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生化工程学
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     Chaos Engineering
     混沌工程学
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     biochemical coupling;
     生化偶联 ;
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     State of the arts in rehabilitation engineering science
     康复工程学的研究与发展
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     Biochemical Application of Bagasse
     蔗渣的生化利用
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  biochemical engineering
We have concentrated on biochemical engineering parameters of immobilized biocatalysts, which are important with respect to their application in industrial processes.
      
Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronect
      
Biochemical engineering of the acyl side chain of neuraminic acids activates β1-integrins (VLA4 or VLA5), resulting in an increased adhesion of HL60 cells to fibronectin.
      
Hence, application of biochemical engineering principles and method standardisation efforts become important.
      
Ghose - the initiator of Biotechnology and Biochemical Engineering research in India
      
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The impressing from immobilized medium and moving solution might cause protein conformational change and accompanying loss of protein activity during separation by chromatographic processes. At the same time, the denatured protein might refold to gain their native structure and total activity when they pass through the chromatographic column at suitable operation condition. This review focuses on recent advances in column separation and refolding, which have shown promising results on activity recovery from...

The impressing from immobilized medium and moving solution might cause protein conformational change and accompanying loss of protein activity during separation by chromatographic processes. At the same time, the denatured protein might refold to gain their native structure and total activity when they pass through the chromatographic column at suitable operation condition. This review focuses on recent advances in column separation and refolding, which have shown promising results on activity recovery from native protein and refolding yield from inclusion bodies. Suitable chromatographic medium and optimized operation system will affect conformational change and improve the yield of active proteins, which are valuable on both laboratory research and commercial productivity.

在层析分离过程中 ,层析的固相介质和溶液环境会引起蛋白质的结构变化 :天然的蛋白质可能会降低活性甚至完全失去活性 ,而结构变化了的蛋白质也可能重新折叠恢复活性 .此类现象已经引起研究者特别是生化工程学家的关注 ,层析介质的种类和操作手段是影响此两个过程的关键因素 .利用不同的层析方法 ,对不同的蛋白质采取相应的措施有利于提高活性蛋白质的回收率 ,具有重要的理论和应用价值 .

 
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