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诊断分界点
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  diagnostic cut-off
     A computer program for receiver operating characteristic curve analysis and diagnostic cut-off choice
     ROC曲线分析及诊断分界点确定程序
短句来源
     Results ①The program provided the functions of both parametric and non-parametric ROC curve analysis,determined three typical diagnostic cut-off points,and calculated sensitivity,specificity,accuracy,and other diagnostic indexes.
     结果 ①软件主要功能 :提供非参数和参数法两种ROC分析 ; 确定 3个典型诊断分界点 ;
短句来源
     Objective To investigate the optimum method to draw ROI and the optimum diagnostic cut-off on PET images.
     目的 探讨PET图像中勾画感兴趣区 (ROI)的最佳方法及标准摄取值 (SUV)最佳诊断分界点
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  “诊断分界点”译为未确定词的双语例句
     The area under receiver operating characteristic curve was 0 941.At the optimal cutoff point (370pg/ml),the diagnostic accuracy of plasma B NP concentration for differential diagnosis of cardiogenic acute dyspnea from pu lmogenic acute dyspnea was 86 2%.
     血浆BNP浓度诊断心源性急性呼吸困难的接受者工作特征 (receiveroperatingcharacteristic,ROC)曲线下面积为 0 94 1。 最适诊断分界点为 370pg/ml,诊断准确率为86 2 %。
短句来源
     Results :As single-item detection, the diagnosetic value of VEGF is the best, the cutoff of VEGF was 181.1pg/ml, the sensitivity of VEGF examination was 90.0%, the specificity was 86.7%.
     结果:在单项检测指标中,VEGF的诊断效能最好,其诊断分界点为181.1pg/ml,敏感性为90.0%,特异性为86.7%。
短句来源
     The cutoff value of DI,RI and PI was 1.10%,10.75% and 4.56%,and the sensitivity of DI examination was 89.3%,78.6%,75.0%,and the specificity was 89.5%,98.5%,84.2%,respectively.
     诊断分界点分别为1.10%、10.75%、4.56%,此时的敏感性分别为89.3%、78.6%、75.0%,特异性为89.5%、98.5%、84.2%;
短句来源
     Conclusion:The diagnostic values of Loyer and Lu CT diagnostic criteria for peripancreatic vascular invasion had no significantly statistical difference. The Lu CT diagnostic criteria was not very appropriate to evaluate peripancreatic venous invasion.
     结论:分别以Loyer和Lu血管分级CT标准对胰腺癌胰周血管侵犯进行分级,两者的诊断价值相同,Lu的CT诊断标准的最佳诊断分界点应在90°-180°之间,此外,它对胰周动脉的价值要比静脉差。
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  相似匹配句对
     A computer program for receiver operating characteristic curve analysis and diagnostic cut-off choice
     ROC曲线分析及诊断分界确定程序
短句来源
     Diagnostics?
     诊断
短句来源
     The principal points of diagnosis and surgery were also dicussed.
     讨论了诊断和手术的注意
短句来源
     The turning point to rise is benefit to diagnosis of the tumor.
     此分界对肿瘤生长阶段的诊断判定具有重大的意义。
短句来源
     Outlier Problem in Data Analysis
     数据分析中的异常诊断
短句来源
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  diagnostic cut-off
Diagnostic cut-off levels have been defined for food-specific serum immunoglobulin E antibody level and skin prick test wheal diameter that predict an adverse challenge outcome.
      
The area under the receiver operating characteristic (ROC) curve was evaluated and optimum diagnostic cut-off values determined.
      
The best operational diagnostic cut-off value was 2.25 mg/l.
      
In recent years the diagnostic cut-off value for fasting glucose has been reduced from 7.8 mmol/L to 7.1 mmol/L.
      
The objectives of this study were to establish the diagnostic cut-off criteria.
      
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Objective To evalute the value of rapid b edside assay of plasma B-type natriuretic peptide (BNP) concentration for diffe rentiating cardiogenic acute dyspnea from pulmogenic acute dyspnea and identify the optimal cut-off point.Methods A prospective study of 131 hospitalized patients with severe acute dyspnea was conducted.Bedside rap id assay of plasma BNP concentration was obtained in all patients.Two independe nt cardiologists blinded to patients BNP results reviewed all the clinical dat a and made the...

Objective To evalute the value of rapid b edside assay of plasma B-type natriuretic peptide (BNP) concentration for diffe rentiating cardiogenic acute dyspnea from pulmogenic acute dyspnea and identify the optimal cut-off point.Methods A prospective study of 131 hospitalized patients with severe acute dyspnea was conducted.Bedside rap id assay of plasma BNP concentration was obtained in all patients.Two independe nt cardiologists blinded to patients BNP results reviewed all the clinical dat a and made the etiological diagnosis of dyspnea.The concordant diagnoses were as the gold standard.Results Patients with cardiogenic ac ute dyspnea(n=54) had plasma BNP levels of 880 78±402 86pg/ml,which was signi fi cantly higher than that in the patients (n=62) with pulmogenic acute dyspnea 192 86±174 01pg/ml.The area under receiver operating characteristic curve was 0 941.At the optimal cutoff point (370pg/ml),the diagnostic accuracy of plasma B NP concentration for differential diagnosis of cardiogenic acute dyspnea from pu lmogenic acute dyspnea was 86 2%.Conclusions The rapi d assay of plsma BNP concentration is a useful measurement in differentiating ca rdiogenic acute dyspnea from pulmogenic acute dyspnea.

目的 探讨床边快速血浆B型钠尿肽 (B -typenatriureticpeptide,BNP)浓度检测对心源性和肺源性急性呼吸困难的鉴别诊断价值和最适诊断分界点。方法 前瞻性对急性呼吸困难急诊入院的 131名患者行床边快速血浆BNP浓度检测 ,两名心脏专家在不知其结果的情况下 ,根据患者的所有临床资料 ,独立作出病因诊断。一致性诊断作为确定诊断。结果 心源性急性呼吸困难组 54人 ,血浆BNP浓度为 880 78± 4 0 2 86pg/ml,肺源性急性呼吸困难组 6 2人 ,血浆BNP浓度为 192 86± 174 0 1pg/ml,两组比较P <0 0 1,具有显著性差异。血浆BNP浓度诊断心源性急性呼吸困难的接受者工作特征 (receiveroperatingcharacteristic,ROC)曲线下面积为 0 94 1。最适诊断分界点为 370pg/ml,诊断准确率为86 2 %。结论 床边快速血浆BNP浓度检测有助于心源性和肺源性急性呼吸困难的鉴别诊断

Objective To present a new computer program for ROC analysis and diagnostic cut-off choice. Methods The program algorithm was based on non-parametric and parametric ROC curve analysis theory. In order to validate the program,three groups of data were processed using SPSS,Analyse-it and the program. Finally the program was used to estimate the discrimination efficiency of the maximum standardized uptake value (SUV) and average SUV in PET FDG images for 126 cases of lung tumor patients (the benign 39,the malignant...

Objective To present a new computer program for ROC analysis and diagnostic cut-off choice. Methods The program algorithm was based on non-parametric and parametric ROC curve analysis theory. In order to validate the program,three groups of data were processed using SPSS,Analyse-it and the program. Finally the program was used to estimate the discrimination efficiency of the maximum standardized uptake value (SUV) and average SUV in PET FDG images for 126 cases of lung tumor patients (the benign 39,the malignant 87). Results ①The program provided the functions of both parametric and non-parametric ROC curve analysis,determined three typical diagnostic cut-off points,and calculated sensitivity,specificity,accuracy,and other diagnostic indexes. ②For the three groups of data,the test showed that the ROC analysis results with the program is same to those with SPSS and Analyse-it. ③Clinical application showed that the discriminative power of the average SUV was slightly higher than that of the maximum SUV,but the difference was not significant. Conclusion The program is accurate and credible and has more functions. It can perform both parametric and non-parametric ROC curve analysis,determine diagnostic cut-off point,and calculate the diagnostic indexes,such as sensitivity,specificity and accuracy.

目的 介绍一种新开发的ROC分析软件。方法 ①依据非参数法和参数法ROC分析理论建立算法。②对文献中 3套数据分别用本软件、SPSS及Analyse it软件进行ROC分析验证。③应用 :肺部良性 3 9,恶性 87例的PETFDG图像的SUV最大值及平均值鉴别良恶性效能评估。结果 ①软件主要功能 :提供非参数和参数法两种ROC分析 ;确定 3个典型诊断分界点 ;计算诊断符合率评价指标。②软件验证 :3个软件对 3套数据的分析结果完全相同。③应用实例 :SUV平均值的诊断效能稍好 ,但差异无显著性。结论 该软件不仅具有较完整的ROC分析功能 ,而且还具有确定诊断分界点 ,提供多种诊断符合率指标的功能 ,是目前性能较完整的软件。

Objective To investigate the optimum method to draw ROI and the optimum diagnostic cut-off on PET images. Methods PET FDG images of 126 patients with lung tumors (benign 39, malignant 87) were selected. For each tumor six ROIs were drawn with contour line at 50%, 60%, 70%, 80%, 90%, 100% of the maximum SUV, and the average SUVs were calculated. According to the results of ROC analysis, the optimum method of drawing ROI was determined. Three typical diagnostic SUV cut-off points were determined based on the...

Objective To investigate the optimum method to draw ROI and the optimum diagnostic cut-off on PET images. Methods PET FDG images of 126 patients with lung tumors (benign 39, malignant 87) were selected. For each tumor six ROIs were drawn with contour line at 50%, 60%, 70%, 80%, 90%, 100% of the maximum SUV, and the average SUVs were calculated. According to the results of ROC analysis, the optimum method of drawing ROI was determined. Three typical diagnostic SUV cut-off points were determined based on the maximum accuracy, the maximum Youden's index and the intersection of sensitivity and specificity. Results ①The area under the ROC curve was maximum at the SUV in the ROI drawn with contour line at 70% of the maximum SUV, and the three typical cut-off SUVs were 2.075, 2.825, 2.919, respectively. ②Among the six ROIs with contour line, the accuracy, Youden's index and the ratio of the positive likelihood ratio (LR+) to the negative likelihood ratio (LR-) at three typical SUVs cut-off had maximum values at the ROI drawn with contour line at 70%. Conclusion The optimum methods of drawing ROI impersonally and determining optimum diagnostic cut-off are proposed, which can be used in quantitative analysis and clinical diagnosis with PET images.

目的 探讨PET图像中勾画感兴趣区 (ROI)的最佳方法及标准摄取值 (SUV)最佳诊断分界点。方法 以PETFDG 12 6例肺部肿瘤图像为例说明 ,由SUVmax的百分比 ( 5 0 %~ 10 0 % )为等高线值勾画ROI ,得各SUV均值 ;由受试者工作特性 (ROC)曲线分析确定ROI最佳画法 ;由准确率最大值、Youden’s指数最大值及敏感性与特异性交点确定分界点。结果 ①最优ROI :70 %等高线所画ROI的SUV具有最大ROC曲线下面积。其 3个典型SUV分界点值分别为 :2 .0 75、2 .82 5、2 .919。② 3个典型分界点的准确率、Youden’s指数和阳性概率比 /阴性概率比均在 70 %等高线出现较大值。结论 提出一套客观画取ROI、确定最佳等高线值、及最佳分界点的方法 ,可用于各种示踪剂PET图像中的各种定量指标

 
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