Conclusion Genotype B and C HBx were sussessfully expressed in Drosophila expression system. The HBx fusion proteins with high purity were obtained, and it will be helpful for the further study on the structural and functional differences between genotype B and C HBx.
Conclusions Transactivation competence of genotype B HBx was higher than that of genotype C HBx, while the antiproliferative and apoptosis effects of genotype B HBx was lower than of genotype C HBx. B and C genotype-specific functional differences of HBx may closely co-related with the pathogenicity of HBV.
connexin 43 expression in atrial myocardium is much more than that in ventricular myocardium. This distribution difference may be related with functional difference between atrium and ventricule.
The results demonstrated that there were 33 amino acids variations among four HCV core proteins, mainly of them located in five clustered regions: 4aa-21aa,68aa-78aa,106aa-121aa,139aa-163aa and 182aa-191aa as well. Amino acids variations within Core proteins may result in functional
The IFNγ activity and the levels of IL 1β and IL 6 in the serum, and the killing ability of the lymphocytes in the blood of the immunocompromised rats administrated IFNγ via aerosol had no difference with those of the control groups (P>0.05).
Since plant structures are correlated with plant functions, the changes in leaf anatomical characteristics in elevated temperature and CO2 may lead to functional differences.
First, oligodendrocyte precursor cells arise from different regions during development, and the cells from these distinct sites may have important functional differences.
These genetic variants may or may not result in functional differences in the receptors they encode.
Here, we present the first experimental evidence for specific functional differences that additionally exist between these two forms of human vocal communication.
The molecular details describing such protein interactions can shed light on how the proteins function and the functional differences between the two forms of CD8.
Domain of attraction of nonlinear functional difference systems
The domain of attraction of nonlinear functional difference systems is studied.
Positive periodic solutions of higher-dimensional nonlinear functional difference equations
In this paper, we apply a cone theoretic fixed point theorem to obtain sufficient conditions for the existence of multiple positive periodic solutions to the higher-dimensional functional difference equations of the form:
The functional difference between the proteins has been previously ascribed to the Lys-2 residue in S107.
Fortyfour male Kunming mice, weighing 20-25g. were used. The HpD was injected (10mg/kg) into the caudal vein of 32 mice individually. After 48 hours, the kidneys were radiated directly by the dye-laser for 10 minutes (630nm, 250-300J/cm~2). Then, the kidneys were observed at different times. 12 normal male mice served as control. The experiment demonstrated that when HpD was activated by laser, it could produce the necrotic effect on the renal tissues. The different structures of the kidney showed different...
Fortyfour male Kunming mice, weighing 20-25g. were used. The HpD was injected (10mg/kg) into the caudal vein of 32 mice individually. After 48 hours, the kidneys were radiated directly by the dye-laser for 10 minutes (630nm, 250-300J/cm~2). Then, the kidneys were observed at different times. 12 normal male mice served as control. The experiment demonstrated that when HpD was activated by laser, it could produce the necrotic effect on the renal tissues. The different structures of the kidney showed different susceptibility to HpD-laser. The proximal convoluted tubules and capillaries were injured earlier than the distal convoluted tubules and the collecting tubules. The first morphologic changes observed electron microscopically were the swelling of mitochondria and the formation of vesicles on the cell membrane. Finally, they were completely disrupted. The damages of lysosomes, endoplasmic reticula, ribosomes and cell nucleus followed. The activity of some enzymes in the kidney were inhibited. The sequence of the extents of the enzymes being inhibited was AkP, AcP, Cytox, SDH. The mucopolysaccharides ran off the brush border in proximal convoluted tubules. The results of this study suggested that the various susceptibilities to HpD-laser are chiefly due to the different structures and their functional conditions in the kidney. The main photodynamic effect is presented as the injury of the membrane system of the cell.
A large number of viable and pure new-born Pig pancreatic islets were Seperated by 0.25% collagenate digestion and cultured in vitro.The islets were than microencapsulated by a new developed Ba linked alginate membrane technoque. The detection of both the insulin level and the insulin-releasing experiment of the culture suspension,and the pathologic study showed no difference between the microencapsulated and non-microencapsulated group.This result that that this microencapsulation mem brane and the technique...
A large number of viable and pure new-born Pig pancreatic islets were Seperated by 0.25% collagenate digestion and cultured in vitro.The islets were than microencapsulated by a new developed Ba linked alginate membrane technoque. The detection of both the insulin level and the insulin-releasing experiment of the culture suspension,and the pathologic study showed no difference between the microencapsulated and non-microencapsulated group.This result that that this microencapsulation mem brane and the technique of one-step mocroencapsulating could keep excellent islets viability and function without damage.
A comparative study was made on the distribution of α-and β-adrenoceptors between rat basilar(BA) and renal arteries(RA).The results showed that(1) the endothelium-independent relaxation due to β-agonism was more significant in BA than that in RA;(2)there was no α1-adrenoceptor-mediated vasoconstriction in most of the BA,only a small part of BA showed constriction in response to α1-agonism,but with low affinity and efficacy and a desensitization tendency;(3)no response to α2-agonist BHT 920(10-5 mol/L)in BA...
A comparative study was made on the distribution of α-and β-adrenoceptors between rat basilar(BA) and renal arteries(RA).The results showed that(1) the endothelium-independent relaxation due to β-agonism was more significant in BA than that in RA;(2)there was no α1-adrenoceptor-mediated vasoconstriction in most of the BA,only a small part of BA showed constriction in response to α1-agonism,but with low affinity and efficacy and a desensitization tendency;(3)no response to α2-agonist BHT 920(10-5 mol/L)in BA was shown,either in the presence or absence of endothelium,But in RA there was relaxation in the presence of endothelium and constriction in its absence,The above results suggest that there is a scarce distribution of α1-and α2-adrenoceptors,but an abundant distribution of β-adrenoceptor in basilar artery compared with that in renal artery. The α1subtype in BA is different from the α1-subtype in RA,and the α2-receptor which mediates direct smooth muscle constriction and endothelium-dependent relaxation is highly heterogeneous between basilar and renal arterles.
功能差异
functional differences
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