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   肾间质成纤维细胞 的翻译结果: 查询用时:0.066秒
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肾间质成纤维细胞     
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  renal interstitial fibroblasts
     Effects of TGF-β1 on cellular proliferation and expression of type Ⅲcollagen by cultured rat renal interstitial fibroblasts
     TGF-β1对肾间质成纤维细胞Ⅲ型胶原表达的影响
短句来源
     ObjectiveTo observe the effects of activin A (ACT-A) and follistain (FS) on proliferating and secreting extracelluar matrix of cultured rat renal interstitial fibroblasts.
     目的:观察激活素A(Activin A,ACT-A)及其抑制剂卵泡抑素(Follistain,FS)对大鼠肾间质成纤维细胞增殖、活化及产生细胞外基质(Extracellular matrix,ECM)的影响,以探讨ACT-A在肾间质纤维化发生机制中的作用。
短句来源
     Lipoxin A4 induces apoptosis of rat renal interstitial fibroblasts via up regulation of Smac expression
     脂氧素A4通过上调Smac表达诱导肾间质成纤维细胞凋亡
短句来源
     Transforming Growth Factor β1 Regulates the Expression of Tissue Transglutaminase in the Human Renal Interstitial Fibroblasts
     转化生长因子β1对人肾间质成纤维细胞组织型转谷氨酰胺酶表达的调节
短句来源
     Objective To study the effects on the migration of human renal interstitial fibroblasts (hRIF) after transfer of angiotensin Ⅱ (AngⅡ) type 2 receptor (AT2R).
     目的 探讨血管紧张素Ⅱ (AngⅡ ) 2型受体 (AT2R)基因表达对人肾间质成纤维细胞 (hRIF)迁移活性的影响。
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  interstitial fibroblasts
     Effects of TGF-β1 on cellular proliferation and expression of type Ⅲcollagen by cultured rat renal interstitial fibroblasts
     TGF-β1对肾间质成纤维细胞Ⅲ型胶原表达的影响
短句来源
     ObjectiveTo observe the effects of activin A (ACT-A) and follistain (FS) on proliferating and secreting extracelluar matrix of cultured rat renal interstitial fibroblasts.
     目的:观察激活素A(Activin A,ACT-A)及其抑制剂卵泡抑素(Follistain,FS)对大鼠肾间质成纤维细胞增殖、活化及产生细胞外基质(Extracellular matrix,ECM)的影响,以探讨ACT-A在肾间质纤维化发生机制中的作用。
短句来源
     Lipoxin A4 induces apoptosis of rat renal interstitial fibroblasts via up regulation of Smac expression
     脂氧素A4通过上调Smac表达诱导肾间质成纤维细胞凋亡
短句来源
     Transforming Growth Factor β1 Regulates the Expression of Tissue Transglutaminase in the Human Renal Interstitial Fibroblasts
     转化生长因子β1对人肾间质成纤维细胞组织型转谷氨酰胺酶表达的调节
短句来源
     Objective To study the effects on the migration of human renal interstitial fibroblasts (hRIF) after transfer of angiotensin Ⅱ (AngⅡ) type 2 receptor (AT2R).
     目的 探讨血管紧张素Ⅱ (AngⅡ ) 2型受体 (AT2R)基因表达对人肾间质成纤维细胞 (hRIF)迁移活性的影响。
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  renal interstitial fibroblast
     Objective To explore the effect of Rhein on TGF-β1-induced renal interstitial fibroblast activation.
     目的研究大黄酸(Rhein)抑制转化生长因子β1(TGF-β1)激活大鼠肾间质成纤维细胞(NRK-49F)作用及探讨大黄治疗肾脏病的作用机制。
短句来源
     Effects of simvastatin on proliferation and α_5 integrin expression of renal interstitial fibroblast in rats
     辛伐他汀对大鼠肾间质成纤维细胞增殖及α_5整合素表达的影响
短句来源
     The proliferation and expression of α5 integrin in stimulated renal interstitial fibroblast were measured with MTT method,FCM and RT-PCR,repectively.
     方法不同浓度辛伐他汀加入到含有TGF-β1培养液培养的大鼠肾间质成纤维细胞,分别采用MTT法及细胞流式仪检测细胞的增殖,RT-PCR法检测大鼠肾间质成纤维细胞表面α5整合素的表达。
短句来源
     Objective : To reveal the mechanism of action that fucoidan counteracts renal interstitium fibrosis,we investigated the effects of fucoidan(FPS) on proliferation , apoptosis and expression of fibronectin(FN),laminin(LN) and transforming growth factorβ1(TGF-β1) in the human renal interstitial fibroblast(HRIF) in vitro.
     目的:研究褐藻多糖硫酸酯(FPS)对体外培养的人肾间质成纤维细胞(HRIF)增殖的影响,对其分泌纤维连接蛋白(FN)、层粘连蛋白(LN)、转化生长因子β1(TGF-β1)的影响,以及对HRIF凋亡的影响,以期探讨FPS抗肾间质纤维化的作用机理,为药物的进一步开发提供分子细胞学理论依据。
短句来源
     Conclusion: Hypoxia could stimulate the expression of CTGF in human renal interstitial fibroblast through the activation of p38 MARK signaling pathway.
     结论:低氧可刺激人肾间质成纤维细胞表达CTGF,并且该作用依赖p38通路的活化。
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  renal fibroblast
     The results showed that expression of Fas/APO1 was strong in T24 cell line and in primary in vitro cultured renal fibroblast, medium in PC3M cell line, weak in RCC949 and BIU87 cell lines and negative in GRC1 and EJ cell lines.
     结果显示原代培养正常肾间质成纤维细胞和T24细胞系Fas/APO1分子表达较强,PC3M属中等强度表达,RCC949与BIU87属微弱表达,而EJ及GRC1则不表达。
短句来源
     TGFβ1 promoted expression of collagen I and HSP47 of renal fibroblast in dose-dependent manner range from 0.1ng/ml to 5ng/ml.
     (2)在0.1~5ng/ml范围内,TGF-β1以剂量依赖方式促进培养的人肾间质成纤维细胞表达HSP47和I型胶原mRNA。
短句来源
     To explore the role of Fas/APO1 in the occurrence and progression of human urinary malignant tumors, expression of Fas/APO1 was tested with immunocytochemical technique in 6 kinds of urinary tumor cell lines consisting of bladder cancer (T24, EJ, BIU87), renal cell carcinoma (GRC1,RCC949),prostatic cancer (PC3M) and a primary in vitro cultured normal renal fibroblast.
     为了探讨Fas/APO1在泌尿系恶性肿瘤发生发展中的作用,采用免疫细胞化学方法对6种泌尿系肿瘤细胞,膀胱癌(T24,EJ,BIU87),肾癌(GRC1,RCC949),前列腺癌(PC3M)和一种原代培养正常肾间质成纤维细胞Fas/APO1分子的表达进行了检测。
短句来源
     Conclusion Possibly through abrogating TGF-β1/Smads signaling pathway, PPARγ agonists inhibit TGF-β1-induced renal fibroblast extracellular matrix synthesis and may play a potential role in preventing tubulointerstitial fibrosis as a novel approach to prevent the progress of end stage renal dysfunction.
     结论PPARγ激动剂可以抑制TGFβ1诱导的肾间质成纤维细胞细胞外基质合成,其机制可能与阻断TGF-β1/Smad信号途径有关,提示PPARγ激动剂具有抗肾间质纤维化的潜在作用,可能成为延缓终末期肾功能衰竭的治疗新手段之一。
短句来源
     Results Mast cell tryptase promoted proliferation and expression of collagen I of renal fibroblast in heparin-dependent manner.
     结果 肥大细胞类胰蛋白酶可促进肾间质成纤维细胞增生和I型胶原mRNA的表达,且依赖于肝素的存在。
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  renal interstitial fibroblasts
Transmission electron microscopy of autopsy specimens from the SCHADD patient demonstrated that most renal interstitial fibroblasts and ~50% of fibroblasts in the heart had microvesicular steatosis.
      
Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-β
      
Therefore, over-expression of PHB suppresses renal interstitial fibroblasts proliferation and cell phenotypic change induced by TGF-β1, which indicates PHB as a potential therapeutic target to halt the progression of TIF.
      
Erk-1/2 activation is sufficient for MMP-9 induction in renal interstitial fibroblasts.
      
HGF does not increase the protein levels of Smad transcriptional co-repressors in renal interstitial fibroblasts.
      
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  interstitial fibroblasts
The effects of cardiac myocytes on interstitial fibroblasts in toxic iron overload
      
There is increasing evidence that lipid interstitial fibroblasts play an important role in injury-repair mechanisms in various organ systems.
      
We detected lacZ expression exclusively in the interstitial fibroblasts near the PTCs of the kidney by immunoelectron microscopy.
      
Vimentin-positive cells are identified as interstitial fibroblasts, capillary endothelia and other vascular wall cells as well as practically all glomerular cells, including podocytes and mesangial cells.
      
MMP-2 was mildly expressed in the interstitial fibroblasts and MMP-3 was faintly stained in the extracellular matrix of the synovial membrane.
      
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  renal interstitial fibroblast
Characterization of renal interstitial fibroblast-specific protein?1/S100A4-positive cells in healthy and inflamed rodent kidney
      
HGF blocks activated Smad-2 nuclear translocation and accumulation in renal interstitial fibroblast NRK-49F cells.
      
Panax notoginseng saponins induced of human renal interstitial fibroblast and its mechanisms.
      
This, in turn, is dependent on Erk-1/2 activation initiated by HGF in renal interstitial fibroblast cells.
      
Using rat renal interstitial fibroblast NRK-49F cells as a model system, Figure 10.
      
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  renal fibroblast
LLCPK1, MDCK, renal fibroblast and endothelial cell lines were cultured under standard conditions.
      
The remodeling model consisted of a renal fibroblast-populated collagen lattice (FPCL).
      
Illustrative western blot demonstrating that both 10 and 100 ng/ml H2 relaxin decrease renal fibroblast expression of -SMA.
      
In addition, we investigated the possible role of tryptase in renal fibroblast proliferation and matrix protein synthesis in vitro.
      
In our previous work, we demonstrated the predominant role of KiRas in the stimulated proliferation of the Vero primate renal fibroblast cell line.
      
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