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呼吸系统疾病
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卡介苗多糖核酸
相关语句
  bcg-psn
     Effect of BCG-PSN on T_H1 and T_H2 cytokine responses of peripheral blood mononuclear cells from atopic asthmatics
     卡介苗多糖核酸对过敏性支气管哮喘外周血单个核细胞T_H1/T_H2反应的作用
短句来源
     Methods BCG-PSN was injected intramuscularlly in 17 patients with asthma and 15 patients with COPD. FEV_1%pred was measured and serum concentrations of IL-4 and IFN-γ were detected before and after treatment. The intracellular expressions of IFN-γ and IL-4 in Th1/Th2 cell were assayed by flowcytometry.
     方法分别对17例哮喘和15例COPD患者进行卡介苗多糖核酸注射治疗,治疗前后测定FEV1%pred、血浆IL-4、IFNγ-,并用流式细胞术检测Th1/Th2细胞内因子IFNγ-/IL-4的表达率。
短句来源
     Conclusion BCG-PSN has dual immuno-modulatory effects to enhance Th1 cell function in(asthma)(whereas) to suppress Th1 cell function in COPD.
     结论卡介苗多糖核酸能增强哮喘患者Th1细胞功能,同时能降低COPD患者Th1细胞功能,具有双向调节功能。
短句来源
     Objective To study the functions of two different kinds of drugs on regulating TH1/TH2 of children with asthma by comparing the effects of bacille calmette-guerin-polysaccharide-nucleic acid (BCG-PSN) and attenuated BCG.
     目的探讨卡介苗多糖核酸(BCG-PSN)与减毒活卡介苗治疗儿童哮喘临床疗效及其对哮喘患儿TH1/TH2调节的差异。
短句来源
     Objective To explore the mechanism of antiallergic action of BCG-polysaccharide nucleic acid (BCG-PSN) in allergic rhinitis.
     目的 观察卡介苗多糖核酸(BCG PSN)治疗变应性鼻炎的机制及其疗效。
短句来源
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  bcg-polysaccharide nucleic acid
     PURPOSE: To investigate the regulation of BCG-polysaccharide nucleic acid and dexamethasone on Th1/Th2 cytokines from peripheral blood mononuclear cells in oral lichen planus. METHODS: Peripheral blood mononuclear cells (PBMC) were isolated from OLP patients and healthy controls by density gradient sedimentation.
     目的:研究口腔扁平苔藓(oral lichen planus,OLP)的Th1/Th2免疫应答模式,探讨卡介苗多糖核酸(BCG-polysaccharide nucleic acid,BCG-PSN)和地塞米松对OLP患者外周血单个核细胞Th1/Th2细胞因子的调节作用。
     Regulation of BCG-polysaccharide nucleic acid on Th_1/ Th_2 cytokine imbalance of allergic rhinitic patients
     卡介苗多糖核酸对变应性鼻炎病人Th_1/Th_2失衡状态的调节
短句来源
     Regulation of BCG -polysaccharide nucleic acid and dexamethasone on Th1/Th2 cytokines from peripheral blood mononuclear cells in oral lichen planus
     卡介苗多糖核酸和地塞米松对口腔扁平苔藓外周血单个核细胞Th1/Th2细胞因子的调节作用
     Objective To explore the mechanism of antiallergic action of BCG-polysaccharide nucleic acid (BCG-PSN) in allergic rhinitis.
     目的 观察卡介苗多糖核酸(BCG PSN)治疗变应性鼻炎的机制及其疗效。
短句来源
     Clinical investigation of preventive effect of BCG-Polysaccharide Nucleic Acid in 102 children with repeated child Bronchial asthma
     卡介苗多糖核酸注射液预防小儿哮喘发作102例临床观察
短句来源
  “卡介苗多糖核酸”译为未确定词的双语例句
     The effect and significance of BCG polysaccharide nucleic acid to SIL-2R and subsets of T cells of children with recurrent respiratory tract infections
     卡介苗多糖核酸对反复呼吸道感染SIL-2R、T细胞亚群的影响及意义
短句来源
     Objective To observe the clinical effects of using the vaccinum calmette guerini polysaccharide nucleic acid to prevent and treat community children repeated respiratory track infection.
     目的观察卡介苗多糖核酸在预防和治疗社区儿童反复呼吸道感染的临床疗效。
短句来源
     These 65 are divided into 2 groups for study. One group is observed group, 35 patients are treated by muscle injecting 1 ml vaccinum calmette guerini for one time, every 2 days, and the continuous 3 months as one treatment period.
     分2组研究,设观察组35例,采用卡介苗多糖核酸治疗,1ml/次,隔日肌注,连用3个月为1疗程。
短句来源
     Conclusions Using vaccinum calmette guerini to prevent and treat community children repeated respiratory track infection is effective, safe and no poisonous or side-effects.
     结论卡介苗多糖核酸预防和治疗社区儿童反复呼吸道感染有效、安全无毒副作用。
短句来源
     Effect of Amylose Nucleic Acid of BCG Vaccine on the Immunologic Function of COPD Patients in Remission Stage
     卡介苗多糖核酸对COPD缓解期患者免疫功能的影响
短句来源
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  bcg-psn
A comparative study on the effect of BCG-PSN and thymopeptides on T-lymphocyte subsets of normal and immunosuppressed mice
      
The results showed that both BCG-PSN and thymopeptides could decrease the proportion of CD4+ CD8+ T-lymphocyte subsets in the thymus, at the same time increase CD4+ T-lymphocyte, CD8+ T-lymphocyte proportion in the three tissues.
      
The fluctuation in amplitude was greater in thymopeptides group than that in BCG-PSN group.
      


Hemorheological changes were assessed in 72 cases of bronehial cancinoma and 50referents. It showed that patieats with bronchial camcinoma had higher levels of viscosityemia. Among them. 37 cases were treated by BCG-PSN combined with the,generaltreatment (the experimertal group), and 35 cases were treated by the general. Treatment (the control group). After treatment, it showed thet the,experimental group hada great improvement in hemorheology. лb, лp, Fig. HCT came down to normal. Thetherapeutic effect of the...

Hemorheological changes were assessed in 72 cases of bronehial cancinoma and 50referents. It showed that patieats with bronchial camcinoma had higher levels of viscosityemia. Among them. 37 cases were treated by BCG-PSN combined with the,generaltreatment (the experimertal group), and 35 cases were treated by the general. Treatment (the control group). After treatment, it showed thet the,experimental group hada great improvement in hemorheology. лb, лp, Fig. HCT came down to normal. Thetherapeutic effect of the comtrol group was not so obvious. It suggested that BCGPSN treatment can be beneficied on the,high levels of,viscositymia in bronchial cancinoma.

对72例肺癌患者的血液流变学(下称血流变)检测,以50例健康人作对照,结果表明肺癌患者存在高粘血症。对其中37例患者除常规治疗外加用卡介苗多糖核酸(BCG—PSN)治疗(试验组),另35例仅作常规治疗(对照组)。观测两组治疗后血流变学变化。结果表明:试验组血流变有明显改善,其中μb、μg、Fig、HCT等指标下降,与健康组相比无明显差异(P>0.05)。而对照组无明显变化。以上提示卡介苗多糖核酸对肺癌高粘滞血症的治疗有积极意义,可作为肺癌的一种辅助治疗手段。

Acupoint - injection of bacille Calmette-guerin polysaccharide nucleic acid (BCG - PSN) injectio at Zusanli (ST 36), Dingchuan (EX -B 1) and Feishu (BL 13) points were used for treatment of 32 cases of bronchial asthma in hot summer days and T - lymphocyte subgroups and serum IgA, IgG, IgM and C3 contents were detected before and after treatment. Results indicated that the total effective rate was 84. 37%: acupoint-injection of PSN at Zusanli (ST 36), Dingchuan (EX -B 1) and Feishu (BL 13) points could increase...

Acupoint - injection of bacille Calmette-guerin polysaccharide nucleic acid (BCG - PSN) injectio at Zusanli (ST 36), Dingchuan (EX -B 1) and Feishu (BL 13) points were used for treatment of 32 cases of bronchial asthma in hot summer days and T - lymphocyte subgroups and serum IgA, IgG, IgM and C3 contents were detected before and after treatment. Results indicated that the total effective rate was 84. 37%: acupoint-injection of PSN at Zusanli (ST 36), Dingchuan (EX -B 1) and Feishu (BL 13) points could increase the lowered CD8+ (P <0. 01) ; decrease the increased CD4 + /CD8+ ratio (P<0. 01) ; obviously lower IgG content (P<.0. 01) and increase C3 content (P < 0. 05). It is suggested that this method can regulate immunologic function of the organism. The method of acupoint - injection provides a simple and effective therapy for patients of bronchial asthma.

伏天对32例支气管哮喘患者用卡介苗多糖核酸注射液(BCG—PSN,简称PSN)穴位注射足三里、定喘穴、肺俞穴,总有效率84.37%。同时检测患者治疗前后的T细胞亚群、血清IgA、IgG、IgM和补体C_3。结果表明,伏天用PSN穴位注射能使患者过低的CDS_8~+升高(P<0.01);升高的CD_4~+/CD_8~+比值降低(P<0.01);IgG明显下降(P<0.01);C_3明显升高(P<0.05)。证明本方法能调节机体免疫功能,为支气管哮喘病人的治疗提供了一种简便有效的方法。

In this study,the comparison of clinical effects was carried out about mycobacterium bovine bacillus Calmette-Guerin (BCG)and its components,including polysaccaride nucleic acid(BCG-PSN)and heat shock protein 65(HSP65),on the maturation of cord blood monocyte-derived dendritic cells(DCs). Because they can help us to understand the BCG and its components effects on the neonatal immunefunction.Purified cord blood CD14+ monocytes isolated by immunomagnetic beads were cultured in serum and hormone-free medium(DMEM-F12)with...

In this study,the comparison of clinical effects was carried out about mycobacterium bovine bacillus Calmette-Guerin (BCG)and its components,including polysaccaride nucleic acid(BCG-PSN)and heat shock protein 65(HSP65),on the maturation of cord blood monocyte-derived dendritic cells(DCs). Because they can help us to understand the BCG and its components effects on the neonatal immunefunction.Purified cord blood CD14+ monocytes isolated by immunomagnetic beads were cultured in serum and hormone-free medium(DMEM-F12)with IL-4 and GM-CSF for 7 days.On the 5th day of culture,BCG and its components were added for further 2 days culture.The phenotype of the cord blood monocyte-derived DCs expressed was assayed with three-color flow cytometry.In comparison with the immature cord blood monocyte-derived DCs,the BCG induced the maturation of cord blood monocyte-derived DCs can significantly up-regulate the expression of CD83,CD86 and MHC class Ⅱmolecules and down-regulate the expression of mannose receptor(MR).But,its components had no effect on cord blood monocyte-derived DCs maturation.It is possible that through promoting DC maturation,BCG can modulate the development of neonatal naive T cell.But its components have no role in the maturation process of cord blood DCs.

通过比较卡介苗 (BCG)、卡介苗多糖核酸提取物 (BCG_PSN)以及热休克蛋白65(HSP65)对脐血单核细胞转化的树突状细胞成熟的影响 ,以探讨BCG及其有效成分对新生儿免疫功能的作用。经体外分离 ,诱导19例健康足月新生儿CD14 +单核细胞分化成为未成熟树突状细胞 ,并观察BCG、BCG_PSN和HSP65对其成熟的影响。结果 :BCG可通过上调CD83、CD86和MHCⅡ类抗原 ,下调甘露聚糖受体 (MR)促进脐血单核细胞转化的树突状细胞成熟 ,BCG_PSN和HSP65不能促进脐血树突状细胞分化成熟。提示BCG可能通过促进脐血树突状细胞的成熟 ,影响新生儿T细胞功能发育 ,而BCG_PSN和HSP65并无此作用

 
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