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肝移植受者
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  liver transplantation recipients
     Comparing steady-state pharmacokinetics of ciclosporin in kidney and liver transplantation recipients,the elimination rate constant (β) in liver transplantation recipients was significantly decreased,T_(1/2β),T_(1/2α),t_(max) and the time of reaching average steady concentration (t_(css)) in liver transplantation recipients were significantly extended.
     肝移植受者较肾移植β显著减小,T1/2β、T1/2α延长,t_(max)和达平均稳态血药浓度的时间(tcss)后移。
短句来源
     Cost-effectiveness Analysis of3Immunosuppressants in the Treatment of Liver Transplantation Recipients
     3种免疫抑制药应用于肝移植受者的成本-效果分析
短句来源
     Investigation of quality of life of liver transplantation recipients
     肝移植受者生存质量研究
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     CONCLUSION:It is more economical to use domestic CsA in liver transplantation recipients.
     结论:国产环孢素A应用于肝移植受者更经济。
短句来源
     Distribution and elimination of ciclosporin in liver transplantation recipients are significantly slower than those in kidney transplantation recipients and it is easy to produce ciclosporin cumulation.
     肝移植受者的CsA分布和消除较肾移植显著减慢,易发生蓄积。
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  liver transplant recipients
     Nine cases of Liver transplant recipients were detected positive for SRY and DYZ-1 region of the Y chromosome by PCR technique.
     利用PCR法检测 ,9例肝移植受者Y染色体特异的基因片断SRY和DYZ 1均为阳性。
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     OBJECTIVE To study clinical pharmacokinetics of cyclosporine A in liver transplant recipients and optimize cyclosporine A therapeutic drug monitoring strategy.
     目的:研究肝移植受者环孢素A临床药动学特点,优化环孢素A治疗药物监测方案。
短句来源
     Methods PCR restriction fragment polymorphisms assay was used to detect the distribution of genotypes, interleukin 10 (IL-10)-592, -1082 in 122 adult liver transplant recipients and its relation with the occurrence of acute rejection.
     方法 应用PCR限制性片段长度多态性分析法 ,检测 12 2例肝移植受者IL 10基因启动子的 2个多态位点 - 10 82和 - 5 92的各种基因型的分布 ,并分析它们与急性排斥反应的关系。
短句来源
     Methods 150 plasma samples and leukocytes samples collected from 59 bone marrow transplant recipients and 9 liver transplant recipients were tested by qualitative CMV PCR assay in parallel;
     方法应用定性PCR检测59例骨髓移植受者和9例肝移植受者的150份外周血标本中的巨细胞病毒DNA,比较外周血白细胞和血浆的检出差异;
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     Preliminary establishment of the therapeutic window concentration of tacrolimus in liver transplant recipients
     肝移植受者他克莫司治疗窗浓度的初步确定
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  recipients with liver transplantation
     Application of ~(18) F-FDG imaging in screening of the recipients with liver transplantation
     ~(18)氟脱氧葡萄糖显像正电子发射体层摄影术在肝移植受者筛选中的应用
短句来源
     Objective To discuss the clinical values of 18 F-FDG imaging in screening of the recipients with liver transplantation.
     目的 探讨18氟脱氧葡萄糖(18F FDG)符合线路显像在肝移植受者筛选中的临床应用价值。
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  “肝移植受者”译为未确定词的双语例句
     Detection of CD95 and CD95L mRNA expression after liver transplantation using SYBR realtime PCR during acute rejection
     SYBR荧光实时定量PCR检测肝移植受者CD95和CD95L mRNA表达
短句来源
     Impact of induction with different immunosuppressants on CD4~+ CD25~+ regulatory T cells in liver transplanted recipients
     不同免疫抑制诱导治疗对肝移植受者CD4~+ CD25~(+high)细胞的影响
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     All patients' PON1 activity was lower than the control group significantly (P < 0. 001) , PON1 activity begins to elevate continuously 5 min after opening and shows obviously higher than that of pre-operation 90 min[(47. 1±2.4) U/ml] after opening(P < 0. 05 ).
     17例肝移植受者术前血清PON1活性比对照组低(P<0.001)。 在门静脉开放后5min始升高,开放后90 min[(47.1±2.4)U/ml]较术前明显增高(P<0.05),术后第1、2 d继续升高。
短句来源
     (Results)Among 41 LT recipients,14 patients died postoperatively and the mortality rate was 34.15%.
     结果41例肝移植受者中,死亡14例(34.15%)。
短句来源
     Methods Fluorescein-labeled monoclonal antibodies and flow cytometry was to determine the T-cell subgroups and the expression of CD28, CD152 and ICOS on peripheral T cells of allo-liver recipients 1, 2, 3 and 4 weeks after treatment with FK506. And health volunteers and patients who suffered severe hepatic diseases and intended to receive hepatic transplantation were used as controls.
     方法采用荧光标记单克隆抗体和流式细胞技术,测定术后采用FK506治疗的肝移植受者(FK506治疗组)在用FK506后1、2、3、4周时的外周血T淋巴细胞亚群及其表面共刺激分子CD28、CD152和ICOS分子的表达情况,以健康志愿者(健康对照组)和患终末期肝脏疾病拟行肝移植者(肝病对照组)为对照。
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  liver transplantation recipients
We compared results using Neoral versus Sandimmune, each in combination with steroid and azathioprine immunosuppression, in primary liver transplantation recipients.
      
The BARIGA LDLT (biliary anastomosis in right graft for adult living donor liver transplantation recipients) with end-to-side or end-to-end hepatico-hepaticostomy was used in five recipients of right grafts (segments 5-8).
      
Several studies of selective bowel decontamination in liver transplantation recipients have been performed.
      
Seropositivity in liver transplantation recipients as a predictor of cytomegalovirus disease.
      
These compounds form the backbone of immunosuppression in liver transplantation recipients.
      
  liver transplant recipients
In ten auxiliary partial liver transplant recipients selective bowel decontamination (SBD) was used to reduce infections due to gram-negative microorganisms and fungi.
      
There are three indications for SDD, as follows: (i) trauma patients; (ii) liver transplant recipients and (iii) outbreaks of multi-resistant organisms.
      
As multiple-resistant enterococci may colonize and reinfect liver transplant recipients for such a long time, preoperative antibiotic therapy should be administered cautiously in order not to select these organisms.
      
Risk factors for fatal recurrence of liver transplant recipients with hepatocellular carcinoma in the first year
      
This review focuses on the epidemiology, natural history, and prophylactic strategies to reduce the risk of de novo hepatitis B in liver transplant recipients who receive anti-HBc-positive grafts.
      
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Objective To investigate the impact of venacavaplasty on the piggyback liver transplantation and on the prevention of hepatic outflow block.Methods Three patients with the end-stage hepatic diseases were selected as recipients,who received a modified piggyback liver transplantation with venacavaplasty under single veno-venous bypass.Results All the recipients had stability of hemodynamic circulation,with anhepatic phase and hemorrhage decreased during the period of cava occlusion.All the patients recovered...

Objective To investigate the impact of venacavaplasty on the piggyback liver transplantation and on the prevention of hepatic outflow block.Methods Three patients with the end-stage hepatic diseases were selected as recipients,who received a modified piggyback liver transplantation with venacavaplasty under single veno-venous bypass.Results All the recipients had stability of hemodynamic circulation,with anhepatic phase and hemorrhage decreased during the period of cava occlusion.All the patients recovered quickly with good liver function, without any complications postoperatively.Conclusion Venacavaplasty may overcome hepatic outflow block in piggyback liver transplantation and this technique can reduce both anhepatic phase and venacava block complications,and minimize the hemodynamic interference with the recipients.

目的 探讨腔静脉成形术在背驮式原位肝移植中的应用价值及在防止移植肝流出道阻塞并发症中的作用。方法  3例终末期肝病病人选为肝移植受者。供肝的下腔静脉及受体的肝后下腔静脉 (包括肝静脉 )均作了成形术 ,在单独股 -腋静脉转流术下行改良背驮式肝移植术。结果  3例病人术中均较平稳 ,手术时间和无肝期缩短 ,出血量减少 ,术后肝功能恢复快 ,恢复顺利 ,无并发症发生。结论 腔静脉成形术可防止背驮式肝移植肝静脉流出道阻塞 ,术中对受体的血流动力学干扰小 ,并可缩短无肝期和减少腔静脉梗阻并发症的发生。

Objective To evaluate the significance of interleukin 6 (IL 6) in bile for the diagnosis of acute rejection rejection after liver transplantation.Methods Eighteen patients who underwent orthotopic liver transplantation were included in this study.After liver transplantation,bile and blood were collected daily,and IL 6 levels were measured.Results Serum IL 6 levels increased only in 2 recipients when acute rejection developed.There were no significant difference in serum mean IL 6 levels between acute...

Objective To evaluate the significance of interleukin 6 (IL 6) in bile for the diagnosis of acute rejection rejection after liver transplantation.Methods Eighteen patients who underwent orthotopic liver transplantation were included in this study.After liver transplantation,bile and blood were collected daily,and IL 6 levels were measured.Results Serum IL 6 levels increased only in 2 recipients when acute rejection developed.There were no significant difference in serum mean IL 6 levels between acute rejection and no rejection groups ( P > 0.05) of transplant recipients.In contrast,bile IL 6 levels increased significantly in patients with acute rejection compared with patients with no rejection.Patients who had no rejection had low levels of bile IL 6.In patients with acute rejection,bile IL 6 significantly increased ( P <0.01),but decreased in response to anti rejection therapy.Conclusions Measurement of IL 6 in bile may be a useful,noninvasive indicator for diagnosing acute rejection.

目的 评价胆汁 IL - 6水平在诊断肝移植急性排斥反应中的意义。方法 连续 3周监测 18例肝移植受者术后血清及胆汁 IL - 6水平 ,观察其与急性排斥反应的关系。结果 在急性排斥反应 (AR)组 ,88.9%的患者在排斥发作时胆汁 IL - 6水平明显升高 ,与非排斥组比较有显著性差异 (P<0 .0 1)。当 AR经激素冲击治疗逆转后 ,胆汁 IL - 6下降至排斥前的水平。在 AR组 ,仅有 2例受者在排斥发作时血清 IL - 6水平升高 ,与非排斥组相比 ,血清IL - 6水平无显著性差异 (P>0 .0 5 )。结论 胆汁 IL - 6水平可以作为诊断急性排斥反应敏感、较特异及非侵袭性的诊断手段 ,同时 ,其水平可作为观察抗排异治疗是否有效的指标。

Objective To study the relationship between IL-10 gene polymorphisms and acute rejection following liver transplantation.Methods PCR restriction fragment polymorphisms assay was used to detect the distribution of genotypes, interleukin 10 (IL-10)-592, -1082 in 122 adult liver transplant recipients and its relation with the occurrence of acute rejection. All patients received standard immunosuppression with corticosteroids, azathioprine and cyclosporine or FK506.Results 31 (26%) patients developed acute rejection...

Objective To study the relationship between IL-10 gene polymorphisms and acute rejection following liver transplantation.Methods PCR restriction fragment polymorphisms assay was used to detect the distribution of genotypes, interleukin 10 (IL-10)-592, -1082 in 122 adult liver transplant recipients and its relation with the occurrence of acute rejection. All patients received standard immunosuppression with corticosteroids, azathioprine and cyclosporine or FK506.Results 31 (26%) patients developed acute rejection 1-18 weeks following transplantation. The acute rejection rate in liver transplant patients with A/A, C/A, C/C genotypes at IL-10 gene promoter -592 position was 1 6.7%,19% and 29%,respectively (P> 0.05); the acute rejection rate in liver transplant patients with G/G, G/A, A/A genotypes at IL-10 gene promoter -1082 position was 33%, 25% and 17.9%, respectively (P> 0.05).Conclusion There were no association between IL-10 gene polymorphisms and acute rejection following liver transplantation.

目的 探讨肝移植受者白细胞介素 10 (IL 10 )基因多态性与急性排斥反应的关系。方法 应用PCR限制性片段长度多态性分析法 ,检测 12 2例肝移植受者IL 10基因启动子的 2个多态位点 - 10 82和 - 5 92的各种基因型的分布 ,并分析它们与急性排斥反应的关系。结果 IL 10 - 5 92位点 ,A/A ,C/A ,C/C等基因型间的急性排斥反应发生率分别为 16.7%,19%,2 9%,相互比较 ,差异不显著 (P >0 .0 5 ) ;IL 10 - 10 82位点 ,尽管G/G基因型的急性排斥反应发生率 ( 3 3 %)高于A/A型( 18%) ,但差异仍不显著 (P >0 .0 5 )。结论 IL 10基因多态性与肝移植受者术后急性排斥反应无确切关系。

 
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