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诱导痰
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  induced sputum
     and reduction in the number of all cells (246±42)×108/L vs (225±33) ×108/L, P <0.01), neutrophil propo tion (75.6±6.7)% vs (71.4±6.5)%, P <0.01) in induced sputum.
     诱导痰中细胞总数治疗前:(246±42)×108/L治疗后:(225±33)×108/L, P<0.01),中性粒细胞分类治疗前:(75.6±6.7)%,治疗后:(71.4±6.5)%, P<0.01)均明显下降。
短句来源
     The level of IL-5 in induced sputum in asthmatics(53.3±24.2)ng/L was higher than those in healthy volunteers(20.2±4.1)ng/L and in COPD(29.8±4.7)ng/L(P <0.05).
     哮喘组诱导痰中IL-5水平(53.3±24.2)ng/L显著高于对照组(20.2±4.1)ng/L和COPD组(29.8±4.7)ng/L(P<0.05)。
短句来源
     ResultsConcentrations of LTB4 in induced sputum[(794±305)pg/mg·pro] and plasma[(5 219±1 185)ng/L] in group C were significantly higher than those in group H[(347±169)pg/mg·pro,(2 283±489)ng/L,all P<0.05].
     结果(1)C组诱导痰及血浆的LTB4水平分别为(794±305)pg/mg·pro、(5219±1185)ng/L,均显著高于H组[(155±64)pg/mg·pro、(2283±489)ng/L,P均<0·05]。
短句来源
     Impact of Peripheral Blood CD4~+CD25~+ Regulatory T Cells and Neutrophil of Induced Sputum on the Pathogenesis of Childhood Asthma
     外周血CD4~+CD25~+调节性T细胞和诱导痰中性粒细胞在儿童哮喘发病中的作用
短句来源
     The pre- and post-therapy concentrations of LTB4 in induced sputum and plasma in group CA were (812±592),(657±459) pg/mg·pro and (5 422±935),(4 589±1 057)ng/L,respectively;
     (3)CA组在茶碱治疗前、后诱导痰LTB4水平分别为(812±592)、(657±459)pg/mg·pro,血浆水平为(5422±935)、(4589±1057)ng/L;
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  sputum induction
     SaO_2 were (98.0±1.0)% and(96.3±2.5)%,respectively before and after sputum induction(P>0.05).
     诱导痰前、后SaO2分别为(98.0±1.0)%和(96.3±2.5)%,无显著性差异(P>0.05)。
短句来源
     SaO_2 were(96.0±1.2)% and(93.5±1.9)%,respectively before and after sputum induction with no significant difference.
     诱导痰前、后SaO2分别为(96.0±1.2)%和(93.5±1.9)%,无显著性差异(P>0.05)。
短句来源
     In patients with mild to moderate(asthma),the FEV_1%pred were(83.3±12.1)% and(72.5±15.0)%,respectively before and after sputum induction(P<0.01).
     轻中度组诱导痰前、后FEV1%pred分别为(83.3±12.1)%和(72.5±15.0)%,有非常显著性差异(P<0.01);
短句来源
     Results In patients with severe asthma,the percent predicted of FEV_1(FEV_1%pred) were(60.8±15.8)% and(53.6±15.9)% before and after sputum induction,respectively,which were different significantly(P<0.01).
     结果重度组诱导痰前、后FEV1占预计值百分比(FEV1%pred)分别为(60.8±15.8)%和(53.6±15.9)%,有非常显著性差异(P<0.01);
短句来源
     Results:No significant differences in lung function,HR,RR and SaO_(2) after sputum induction were found in patients with asthma and COPD(P>0.05).
     结果:哮喘和COPD患者诱导痰前后肺功能、HR、RR和SaO2均无显著变化(P>0.05)。
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  “诱导痰”译为未确定词的双语例句
     The difference of LTC_4 level was also significant when CVA group (0.65±0.62)μg/L was compared with EB group (0.39±0.61)μg/L ( P< 0.05) and healthy group(0.15±0.11)μg/L(P<0.01).
     CVA组诱导痰中的LTC4浓度为(0.65±0.62)μg/L,EB组为(0.39±0.61)μg/L,对照组为(0.15±0.11)μg/L,3组间比较差异有统计学意义(P分别<0.05、0.01);
短句来源
     The concentration of sputum ECP was (0.62±0.66) mg/L in EB group, (1.27±1.74)mg/L in CVA group, (0.07±0.10)mg/L in healthy group, the difference among the three groups being significant (P<0.01).
     EB组诱导痰中的ECP浓度为(0.62±0.66)mg/L、CVA组为(1.27±1.74)mg/L,对照组为(0.07±0.10)mg/L,3组间比较差异有统计学意义(P<0.01);
短句来源
     Results:The positive rate in the induced and spontaneous sputum from lung cancer patients and spontaneous sputum from benign lung disease patients were 80%,56.7%,and 13.3%,respectively,while the OD value of telomerase activity was 0.523±0.267,0.349±0.247,and 0.091±0.110,respectively.
     结果:肺癌患者的诱导痰、自然痰以及非肺癌患者诱导痰中的端粒酶阳性率和OD值分别为80.0%、56.7%、13.3%和0.523±0.267、0.349±0.247、0.091±0.110。
短句来源
     The viabilities of eosinophils and neutrophils were 67.1%±9.5% and 79.9%±10.5%,respectively.
     诱导痰中嗜酸性粒细胞和中性粒细胞活性分别为(67.1±9.5)%和(79.9±10.5)%。
短句来源
     After four weeks' administration, there were great decreases in percentage of total eosinophils (40 % ± 17 % vs 29 % ±11 %, P<0.01), activated (EG2+) eosinophils (28 % ±9 % vs 10 % ± 8 %, P < 0.01) and in the concentration of sputum ECP [ (373 ± 206) vs (220 ± 132) μg/L, P < 0.01].
     用茶碱治疗4周后,哮喘患者诱导痰中Eos百分数下降(40%±17% vs 29%±11%,P<0.01),EG~(2+)Eos百分数显著下降(28%±9% vs 10 %±8%,P<0.01),痰ECP明显下降[(373±206)vs(220±132)μg/L,P<0.01];
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  induced sputum
Nineteen specimens including 12 sputa, six bronchoalveolar lavage fluids (BALs) and one induced sputum were positive by DFA.
      
Three specimens were followed by induced sputum collection, 18 by BAL, six by lung biopsy, and two by pleural fluid aspiration.
      
In this paper we describe a high-throughput method for screening nasal lavage fluid samples and induced sputum samples for fucose.
      
Effect of Yufeining on induced sputum interleukin-8 in patients with chronic obstructive pulmonary disease at the stable phase
      
The effect of Ginkgo Biloba Extract on the expression of PKCα in the inflammatory cells and the level of IL-5 in induced sputum
      
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  sputum induction
Lung function measurements, bronchodilator tests, and sputum induction were performed.
      
A subgroup of 21 patients also underwent sputum induction and processing to assess airway inflammation before the SIC.
      
All had nondiagnostic sputum cytologic examinations or were unable to produce secretions despite vigorous attempts at sputum induction.
      
All subjects recovered the Sao2 fall within 5 min of the cessation of sputum induction.
      
All subjects were submitted to clinical examination, radiologic evaluation, sputum induction and laboratory testing.
      
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  (sputum induction)
Lung function measurements, bronchodilator tests, and sputum induction were performed.
      
A subgroup of 21 patients also underwent sputum induction and processing to assess airway inflammation before the SIC.
      
All had nondiagnostic sputum cytologic examinations or were unable to produce secretions despite vigorous attempts at sputum induction.
      
All subjects recovered the Sao2 fall within 5 min of the cessation of sputum induction.
      
All subjects were submitted to clinical examination, radiologic evaluation, sputum induction and laboratory testing.
      
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To develop a new method of sputum induction, asthmatics were instructed to inhale 4% sterile nebulised saline. The success rate, safety and validity of sputum induction were determined. The results indicated that sputum induction is safe, valid, and it may be useful in studying asthma or other pulmonary diseases.

为建立一种痰液诱导的方法。采用哮喘患者雾化吸入4%高渗盐水30min诱导痰波,结果:哮喘发作期患者的第一秒末用力呼气容积(FEV1)及第一秒末用力呼气容积在用力呼气容积中的比值(FEV1/FVC)较基础值有轻度下降,但所进行的62人次的诱导中,有61人次产生了足量的痰液,诱导痰中鳞形细胞所占百分比在哮端发作期、缓解期患者及正常对照者分别为4.55%、5.49%和5.30%。结论:本研究所建立的痰液诱导的方法具有可行性、安全性和可靠性,是无创性研究哮喘气道炎症的一种有效方法。

Objective To explore the role of sensory neuropeptide calcitonin gene related peptide (CGRP) in the pathogenesis of chronic airway inflammatory diseases COPD and bronchial asthma Methods Patients with COPD ( n =19), bronchial asthma ( n =14), all were in stable stage and 10 normal volunteers were examined After hypertonic saline inhalation challenge in all subjects, CGRP LI concentration in the induced sputum was measured by radioimmunoassay Cellular content was assayed by microscopic analysis,...

Objective To explore the role of sensory neuropeptide calcitonin gene related peptide (CGRP) in the pathogenesis of chronic airway inflammatory diseases COPD and bronchial asthma Methods Patients with COPD ( n =19), bronchial asthma ( n =14), all were in stable stage and 10 normal volunteers were examined After hypertonic saline inhalation challenge in all subjects, CGRP LI concentration in the induced sputum was measured by radioimmunoassay Cellular content was assayed by microscopic analysis, the relation between CGRP LI level and FEV 1 value was calculated by liner regression Results The sputum CGRP concentrations in patients with COPD and patients with asthma were (15 97±2 15)ng/L, (18 79±3 91)ng/L, respectively, both were significantly higher than those in normal volunteers (2 36±0 35)ng/L Moreover, CGRP concentrations in induced sputum in each disease group were correlated with the degree of airflow obstruction, r = -0 50 and -0 61, respectively ( P <0 05) The percentage of neutrophil cell count (64 9±2 9)% was significantly higher in patients with COPD ( P <0 01), while the percentage of eosinophil cell count (5 8±0 5)% was increased in patients with asthma ( P <0 01) Conclusions The data suggested that CGRP release may participate in the chronic inflammation of patients with COPD and bronchial asthma

目的 探讨慢性阻塞性肺疾病( C O P D) 和支气管哮喘患者气道分泌物中,感觉神经肽降钙素基因相关肽( C G R P) 释放在气道慢性炎症性疾病发病中的作用。方法 选择稳定期 C O P D 患者19 例、支气管哮喘患者14 例、正常对照组10 名,通过面罩吸入超声雾化的4 % 高张盐水诱导痰液,将获得的诱导痰涂片进行瑞氏姬姆萨染色计数细胞成分的变化,用放射免疫方法测定诱导痰中 C G R P免疫反应性物质( C G R P L I) 的含量改变,并进行 C G R P L I与一秒钟用力呼气容积( F E V1) 的相关性分析。结果 诱导痰中 C G R P L I含量在 C O P D 组为(1597 ±215)ng/ L,支气管哮喘组为(1879 ±391)ng/ L,与正常对照组(236 ±035)ng/ L 比较,差异有显著性( P< 005) ,而且与 F E V1 呈显著负相关( r= - 050 和- 061 , P 均< 005) 。 C O P D 患者诱导痰中中性粒细胞百分比为(649 ±...

目的 探讨慢性阻塞性肺疾病( C O P D) 和支气管哮喘患者气道分泌物中,感觉神经肽降钙素基因相关肽( C G R P) 释放在气道慢性炎症性疾病发病中的作用。方法 选择稳定期 C O P D 患者19 例、支气管哮喘患者14 例、正常对照组10 名,通过面罩吸入超声雾化的4 % 高张盐水诱导痰液,将获得的诱导痰涂片进行瑞氏姬姆萨染色计数细胞成分的变化,用放射免疫方法测定诱导痰中 C G R P免疫反应性物质( C G R P L I) 的含量改变,并进行 C G R P L I与一秒钟用力呼气容积( F E V1) 的相关性分析。结果 诱导痰中 C G R P L I含量在 C O P D 组为(1597 ±215)ng/ L,支气管哮喘组为(1879 ±391)ng/ L,与正常对照组(236 ±035)ng/ L 比较,差异有显著性( P< 005) ,而且与 F E V1 呈显著负相关( r= - 050 和- 061 , P 均< 005) 。 C O P D 患者诱导痰中中性粒细胞百分比为(649 ±29) % ,与支气管哮喘患者(265 ±15) % 和正常对照组(259 ±26) % 比较,差异有显著性( P< 001) ;支气管哮喘?

Objective To explore a simple and effective method of induced sputum and cellular analysis,and to investigate airway inflammation features in children with acute asthma.Methods A method to induce sputum with inhaled hypertonic saline was used in 37 acute asthmatic childhood patients and 48 normal subjects(control group) for collecting the sputum.A portion of the sputum treated with dithiothreitol(DTT) was performed to count the total cell in the hemocytomer and the other did differential cell counts in the...

Objective To explore a simple and effective method of induced sputum and cellular analysis,and to investigate airway inflammation features in children with acute asthma.Methods A method to induce sputum with inhaled hypertonic saline was used in 37 acute asthmatic childhood patients and 48 normal subjects(control group) for collecting the sputum.A portion of the sputum treated with dithiothreitol(DTT) was performed to count the total cell in the hemocytomer and the other did differential cell counts in the smear with Wright's stain and toluidine blue stain.Results In the asthmatic group,84% were successful in collecting the sputum and PEF value did not go down( P >0 05).The total cell counts were(11 2±8 9)×10 9/L in sputum from asthmatic subjects and (7 1±6 2)×10 9/L from the control subjects( P <0 05).The eosinophils and the mast cells of the asthmatic group were significantly higher than that of the control group( P <0 01) in the differential cell counts.Conclusion The analysis of the induced sputum and investigation of the airway inflammation was a safe and reliable method;eosinophils and mast cells were mainly effective cells in inflammatory response in asthma.

目的探讨简便有效的诱导痰液及细胞分析方法,了解儿童哮喘发作期气道炎症的特点。方法运用高渗盐水雾化吸入诱导痰液的方法,收集37例哮喘发作期患儿、48例正常儿童(对照组)痰液。一部分痰液经二硫苏糖醇(DTT)液化后,在血球计数板上行细胞总计数;另一部分痰液涂片经瑞氏、甲苯胺蓝染色行细胞分类计数。结果哮喘组84%取痰成功,诱导过程中呼气峰流速(PEF)未见下降(P>005)。痰液细胞总计数哮喘组为(112±89)×109/L,对照组为(71±62)×109/L(P<005)。嗜酸性粒细胞、肥大细胞在哮喘发作期气道中明显升高(P<001)。结论诱导痰液分析、评判哮喘患儿气道炎症是一种安全、可靠的新研究方法;嗜酸性细胞、肥大细胞为哮喘发作的主要效应细胞。

 
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