The changes of serum aminotransferase (ALT),albumin (ALB),Laminin (LN),hyaluronic acid (HA) and Ⅳ collagen (CⅣ) as well as the content of hepatic hydroxyproline (HYP) and the formation of hepatic fibrosis were comparatively observed to evaluate the effects of SEY on hepatic fibrogenesis in rats.
2, To observe different characteristics of clinical manifestation and hepatic fibrosis in congenital biliary dilation (CBD) between infants and older child, and to discuss the role of PBM in formation of hepatic fibrosis.
They were classified into 5 stages on the basis of liver fibrosis, and found that there were no remarkable differences of PLD among different stages ( F=1.82,P >0.05).
Conclusions: common serum biochemical indexes ALT, AST, Alb, Tbil, PT can reflect histological inflammatory activity, and Alb, PT allow estimation of the extend of fibrosis in chronic hepatitis.
Objective To investigate the echo changes between liver and kidney parenchyma on patients with liver fibrosis and to find a new examination method for the diagnosis of liver fibrosis.
The serum level of TGF-β1 was positively correlated with those of HA,LN and IV-C. The expression of TGF-β1 in the liver tissue was positively correlated with the staging of fibrotic liver.
The Ile50Val polymorphism of the IL4RA gene was tested for association with chronic viral hepatitis and the character of its progression (the stage of hepatic fibrosis).
In hepatic fibrosis, the connective tissue biomatrix of the liver changes from the normal matrix, rich in basement membrane collagens, to a matrix enriched in interstitial fibrillar collagens.