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Temperature distribution in the human brain during ultrasound hyperthermia
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One of the important applications of ultrasound hyperthermia is the temperature elevation at specified locations in the human brain.
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Treatment of malignant brain tumors with focused ultrasound hyperthermia and radiation: results of a phase I trial
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Figure 1 shows an acoustic field of a concave ultrasound hyperthermia device measured by sonoluminescence.
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| | The transient temperature distributions inside the human body during ultrasonic hyperthermia have been calculated by a simplified finite element method for resolving the bio-heat equation with certain boundary conditions. The influence of the focusing,blood perfusion and skin surface temperature on the temperature field has also been investigated. A program for noninvasive monitoring in ultrasonic hyperthemia has been proposed. | | 本文用简化的有限元法解算了在一定边界条件下的生物热传导方程,得到了超声热疗中人体里的瞬态温度分布,并讨论了超声聚焦、血流扩散和皮表温度等对超声加热的温度场的影响,提供了一种超声热疗中无损控温的方案. | | 文摘来源 | | Porpose To evaluate temperature distributions in heating area and the effect for advancedmalignancies treated with combination radiotherapy with ultrasound( US) hvperthermia , and to find effective methods for minimizingiziang the side effect. Materials and Methods By using SONOTHERM - 1000 US hyperthermia system, we measured experimentally temperature distributiosns with multiple temperature setnsors in a phantom and porcitne model . Aluminum paper shields were used to prevent overheating of bone . 17 pati... | | 了解超声热疗的温度分布特征,寻求减轻临床常见副作用的有效对策,同时对晚期肿瘤的治疗结果进行初步评价。材料与方法应用SONOTHERM-1000超声热疗治癌系统,分别在体模和家猪实测不同深度的温度分布,分别采用铝箔纸屏蔽骨头和适当减少水囊内水量的方法减轻骨头和皮肤过热。并采用常规放疗加超声热疗治疗17例晚期恶性肿瘤。结果用不同频率的超声加温可获得不同深度的温度分布,温度在骨表面比在软组织高6~8℃。铝箔纸对超声辐射有明显的屏蔽效果。在临床可评价病例的有效率(CR+PR)为69.3%。结论本热疗系统可对面积为15cm×15cm、深度在8cm以内的实体肿瘤实行有效加温,且放疗配合超声热疗可进一步提高巨块肿瘤的局部控制率。 | | 文摘来源 | | A formula for calculating sound field generated by a concave spherical focused radiator through coupling liquid entering into soft tissues is derived. Effects of different couplants, different widths of coupling layers and temperature on acoustic focusing are studied carefully, and some significant results for ultrasound hyperthermia treatments are reported. | | 本文推导了凹球面聚焦换能器产生的声波经耦合液进入软组织后的声场计算公式,并对不同耦合液、耦合层厚度、温度对声聚焦的影响进行了研究,得到了一些对超声热疗具有指导意义的结果。 | | 文摘来源 | |   | | << 更多相关文摘 |
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