglutethimide) or an iNOS inhibitor (aminoguandine) are effective in ending pregnancy during early gestation in rhesus monkeys.
    [目的]评价抗黄体酮(mifepristone)联合Aromatase抑制剂(letrozole或aminoglutethimide)或iNOS抑制剂(aminoguandine)是否能有效终止恒河猴早期妊娠
    QSAR STUDY ABOUT PREGNANCY\|TERMINATING ACTIVITY OF 3,5-DIARYL\|s\|TRIAZOLES
    3,5-二芳基-s-三氮唑类化合物终止妊娠活性的QSAR研究
短句来源
    Effects of mifepristone on ultrastructure of placental Hofbauer cells in early human pregnancy
    米非司酮对妊娠早期人绒毛Hofbauer细胞超微结构的影响
短句来源
更多       
  “妊娠”译为未确定词的双语例句
    TERAT03ENIC EFFECTS OF BDILEQ DJ-KU-SHUANG [N. N-Methylena-bis (2-amino-1,3,4 -thiadiazole) | DISTILLED WATER SOLUTION ON THE PREGENANT RATS
    敌枯双[N,N’-甲撑-双-(2-氨基-1,3,4-噻二唑)]煮沸水溶液对妊娠大白鼠的催畸效应
短句来源
    THE DETERMINATION OF TERATOGENIC SUSCETIBLE PERIOD OF RAT TO MICROWAVE RAEIATION
    微波辐射对妊娠大白鼠致畸敏感期的测定
短句来源
    CLINICAL STUDY ON THERAPEUTIC ABORION BY PGE_2 AND PGE_1 OF 513 SUBJECTS
    前列腺素E_2和E_1治疗性中期妊娠引产513例的临床观察
短句来源
    Placental Transfer and Pharmacokinetics of Cefotaxime in Pergnant Rats
    头孢氨噻肟在妊娠大鼠的胎盘转运
短句来源
    Maternal Toxicity in Rats Induced by Exposure to Methylmercury DuringPregnancy
    妊娠期甲基汞暴露对大鼠的母体毒性
短句来源
更多       
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  pregnancy
Reverse transcription-polymerase chain reaction (RT-PCR) was undertaken to examine the concentration of HGF mRNA and Fas mRNA obtained from 34 cases of HDCP and 30 cases of uncomplicated pregnancy.
      
Morphofunctional State of Epiphysis in Relatively Wild and Domesticated Silver-Black Foxes during Pregnancy
      
Morphological indices of changes in the epiphysis activity during pregnancy are analyzed in relatively wild and domesticated silver-black foxes.
      
The diameter of light actively functioning nuclei of pinealocytes increased most significantly and reliably in the end of pregnancy and, at the same time, the area of their surface decreased.
      
Unlike other stages of ontogenesis, the degree and dynamics of epiphysis activity during the period of pregnancy were similar in animals of both groups.
      
更多          
  pregnant
An increased allantoin level in the trophoblast and serum of pregnant women has been demonstrated.
      
Blood of healthy male and female volunteers lacked catalytically active antibodies, whereas antibodies from blood of pregnant women hydrolyzed DNA and RNA and their relative activity varied over a wide range.
      
The DNase activity of IgG and IgM from blood of healthy pregnant women was 4-5 times less than that from pregnant women with pronounced autoimmune thyroiditis.
      
Changes in osmolality and the concentration of cations (Na, K, Ca, Mg) were studied in blood serum of pregnant women from two weeks after conception, throughout the whole pregnancy, and within the first week after delivery.
      
Clinical and EEG spectral analysis was carried out in 14 pregnant women (five women at risk of preterm labor and four with miscarriage).
      
更多          
  preg nancy
Addi tional eld trials are needed verify the preg nancy and live birth rates of IVF-derived em bryos produced from this new sexed semen.
      
A forty-eight years old female, with previous lose of preg nancy in the first trimester and superficial venous thrombosis of lower left limb.
      
A healthy lifestyle and folic acid sup plementation is recommended before attempting another preg nancy.
      
An electron micrograph of the apical portion of a uterine luminal epithelial cell on Day 5 of preg nancy.
      
As the preg nancy continues, the mercury levels in umbilical cord blood will eventually surpass their levels in the mother's blood.
      
更多          


The influences of 15-methyl-prostaglandin F_(2α)(15-methyl-PGF_(2α))and 13-dehydro-ω-ethyl-prostaglandin F_(2α)(13-dehydro-ω-ethyl-PGF_(2α))on plasma pro-gesterone(P)and their effects on the termination of early pregnancy were studiedin pregnant rats by the same doses of 0.5mg/rat i.m.b.i.d on Day 7 of gestation.Theplasma Plevels at 4,8,24 hours after 15-methyl-PGF_(2α)were lowered down to 56.6%,43.7% and 13.3% of the initial values respectively.Pregnancy was terminated72 hours after 15-methyl-PGF(2α)administration...

The influences of 15-methyl-prostaglandin F_(2α)(15-methyl-PGF_(2α))and 13-dehydro-ω-ethyl-prostaglandin F_(2α)(13-dehydro-ω-ethyl-PGF_(2α))on plasma pro-gesterone(P)and their effects on the termination of early pregnancy were studiedin pregnant rats by the same doses of 0.5mg/rat i.m.b.i.d on Day 7 of gestation.Theplasma Plevels at 4,8,24 hours after 15-methyl-PGF_(2α)were lowered down to 56.6%,43.7% and 13.3% of the initial values respectively.Pregnancy was terminated72 hours after 15-methyl-PGF(2α)administration in all the rats of this group.Theplasma P levels at 4,8,24 hours after 13-dehydro-ω-ethyl-PGF_(2α)were reducedto 63.5%,34.4% and 51.9% of the initial values respectively.It was found inthis group that foetuses still remained in the uteri in 5 out of 6 rats 72 hours afterdrug administration,but they were smaller and free from the uteri as comparedwith controls.Concomitant treatment with 20 i.u.of HCG prevented the decrease in P in-duced by 15-methyl-PGF_(2α).The plasma P levels at 4,8,24 hours after HCGand 15-methyl-PGF_(2α)were not significantly different from those of the controls,Pregnancy was not interrupted in all the rats of this group.The size and the numberof the foetuses were similar to those of the controls.In another group,15-methyl-PGF_(2α)(20μg) was given as intravenous infusionto anaethetized pregnant rats,30 minutes after the infusion,the amount of P inutero-ovarian venous blood decreased from 1.271±0.154μg/10 min to 0.279±0.83μg/10 min.No significant change was observed in the blood flow of utero-ovarian vein.When HCG(20 i.u.)was administered intravenously,it stimulated the corpusluteum and produced a rise in the amount of P in utero-ovarian venous blood frominitial value 1.123±0.162μg/10 min to 1.496±0.018μg/10 min.Concomitanttreatment with HCG brought the P content in the utero-ovarian blood back to1.179±0.042μg/10 rain,a value similar to the initial one.The result demonstrated that 15-methyl-PGF_(2α)has a longer suppressing effecton plasma P level of the pregnant rats than 13-dehydro-ω-ethyl-PGF_(2α).Theeffect in terminating early pregnancy in rats seems related to the duration of thereduction of plasma P and the plasma P level 24 hours after PGs administration.The mechanism of the luteolytic effect of 15-methyl-PGF_(2α)appears to be littlerelated to the utero-ovarian venous blood flow, but probably related to the inhibi-tion of the effect of intrinsic gonadotropic hormone at the ovarian level.

15-甲-PGF_(2α)和13-去氢-ω 乙-PGF_(2α)在相同剂量时均能使妊娠7天的大鼠血浆孕酮浓度下降。15-甲-PGF_(α2)组于用药后4、8和24小时血浆孕酮浓度下降,分别为用药前的56.6%、43.7%和13.3%。在给药后72小时所有动物子宫中胚胎已被吸收。13-去氢ω-乙-PGF_(2α)组于用药后4、8和24小时血浆孕酮浓度分别为用药前的63.5%、34.4%和51.9%,给药后72小时大多数动物子宫中仍有胚胎,但胚胎比对照组显著为小,且多游离于子宫中。在给15-甲-PGF_(2α)前30分钟和第二次给15-甲-PGF_(2α)的同时,肌注 HOG 20国际单位,能完全对抗15-甲-PGF_(2α)的降低妊娠大鼠血浆孕酮浓度和抗早孕作用,给药后24小时内血浆孕酮浓度与对照组相似,全部动物维持妊娠,胚胎大小和数目也与对照组相似。恒速静注15-甲-PGF_(2α)(20微克)于麻醉妊娠大鼠,30分钟后已使子宫卵巢静脉血中孕酮含量由用药前1.271±0.154微克/10分钟下降到0.279±0.083微克/10分钟,给药后60分钟仍维持于低水平...

15-甲-PGF_(2α)和13-去氢-ω 乙-PGF_(2α)在相同剂量时均能使妊娠7天的大鼠血浆孕酮浓度下降。15-甲-PGF_(α2)组于用药后4、8和24小时血浆孕酮浓度下降,分别为用药前的56.6%、43.7%和13.3%。在给药后72小时所有动物子宫中胚胎已被吸收。13-去氢ω-乙-PGF_(2α)组于用药后4、8和24小时血浆孕酮浓度分别为用药前的63.5%、34.4%和51.9%,给药后72小时大多数动物子宫中仍有胚胎,但胚胎比对照组显著为小,且多游离于子宫中。在给15-甲-PGF_(2α)前30分钟和第二次给15-甲-PGF_(2α)的同时,肌注 HOG 20国际单位,能完全对抗15-甲-PGF_(2α)的降低妊娠大鼠血浆孕酮浓度和抗早孕作用,给药后24小时内血浆孕酮浓度与对照组相似,全部动物维持妊娠,胚胎大小和数目也与对照组相似。恒速静注15-甲-PGF_(2α)(20微克)于麻醉妊娠大鼠,30分钟后已使子宫卵巢静脉血中孕酮含量由用药前1.271±0.154微克/10分钟下降到0.279±0.083微克/10分钟,给药后60分钟仍维持于低水平。如预先静注 HOG 20国际单位,可使子宫卵巢静脉血中孕酮含量由用药前1.123±0.162微克/10分钟升高到1.496±0.018微克/10分钟,在 HCG作用的基础上再静脉恒速注入15-甲-PGF_(2α),虽可使子宫卵巢静脉血中孕酮含量下降到1.179±0.042微克/10分钟,但不能降低到

This paper reports the hormonal activity and the contraceptive action of 18-methylmestranol.In immature female mice, 18-methyl-mestranol was estrogenic as shown by the marked stimulation of uterine development. When compared with mestranol, its estrogenic potency was approximately 1/50. Given simultaneously with estradiol, 18-methylmestranol did not affect the uterine development induced by the estrogen, indicating that 18-methyl-mestranol had no anti-estrogenic action.In Clauberg test 18-methyl-mestranol did...

This paper reports the hormonal activity and the contraceptive action of 18-methylmestranol.In immature female mice, 18-methyl-mestranol was estrogenic as shown by the marked stimulation of uterine development. When compared with mestranol, its estrogenic potency was approximately 1/50. Given simultaneously with estradiol, 18-methylmestranol did not affect the uterine development induced by the estrogen, indicating that 18-methyl-mestranol had no anti-estrogenic action.In Clauberg test 18-methyl-mestranol did not stimulate the development of the rabbit endometrium but markedly inhibited the endometrium stimulating activity of norgestrel. Deciduomas in rats was provoked by injection of estrogen and norgestrel and by passing a thread through one uterine horn. Simultaneous administration of 18-methyl-mestranol with the norgestrel inhibited the development of the deciduoma. These results show that 18-methyl-mestranol possesses no progestational activity but is antiprogestogenic.Oral administration of 18-methyl-mestranol on the 1st, 2nd and 3rd day of gestation at the dosage of 1 mg/kg/day, completely prevented pregnancy in mice. When administered on the 6~8th day of gestation, 80~90% of the mice had their pregnancy interrupted. These experiments indicate that 18-methyl-mestranol is able to prevent implantation and interrupts early pregnancy.18-Methyl-mestranol was administered to mice on the 1st and 2nd day of gestation. On the 4th day of gestation, fertile eggs were seen in the oviduct in 4 out of 10 animals, while no egg was seen in the control group. Thus egg transport in the oviduct was slowed in the treated group, This slowing of egg transport might play a role inthe prevention of implantation.18-Methyl-mestranol was administered orally to mice at a daily dosage of 2 mg/kg for 14 days. No noticeable changes of body weight and morphology of the main viscera were observed. Dogs were given daily oral doses of 1 mg/kg for 14 days. At the end of this period, the blood picture, heart, SGPT and blood urea nitrogen were normal.

本文报告了18-甲基乙炔雌二醇-3-甲醚的激素活性和避孕作用。 18-甲炔雌甲醚在幼年雌性小鼠能明显刺激子宫发育,说明有雌激素活性。经与炔雌醇-3-甲醚作效价比较,结果指出其雌激素活性约为炔雌醇-3-甲醚的1/50。当与雌二醇同时应用时,18-甲炔雌甲醚并不能对抗雌二醇引起的子宫发育,说明没有抗雌激素活性。 用Claubcrg方法以及用大鼠蜕膜瘤方法进行的实验说明18-甲炔雌甲醚没有孕激素活性,但有明显的抗孕激素活性。 在小鼠妊娠第1、2、3天经口给18-甲炔雌甲醚,每日1 mg/kg小鼠不能怀孕。在妊娠第6、7、8天给18-甲炔雌甲醚,小鼠只有10~20%怀孕。说明有明显的抗着床和抗早孕作用。 在小鼠妊娠第1、2两天经口给18-甲炔雌甲醚,有4/10的动物在妊娠第四天输卵管中仍可见到受精卵,而对照组在妊娠第四天输卵管中都没有卵子,可见18-甲炔雌甲醚使受精卵在输卵管中的运行变慢,这一作用也可能是18-甲炔雌甲醚抗着床作用的一个原理。 经口给小鼠18-甲炔雌甲醚2 mg/kg,连给2周,对动物体重增长和各主要脏器形态都没有明显影响。经口给狗1 mg/...

本文报告了18-甲基乙炔雌二醇-3-甲醚的激素活性和避孕作用。 18-甲炔雌甲醚在幼年雌性小鼠能明显刺激子宫发育,说明有雌激素活性。经与炔雌醇-3-甲醚作效价比较,结果指出其雌激素活性约为炔雌醇-3-甲醚的1/50。当与雌二醇同时应用时,18-甲炔雌甲醚并不能对抗雌二醇引起的子宫发育,说明没有抗雌激素活性。 用Claubcrg方法以及用大鼠蜕膜瘤方法进行的实验说明18-甲炔雌甲醚没有孕激素活性,但有明显的抗孕激素活性。 在小鼠妊娠第1、2、3天经口给18-甲炔雌甲醚,每日1 mg/kg小鼠不能怀孕。在妊娠第6、7、8天给18-甲炔雌甲醚,小鼠只有10~20%怀孕。说明有明显的抗着床和抗早孕作用。 在小鼠妊娠第1、2两天经口给18-甲炔雌甲醚,有4/10的动物在妊娠第四天输卵管中仍可见到受精卵,而对照组在妊娠第四天输卵管中都没有卵子,可见18-甲炔雌甲醚使受精卵在输卵管中的运行变慢,这一作用也可能是18-甲炔雌甲醚抗着床作用的一个原理。 经口给小鼠18-甲炔雌甲醚2 mg/kg,连给2周,对动物体重增长和各主要脏器形态都没有明显影响。经口给狗1 mg/kg,连给两周,狗的血象、心脏和肝、肾功能没有出现异常。

In the present study, 17β-hydroxy-7α-methylandrost-5-en-3-one was shown to terminate pregnancy following subcutaneous administration of doses of 10 mg/kg on the 1st and 2nd days or the 7th and 8th days of pregnancy in rats and on the 1st and 2nd days or 4th and 5th days in mice. The ED_(50) of 17β-hydroxy-7α-methylandrost-5-en-3-one to terminate early pregnancy in mice was 0.159±0.055 mg/kg.

本工作表明17β-羟-7α-甲-5-雄烯-3-酮在妊娠小鼠、大鼠均有抗早孕和抗着床作用。在小鼠,17β-羟-7α-甲-5-雄烯-3-酮抗早孕作用的ED_(50)=0.159±0.055mg/kg。17β-羟-7α-甲-5-雄烯-3-酮在抗早孕剂量时能明显抑制假孕小鼠的蜕膜反应。甲地孕酮能完全对抗其抗早孕作用,也能完全对抗其抑制蜕膜反应的作用。早孕大鼠皮下注射17β-羟-7α-甲-5-雄烯-3-酮24小时后血浆孕酮浓度已明显下降。以上结果提示17β-羟-7α-甲-5-雄烯-3-酮抗早孕作用可能与其抑制孕酮合成有关。此外,本文对17β-羟-7α-甲-5-雄烯-3-酮的雌素活性和孕激素活性也进行了观察。

 
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