METHODS: Based on the successful establishment of mouse Cbfa1 promoter luciferase reporter plasmid, the influences of FGF 9 on Cbfa1 gene promoter activity and mRNA expression, as well as the effect of MAPK signal conduction pathway, were determined with the technique of transient transfection and reverse transcription polymerase chain reaction(RT PCR) respectively.
Objective To detect the effects of interferon-alpha subtypes(IFN-α 2b,IFN-α 2a and IFN-α 1b)on signaling transduction molecule STAT1mRNA expression in HepG2 cells by real-time fluorescence quatitive PCR(FQ-PCR).
Objectives To investigate the effects of different subtypes IFN α(IFN α2b,IFN α2a,and IFN α 1b)transduction molecular STAT1,STAT2,IFNAR,PKR,and RNase L,and to study the differences of their antiviral effects and to evaluate the key signaling transduction molecules.
1. F9315 is Required for Flowering-time Control and Trichome Development in Arabidopsis Thaliana 2. F9231, An Important Gene That is Involved in the Sugar Signaling Transduction Pathway in Arabidopsis Thaliana
In conclusion, all results indicate that BeDREB1 and BeDREB2 genes isolated from treated Bermuda grass are new members of the DREB transcription activator family, which may play very important roles in signal transduction related to stresses.
Hemin and thermal stress might regulate JWA expression via distinct intracellular signal transduction pathways.
Quantitatively describing the signal transduction process is important for understanding the mechanism of signal regulation in cells, and thus, poses both a challenge and an opportunity for chemical and biochemical engineers.
The data suggest an important role of the lipoxygenase metabolism in signal transduction of the anti-injury defense system in dormant potato tubers.
A hypothesis is advanced, according to which determinants of antibiotic resistance play a key role in the network of signal transduction systems of actinomycetes.
This paper provides important clues which are helpful to understanding the changes in gene expression, signal conduction and metabolism characteristics during T.
The self-renewal and pluripotency of embryonic stem cells (ESCs) is regulated by a network, which consists of a series of cell factors in microenviroments, a chain of transcription factors and certain signal conduction pathways.
The mechanism may be that the expression of resistin is partly controlled by protein kinase C signal conduction pathway.
From a comparison of CL and OR1 latencies, justified on the grounds of independent stimulation, a strict correlation was found for signal conduction properties in the claustral and LGN pathways running to a given striate neuron.
Membrane-stabilizing drugs show an effect on signal conduction during hypoxia and need further exploration.
Chronic hyperinsulinism induced down-regulation of insulin post-receptor signaling transduction in Hep G2 cells
Mechanisms of resistance to TGF-β caused by modulation of cell cycle regulators and/or inactivation of components of the TGF-β signaling transduction pathway such as C-myc and Smad4 are not well understood.
Puerarin appears to be able to reduce cell proliferation and vascular remodeling possibly through PKC signaling transduction pathway.
Hence, the development of tissue-specific gene inactivation strategies should facilitate the study of the potential role of PTPases in β-cell insulin signaling transduction.
A rapidly expanding body of study indicates that the functions of CRMPs are not solely limited to the signaling transduction of the Sema3A guidance cue.